Endopeptidáza závislá na vápníku, která je specifická pro štěpení na argininu v blízkosti párových bazických zbytků. Štěpí řadu prohormonů, včetně pro-opiomelanokortinu, proreninu, proenkefalinu, prodynorfinu, prosomatostatinu a proinzulinu.

A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN.

DUI

D045664 MeSH Prohlížeč

CUI

M0103931

Předchozí užití

Aspartic Endopeptidases (1991-2003)

Historická pozn.

2004; for PC1 PROHORMONE CONVERTASE, NEUROENDOCRINE CONVERTASE PC1, PC3 ENDOPROTEASE, PROHORMONE CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 1991-2003; for PC1 ENDOPROTEASE & PC3 PROHORMONE CONVERTASE use PROPROTEIN CONVERTASE (NM) 1993-2003; for PROPROTEIN CONVERTASE SPC3 use PROPROTEIN CONVERTASE (NM) 2001-2003; for PROINSULIN CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 2002-2003

Veřejná pozn.

2004; PC1 PROHORMONE CONVERTASE, NEUROENDOCRINE CONVERTASE PC1, PC3 ENDOPROTEASE & PROHORMONE CONVERTASE 1 were indexed under ASPARTIC ENDOPEPTIDASES 1991-2003; PC1 ENDOPROTEASE & PC3 PROHORMONE CONVERTASE were indexed under ASPARTIC ENDOPEPTIDASES 1993-2003; PROPROTEIN CONVERTASE SPC3 was indexed under ASPARTIC ENDOPEPTIDASES 2001-2003; PROINSULIN CONVERTASE 1 was indexed under ASPARTIC ENDOPEPTIDASES 2002-2003;