Mannose-Binding Protein-Associated Serine Proteases [serinové proteasy asociované s proteinem vázajícím mannosu]
- Terms
-
proteázy MASP
protein související s MASP
serinová proteáza asociovaná s MBL
serinové proteázy asociované s manózou
serinové proteázy asociované s MBL
-
Mannan-Binding Lectin Serine Proteases
Mannose-Binding Protein-Associated Serine Protease
MASP
MASP Proteases
MASP-Related Protein
MASPs
MBL-Associated Serine Proteases
MBP-Associated Serine Protease
MBP-Associated Serine Protease-Related Protein
Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
- Annotation
- see SCR for organism-specific terms
- DUI
- D050606 MeSH Browser
- CUI
- M0233323
- Previous indexing
- Mannose-Binding Lectins (1992-2005); Serine Endopeptidases (1992-2005)
- History note
- 2006 (1994)
- Public note
- 2006; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES was indexed under SERINE ENDOPEPTIDASES 1994-2005
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0