serinové proteasy asociované s proteinem vázajícím mannosu [Mannose-Binding Protein-Associated Serine Proteases]

tematický
2
Termíny

proteázy MASP
protein související s MASP
serinová proteáza asociovaná s MBL
serinové proteázy asociované s manózou
serinové proteázy asociované s MBL

 

Mannan-Binding Lectin Serine Proteases
Mannose-Binding Protein-Associated Serine Protease
MASP
MASP Proteases
MASP-Related Protein
MASPs
MBL-Associated Serine Proteases
MBP-Associated Serine Protease
MBP-Associated Serine Protease-Related Protein

Perzistentní odkaz   https://www.medvik.cz/link/D050606
Definice

Sérové serinové proteázy, které se podílejí na aktivaci komplementu. Aktivují se po vytvoření komplexu s lektinem vázajícím manózu, proto jsou také známé jako serinové proteázy asociované s manózou (MASP). Štěpí komplement C4 a komplement C2 za vzniku C4b2a, tedy C3-konvertázy klasické dráhy komplementu.

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

Anotace
see SCR for organism-specific terms
DUI
D050606 MeSH Prohlížeč
CUI
M0233323
Předchozí užití
Mannose-Binding Lectins (1992-2005); Serine Endopeptidases (1992-2005)
Historická pozn.
2006 (1994)
Veřejná pozn.
2006; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES was indexed under SERINE ENDOPEPTIDASES 1994-2005

Povolená podhesla

AN
analýza
AI
antagonisté a inhibitory
AD
aplikace a dávkování
BI
biosyntéza
CS
chemická syntéza
CH
chemie
HI
dějiny
EC
ekonomika
PK
farmakokinetika
PD
farmakologie
PH
fyziologie
GE
genetika
IM
imunologie
IP
izolace a purifikace
CL
klasifikace
ME
metabolismus 1
UR
moč
CF
mozkomíšní mok
DF
nedostatek
ST
normy
PO
otrava
AE
škodlivé účinky
TU
terapeutické užití
TO
toxicita
DE
účinky léků
RE
účinky záření
UL
ultrastruktura
SD
zásobování a distribuce

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.811 enzymy 1 551
D08.811.277 hydrolasy 475
D08.811.277.656 proteasy 560
D08.811.277.656.300 endopeptidasy 211
D08.811.277.656.300.760 serinové endopeptidasy 138
D08.811.277.656.300.760.030 akrosin 14
D08.811.277.656.300.760.066 kathepsin G 4
D08.811.277.656.300.760.103 chymasy 5
D08.811.277.656.300.760.176 chymotrypsin 133
D08.811.277.656.300.760.198 komplement - faktor B 3
D08.811.277.656.300.760.200 komplement - faktor D 6
D08.811.277.656.300.760.210 komplement - faktor I
D08.811.277.656.300.760.247 endopeptidasa K 7
D08.811.277.656.300.760.284 enteropeptidasa 3
D08.811.277.656.300.760.300 faktor VIIa 110
D08.811.277.656.300.760.310 faktor IXa 6
D08.811.277.656.300.760.315 faktor Xa 189
D08.811.277.656.300.760.320 faktor XIa 7
D08.811.277.656.300.760.324 faktor XIIa 2
D08.811.277.656.300.760.330 plasmin 44
D08.811.277.656.300.760.353 furin 2
D08.811.277.656.300.760.397 granzymy 11
D08.811.277.656.300.760.420 serinová proteasa HTRA1 1
D08.811.277.656.300.760.431 serinová proteasa HTRA2
D08.811.277.656.300.760.442 kalikreiny 39
D08.811.277.656.300.760.471 laktoferrin 32
D08.811.277.656.300.760.501 serinové proteasy asociované s proteinem vázajícím mannosu 2
D08.811.277.656.300.760.530 myeloblastin 8
D08.811.277.656.300.760.560 pankreatická elastasa 93
D08.811.277.656.300.760.635 aktivátory plazminogenu 56
D08.811.277.656.300.760.637 prolyloligopeptidasy 3
D08.811.277.656.300.760.638 pronasa 4
D08.811.277.656.300.760.640 proproteinkonvertasa 1 4
D08.811.277.656.300.760.646 proproteinkonvertasa 2
D08.811.277.656.300.760.648 proproteinkonvertasa 5
D08.811.277.656.300.760.718 proproteinkonvertasa subtilisin/kexin typu 9 269
D08.811.277.656.300.760.753 protein reelin
D08.811.277.656.300.760.787 subtilisiny 7
D08.811.277.656.300.760.855 trombin 228
D08.811.277.656.300.760.875 tkáňový aktivátor plazminogenu 238
D08.811.277.656.300.760.895 trypsin 257
D08.811.277.656.300.760.902 tryptasy 37
D08.811.277.656.300.760.910 aktivátor plazminogenu urokinázového typu 61
D08.811.277.656.300.760.955 venombin A 1
D08.811.277.656.959 serinové proteasy 21
D08.811.277.656.959.350 serinové endopeptidasy 138
D08.811.277.656.959.350.030 akrosin 14
D08.811.277.656.959.350.066 kathepsin G 4
D08.811.277.656.959.350.103 chymasy 5
D08.811.277.656.959.350.176 chymotrypsin 133
D08.811.277.656.959.350.198 komplement - faktor B 3
D08.811.277.656.959.350.200 komplement - faktor D 6
D08.811.277.656.959.350.210 komplement - faktor I
D08.811.277.656.959.350.247 endopeptidasa K 7
D08.811.277.656.959.350.284 enteropeptidasa 3
D08.811.277.656.959.350.300 faktor VIIa 110
D08.811.277.656.959.350.310 faktor IXa 6
D08.811.277.656.959.350.315 faktor Xa 189
D08.811.277.656.959.350.320 faktor XIa 7
D08.811.277.656.959.350.324 faktor XIIa 2
D08.811.277.656.959.350.330 plasmin 44
D08.811.277.656.959.350.353 furin 2
D08.811.277.656.959.350.397 granzymy 11
D08.811.277.656.959.350.420 serinová proteasa HTRA1 1
D08.811.277.656.959.350.431 serinová proteasa HTRA2
D08.811.277.656.959.350.442 kalikreiny 39
D08.811.277.656.959.350.471 laktoferrin 32
D08.811.277.656.959.350.501 serinové proteasy asociované s proteinem vázajícím mannosu 2
D08.811.277.656.959.350.530 myeloblastin 8
D08.811.277.656.959.350.560 pankreatická elastasa 93
D08.811.277.656.959.350.635 aktivátory plazminogenu 56
D08.811.277.656.959.350.638 pronasa 4
D08.811.277.656.959.350.640 proproteinkonvertasa 1 4
D08.811.277.656.959.350.646 proproteinkonvertasa 2
D08.811.277.656.959.350.648 proproteinkonvertasa 5
D08.811.277.656.959.350.718 proproteinkonvertasa subtilisin/kexin typu 9 269
D08.811.277.656.959.350.753 protein reelin
D08.811.277.656.959.350.787 subtilisiny 7
D08.811.277.656.959.350.855 trombin 228
D08.811.277.656.959.350.875 tkáňový aktivátor plazminogenu 238
D08.811.277.656.959.350.895 trypsin 257
D08.811.277.656.959.350.902 tryptasy 37
D08.811.277.656.959.350.910 aktivátor plazminogenu urokinázového typu 61
D08.811.277.656.959.350.955 venombin A 1
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 581
D12.776.124 krevní proteiny 909
D12.776.124.486 imunoproteiny 14
D12.776.124.486.274 komplement 353
D12.776.124.486.274.045 enzymy aktivující komplement 3
D12.776.124.486.274.045.387 C3-C5-konvertasy komplementu
D12.776.124.486.274.045.387.500 C3-C5-konvertasy alternativní dráhy komplementu
D12.776.124.486.274.045.387.750 C3-C5-konvertasy klasické dráhy komplementu
D12.776.124.486.274.045.387.875 serinové proteasy asociované s proteinem vázajícím mannosu 2

MASP-1 protein, mouse Chemical MeSH Prohlížeč

MASP-2 protein, mouse Chemical MeSH Prohlížeč

MASP-3 protein, mouse Chemical MeSH Prohlížeč

MASP1 protein, human Chemical MeSH Prohlížeč

MASP2 protein, human Chemical MeSH Prohlížeč

Masp1 protein, rat Chemical MeSH Prohlížeč

Masp2 protein, rat Chemical MeSH Prohlížeč

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