Mannose-Binding Protein-Associated Serine Proteases [serinové proteasy asociované s proteinem vázajícím mannosu]

topical
2
Terms

proteázy MASP
protein související s MASP
serinová proteáza asociovaná s MBL
serinové proteázy asociované s manózou
serinové proteázy asociované s MBL

 

Mannan-Binding Lectin Serine Proteases
Mannose-Binding Protein-Associated Serine Protease
MASP
MASP Proteases
MASP-Related Protein
MASPs
MBL-Associated Serine Proteases
MBP-Associated Serine Protease
MBP-Associated Serine Protease-Related Protein

Persistent link   https://www.medvik.cz/link/D050606
Definition

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

Annotation
see SCR for organism-specific terms
DUI
D050606 MeSH Browser
CUI
M0233323
Previous indexing
Mannose-Binding Lectins (1992-2005); Serine Endopeptidases (1992-2005)
History note
2006 (1994)
Public note
2006; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES was indexed under SERINE ENDOPEPTIDASES 1994-2005

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.277 Hydrolases 475
D08.811.277.656 Peptide Hydrolases 559
D08.811.277.656.300 Endopeptidases 211
D08.811.277.656.300.760 Serine Endopeptidases 138
D08.811.277.656.300.760.030 Acrosin 14
D08.811.277.656.300.760.066 Cathepsin G 4
D08.811.277.656.300.760.103 Chymases 5
D08.811.277.656.300.760.176 Chymotrypsin 133
D08.811.277.656.300.760.198 Complement Factor B 3
D08.811.277.656.300.760.200 Complement Factor D 5
D08.811.277.656.300.760.210 Complement Factor I
D08.811.277.656.300.760.247 Endopeptidase K 7
D08.811.277.656.300.760.284 Enteropeptidase 3
D08.811.277.656.300.760.300 Factor VIIa 110
D08.811.277.656.300.760.310 Factor IXa 6
D08.811.277.656.300.760.315 Factor Xa 189
D08.811.277.656.300.760.320 Factor XIa 7
D08.811.277.656.300.760.324 Factor XIIa 2
D08.811.277.656.300.760.330 Fibrinolysin 44
D08.811.277.656.300.760.353 Furin 2
D08.811.277.656.300.760.397 Granzymes 11
D08.811.277.656.300.760.420 High-Temperature Requirement A Serine Peptidase 1 1
D08.811.277.656.300.760.431 High-Temperature Requirement A Serine Peptidase 2
D08.811.277.656.300.760.442 Kallikreins 39
D08.811.277.656.300.760.471 Lactoferrin 32
D08.811.277.656.300.760.501 Mannose-Binding Protein-Associated Serine Proteases 2
D08.811.277.656.300.760.530 Myeloblastin 8
D08.811.277.656.300.760.560 Pancreatic Elastase 93
D08.811.277.656.300.760.635 Plasminogen Activators 56
D08.811.277.656.300.760.637 Prolyl Oligopeptidases 3
D08.811.277.656.300.760.638 Pronase 4
D08.811.277.656.300.760.640 Proprotein Convertase 1 4
D08.811.277.656.300.760.646 Proprotein Convertase 2
D08.811.277.656.300.760.648 Proprotein Convertase 5
D08.811.277.656.300.760.718 Proprotein Convertase 9 269
D08.811.277.656.300.760.753 Reelin Protein
D08.811.277.656.300.760.787 Subtilisins 7
D08.811.277.656.300.760.855 Thrombin 228
D08.811.277.656.300.760.875 Tissue Plasminogen Activator 237
D08.811.277.656.300.760.895 Trypsin 257
D08.811.277.656.300.760.902 Tryptases 35
D08.811.277.656.300.760.910 Urokinase-Type Plasminogen Activator 61
D08.811.277.656.300.760.955 Venombin A 1
D08.811.277.656.959 Serine Proteases 21
D08.811.277.656.959.350 Serine Endopeptidases 138
D08.811.277.656.959.350.030 Acrosin 14
D08.811.277.656.959.350.066 Cathepsin G 4
D08.811.277.656.959.350.103 Chymases 5
D08.811.277.656.959.350.176 Chymotrypsin 133
D08.811.277.656.959.350.198 Complement Factor B 3
D08.811.277.656.959.350.200 Complement Factor D 5
D08.811.277.656.959.350.210 Complement Factor I
D08.811.277.656.959.350.247 Endopeptidase K 7
D08.811.277.656.959.350.284 Enteropeptidase 3
D08.811.277.656.959.350.300 Factor VIIa 110
D08.811.277.656.959.350.310 Factor IXa 6
D08.811.277.656.959.350.315 Factor Xa 189
D08.811.277.656.959.350.320 Factor XIa 7
D08.811.277.656.959.350.324 Factor XIIa 2
D08.811.277.656.959.350.330 Fibrinolysin 44
D08.811.277.656.959.350.353 Furin 2
D08.811.277.656.959.350.397 Granzymes 11
D08.811.277.656.959.350.420 High-Temperature Requirement A Serine Peptidase 1 1
D08.811.277.656.959.350.431 High-Temperature Requirement A Serine Peptidase 2
D08.811.277.656.959.350.442 Kallikreins 39
D08.811.277.656.959.350.471 Lactoferrin 32
D08.811.277.656.959.350.501 Mannose-Binding Protein-Associated Serine Proteases 2
D08.811.277.656.959.350.530 Myeloblastin 8
D08.811.277.656.959.350.560 Pancreatic Elastase 93
D08.811.277.656.959.350.635 Plasminogen Activators 56
D08.811.277.656.959.350.638 Pronase 4
D08.811.277.656.959.350.640 Proprotein Convertase 1 4
D08.811.277.656.959.350.646 Proprotein Convertase 2
D08.811.277.656.959.350.648 Proprotein Convertase 5
D08.811.277.656.959.350.718 Proprotein Convertase 9 269
D08.811.277.656.959.350.753 Reelin Protein
D08.811.277.656.959.350.787 Subtilisins 7
D08.811.277.656.959.350.855 Thrombin 228
D08.811.277.656.959.350.875 Tissue Plasminogen Activator 237
D08.811.277.656.959.350.895 Trypsin 257
D08.811.277.656.959.350.902 Tryptases 35
D08.811.277.656.959.350.910 Urokinase-Type Plasminogen Activator 61
D08.811.277.656.959.350.955 Venombin A 1
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.124 Blood Proteins 909
D12.776.124.486 Immunoproteins 14
D12.776.124.486.274 Complement System Proteins 352
D12.776.124.486.274.045 Complement Activating Enzymes 3
D12.776.124.486.274.045.387 Complement C3-C5 Convertases
D12.776.124.486.274.045.387.500 Complement C3-C5 Convertases, Alternative Pathway
D12.776.124.486.274.045.387.750 Complement C3-C5 Convertases, Classical Pathway
D12.776.124.486.274.045.387.875 Mannose-Binding Protein-Associated Serine Proteases 2

MASP-1 protein, mouse Chemical MeSH Browser

MASP-2 protein, mouse Chemical MeSH Browser

MASP-3 protein, mouse Chemical MeSH Browser

MASP1 protein, human Chemical MeSH Browser

MASP2 protein, human Chemical MeSH Browser

Masp1 protein, rat Chemical MeSH Browser

Masp2 protein, rat Chemical MeSH Browser

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