Ataxia Telangiectasia Mutated Proteins [ATM protein]

topical
89
Terms

ATM - protein
protein ataxia telangiectasia mutated
protein ATM

 

A-T Protein
AT Mutated Protein
ATM Protein

Persistent link   https://www.medvik.cz/link/D064007
Definition

A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.

DUI
D064007 MeSH Browser
CUI
M0248389
RN
EC 2.7.11.1
History note
2014
Public note
2014; was indexed under PROTEIN KINASES 1983-1992; PROTEIN-SERINE-THREONINE KINASES 1993-2013

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 0
AN
analysis 1
AI
antagonists & inhibitors 13
BI
biosynthesis 0
BL
blood 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 0
CL
classification 0
DF
deficiency 2
DE
drug effects 0
EC
economics 0
GE
genetics 32
HI
history 0
IM
immunology 1
IP
isolation & purification 1
ME
metabolism 34
PK
pharmacokinetics 0
PD
pharmacology 0
PH
physiology 3
PO
poisoning 0
RE
radiation effects 2
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 1
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) 32
D08.811.913.696.620.682 Protein Kinases 247
D08.811.913.696.620.682.700 Protein Serine-Threonine Kinases 271
D08.811.913.696.620.682.700.062 Activin Receptors 5
D08.811.913.696.620.682.700.074 AMP-Activated Protein Kinase Kinases 1
D08.811.913.696.620.682.700.085 AMP-Activated Protein Kinases 41
D08.811.913.696.620.682.700.097 Ataxia Telangiectasia Mutated Proteins 89
D08.811.913.696.620.682.700.103 Aurora Kinases 4
D08.811.913.696.620.682.700.108 Autophagy-Related Protein-1 Homolog
D08.811.913.696.620.682.700.109 Bone Morphogenetic Protein Receptors 3
D08.811.913.696.620.682.700.125 Calcium-Calmodulin-Dependent Protein Kinases 10
D08.811.913.696.620.682.700.140 Casein Kinases 1
D08.811.913.696.620.682.700.143 Checkpoint Kinase 1 19
D08.811.913.696.620.682.700.145 Checkpoint Kinase 2 49
D08.811.913.696.620.682.700.150 Cyclic Nucleotide-Regulated Protein Kinases
D08.811.913.696.620.682.700.250 DNA-Activated Protein Kinase 14
D08.811.913.696.620.682.700.275 Doublecortin-Like Kinases
D08.811.913.696.620.682.700.288 Dyrk Kinases
D08.811.913.696.620.682.700.300 eIF-2 Kinase 8
D08.811.913.696.620.682.700.364 G-Protein-Coupled Receptor Kinases 2
D08.811.913.696.620.682.700.397 Germinal Center Kinases 2
D08.811.913.696.620.682.700.429 Glycogen Synthase Kinases
D08.811.913.696.620.682.700.494 I-kappa B Kinase 9
D08.811.913.696.620.682.700.526 Interleukin-1 Receptor-Associated Kinases 3
D08.811.913.696.620.682.700.534 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 2
D08.811.913.696.620.682.700.542 Lim Kinases 2
D08.811.913.696.620.682.700.559 MAP Kinase Kinase Kinases 48
D08.811.913.696.620.682.700.565 Mitogen-Activated Protein Kinase Kinases 39
D08.811.913.696.620.682.700.567 Mitogen-Activated Protein Kinases 100
D08.811.913.696.620.682.700.576 Myotonin-Protein Kinase 2
D08.811.913.696.620.682.700.579 NF-kappaB-Inducing Kinase 1
D08.811.913.696.620.682.700.581 NIMA-Related Kinases 4
D08.811.913.696.620.682.700.586 Oncogene Protein v-akt 5
D08.811.913.696.620.682.700.596 p21-Activated Kinases 9
D08.811.913.696.620.682.700.606 Phytochrome A 2
D08.811.913.696.620.682.700.616 Polo-like Kinases
D08.811.913.696.620.682.700.626 Positive Transcriptional Elongation Factor B 4
D08.811.913.696.620.682.700.646 Proline-Directed Protein Kinases 1
D08.811.913.696.620.682.700.725 Protein Kinase C 138
D08.811.913.696.620.682.700.745 3-Phosphoinositide-Dependent Protein Kinases
D08.811.913.696.620.682.700.750 Protein Kinase D2
D08.811.913.696.620.682.700.755 Proto-Oncogene Proteins c-akt 113
D08.811.913.696.620.682.700.759 Proto-Oncogene Proteins c-bcr 19
D08.811.913.696.620.682.700.776 Proto-Oncogene Proteins c-pim-1 1
D08.811.913.696.620.682.700.783 Pyruvate Dehydrogenase Acetyl-Transferring Kinase
D08.811.913.696.620.682.700.789 Receptor, Transforming Growth Factor-beta Type I 2
D08.811.913.696.620.682.700.795 Receptor, Transforming Growth Factor-beta Type II
D08.811.913.696.620.682.700.801 Receptor-Interacting Protein Serine-Threonine Kinases 7
D08.811.913.696.620.682.700.814 rho-Associated Kinases 26
D08.811.913.696.620.682.700.862 Ribosomal Protein S6 Kinases 1
D08.811.913.696.620.682.700.897 Serine-Threonine Kinase 3
D08.811.913.696.620.682.700.931 TOR Serine-Threonine Kinases 193
D08.811.913.696.620.682.700.965 Vacuolar Sorting Protein VPS15
D08.811.913.696.620.682.700.982 WNK Lysine-Deficient Protein Kinase 1
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 575
D12.776.157 Carrier Proteins 546
D12.776.157.687 Poly-ADP-Ribose Binding Proteins 5
D12.776.157.687.063 Apoptosis Inducing Factor 9
D12.776.157.687.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.157.687.157 CCCTC-Binding Factor 2
D12.776.157.687.173 Centromere Protein A 2
D12.776.157.687.188 Centromere Protein B
D12.776.157.687.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.157.687.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.157.687.375 DNA Topoisomerases, Type I 24
D12.776.157.687.438 DNA-Activated Protein Kinase 14
D12.776.157.687.450 Heat Shock Transcription Factors 1
D12.776.157.687.462 Heterogeneous Nuclear Ribonucleoprotein A1
D12.776.157.687.485 Histones 366
D12.776.157.687.493 Ku Autoantigen 5
D12.776.157.687.495 MRE11 Homologue Protein 6
D12.776.157.687.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.157.687.497 NF-kappa B p52 Subunit 2
D12.776.157.687.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.157.687.575 Nitric Oxide Synthase Type II 75
D12.776.157.687.613 Telomerase 189
D12.776.157.687.650 Tumor Suppressor Protein p53 754
D12.776.157.687.750 Werner Syndrome Helicase 2
D12.776.157.687.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.157.687.875 Xeroderma Pigmentosum Group A Protein 2
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.563 Protein Serine-Threonine Kinases 271
D12.776.476.563.062 Activin Receptors 5
D12.776.476.563.074 AMP-Activated Protein Kinase Kinases 1
D12.776.476.563.085 AMP-Activated Protein Kinases 41
D12.776.476.563.097 Ataxia Telangiectasia Mutated Proteins 89
D12.776.476.563.103 Aurora Kinases 4
D12.776.476.563.108 Autophagy-Related Protein-1 Homolog
D12.776.476.563.109 Bone Morphogenetic Protein Receptors 3
D12.776.476.563.125 Calcium-Calmodulin-Dependent Protein Kinases 10
D12.776.476.563.140 Casein Kinases 1
D12.776.476.563.143 Checkpoint Kinase 1 19
D12.776.476.563.145 Checkpoint Kinase 2 49
D12.776.476.563.150 Cyclic Nucleotide-Regulated Protein Kinases
D12.776.476.563.250 DNA-Activated Protein Kinase 14
D12.776.476.563.275 Doublecortin-Like Kinases
D12.776.476.563.288 Dyrk Kinases
D12.776.476.563.300 eIF-2 Kinase 8
D12.776.476.563.364 G-Protein-Coupled Receptor Kinases 2
D12.776.476.563.397 Germinal Center Kinases 2
D12.776.476.563.429 Glycogen Synthase Kinases
D12.776.476.563.494 I-kappa B Kinase 9
D12.776.476.563.526 Interleukin-1 Receptor-Associated Kinases 3
D12.776.476.563.534 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 2
D12.776.476.563.542 Lim Kinases 2
D12.776.476.563.554 MAP Kinase Kinase Kinases 48
D12.776.476.563.565 Mitogen-Activated Protein Kinase Kinases 39
D12.776.476.563.567 Mitogen-Activated Protein Kinases 100
D12.776.476.563.576 Myotonin-Protein Kinase 2
D12.776.476.563.579 NF-kappaB-Inducing Kinase 1
D12.776.476.563.581 NIMA-Related Kinases 4
D12.776.476.563.586 Oncogene Protein v-akt 5
D12.776.476.563.596 p21-Activated Kinases 9
D12.776.476.563.606 Phytochrome A 2
D12.776.476.563.616 Polo-like Kinases
D12.776.476.563.626 Positive Transcriptional Elongation Factor B 4
D12.776.476.563.646 Proline-Directed Protein Kinases 1
D12.776.476.563.725 Protein Kinase C 138
D12.776.476.563.745 3-Phosphoinositide-Dependent Protein Kinases
D12.776.476.563.750 Protein Kinase D2
D12.776.476.563.755 Proto-Oncogene Proteins c-akt 113
D12.776.476.563.759 Proto-Oncogene Proteins c-bcr 19
D12.776.476.563.776 Proto-Oncogene Proteins c-pim-1 1
D12.776.476.563.783 Pyruvate Dehydrogenase Acetyl-Transferring Kinase
D12.776.476.563.789 Receptor, Transforming Growth Factor-beta Type I 2
D12.776.476.563.795 Receptor, Transforming Growth Factor-beta Type II
D12.776.476.563.801 Receptor-Interacting Protein Serine-Threonine Kinases 7
D12.776.476.563.814 rho-Associated Kinases 26
D12.776.476.563.862 Ribosomal Protein S6 Kinases 1
D12.776.476.563.897 Serine-Threonine Kinase 3
D12.776.476.563.931 TOR Serine-Threonine Kinases 193
D12.776.476.563.965 Vacuolar Sorting Protein VPS15
D12.776.476.563.982 WNK Lysine-Deficient Protein Kinase 1
D12.776.660 Nuclear Proteins 451
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.720.063 Apoptosis Inducing Factor 9
D12.776.660.720.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.660.720.157 CCCTC-Binding Factor 2
D12.776.660.720.173 Centromere Protein A 2
D12.776.660.720.188 Centromere Protein B
D12.776.660.720.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.660.720.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.660.720.375 DNA Topoisomerases, Type I 24
D12.776.660.720.438 DNA-Activated Protein Kinase 14
D12.776.660.720.462 Heat Shock Transcription Factors 1
D12.776.660.720.485 Histones 366
D12.776.660.720.493 Ku Autoantigen 5
D12.776.660.720.495 MRE11 Homologue Protein 6
D12.776.660.720.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.660.720.497 NF-kappa B p52 Subunit 2
D12.776.660.720.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.660.720.575 Nitric Oxide Synthase Type II 75
D12.776.660.720.613 Telomerase 189
D12.776.660.720.650 Tumor Suppressor Protein p53 754
D12.776.660.720.750 Werner Syndrome Helicase 2
D12.776.660.720.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.660.720.875 Xeroderma Pigmentosum Group A Protein 2

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