Streptococcus pneumoniae causes considerable global paediatric morbidity and mortality, despite the availability of safe and effective pneumococcal conjugate vaccines (PCVs). To justify the introduction of PCVs, accurate information on the burden of disease is required. Here, we present an appraisal of the pneumococcal epidemiological situation in 11 Central European countries. The data are based on study findings presented at the 12th Central European Vaccine Advisory Group (CEVAG) meeting, held on 21-22 May 2010 in Sofia, Bulgaria, and a literature review of the PubMed database using the search terms 'pneumococcal' or 'Streptococcus pneumoniae', in combination with 'otitis media', 'pneumonia', 'meningitis' or 'bacteraemia/sepsis', and '[Central European country name]'. The incidence of pneumococcal disease appears to be lower in Central Europe than previously reported for Europe as a whole, with the highest risk in infants aged 0-2 years. The fatality rates in the under fives from invasive infections are up to 40%. A paucity of comprehensive country-specific data on pneumococcal disease burden arises from the lack of homogenous surveillance programmes. Standardised, active surveillance systems are required for the accurate evaluation of the pneumococcal disease burden in the region. Only then can the need for vaccination be addressed.
- MeSH
- dítě MeSH
- imunizace MeSH
- incidence MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- otitis media epidemiologie imunologie mikrobiologie prevence a kontrola MeSH
- pneumokoková meningitida epidemiologie imunologie mikrobiologie prevence a kontrola MeSH
- pneumokokové vakcíny aplikace a dávkování MeSH
- pneumonie pneumokoková epidemiologie imunologie mikrobiologie prevence a kontrola MeSH
- předškolní dítě MeSH
- sepse epidemiologie imunologie mikrobiologie prevence a kontrola MeSH
- sérotypizace MeSH
- Streptococcus pneumoniae * klasifikace imunologie MeSH
- vakcíny konjugované aplikace a dávkování MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Geografické názvy
- Evropa MeSH
