- Klíčová slova
- virové gastroenteritidy,
- MeSH
- adenovirové infekce diagnóza přenos terapie MeSH
- gastroenteritida * etiologie virologie MeSH
- infekce viry z čeledi Caliciviridae diagnóza přenos terapie MeSH
- lidé MeSH
- rotavirové infekce diagnóza přenos terapie MeSH
- Rotavirus patogenita MeSH
- tekutinová terapie metody MeSH
- vakcína proti rotavirům terapeutické užití MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
Human adenoviruses (HAdV; species HAdV-A to -G) are highly prevalent in the human population, and represent an important cause of morbidity and, to a lesser extent, mortality. Recent studies have identified close relatives of these viruses in African great apes, suggesting that some HAdV may be of zoonotic origin. We analyzed more than 800 fecal samples from wild African great apes and humans to further investigate the evolutionary history and zoonotic potential of hominine HAdV. HAdV-B and -E were frequently detected in wild gorillas (55%) and chimpanzees (25%), respectively. Bayesian ancestral host reconstruction under discrete diffusion models supported a gorilla and chimpanzee origin for these viral species. Host switches were relatively rare along HAdV evolution, with about ten events recorded in 4.5 My. Despite presumably rare direct contact between sympatric populations of the two species, transmission events from gorillas to chimpanzees were observed, suggesting that habitat and dietary overlap may lead to fecal-oral cross-hominine transmission of HAdV. Finally, we determined that two independent HAdV-B transmission events to humans occurred more than 100,000 years ago. We conclude that HAdV-B circulating in humans are of zoonotic origin and have probably affected global human health for most of our species lifetime.
- MeSH
- Adenoviridae * genetika patogenita MeSH
- adenovirové infekce * genetika přenos MeSH
- druhová specificita MeSH
- Hominidae virologie MeSH
- lidé MeSH
- molekulární evoluce * MeSH
- zoonózy genetika přenos MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Two cases of polyradiculoneuritis in children were noted during January, 1984. Each girl was a member of a different group of children: the first group was newly constituted of children from various remote regions of Czechoslovakia in a Medical Institution, the second one included children attending the same nursery school for a long time. In both groups, all or most of the children went through one or two respiratory infections which preceded the development of a paralytic disease. From the first girl, coxsackievirus A9 was recovered in nasopharyngeal swabs and in a stool sample. Among contacts in the Children's Medical Institution, a concurrent circulation of this enterovirus and of an adenovirus type 3 was demonstrated by isolation attempts and confirmed by serological examinations. From the second girl, coxsackie A9 and an adenovirus type 29 were demonstrated in the same stool sample and a simultaneous circulation of both virus species among the nursery school and family contacts was proved by isolation attempts and by serological investigations. The concurrent, overlapping or sequential circulation of adenoviruses and enteroviruses may perhaps contribute to a compromised immunity resulting in a manifestation of paralysis.
- MeSH
- adenovirové infekce lidí mikrobiologie přenos MeSH
- adenovirové infekce přenos MeSH
- coxsackie virózy mikrobiologie přenos MeSH
- Enterovirus izolace a purifikace MeSH
- feces mikrobiologie MeSH
- lidé MeSH
- lidské adenoviry izolace a purifikace MeSH
- nazofarynx mikrobiologie MeSH
- polyradikuloneuropatie mikrobiologie přenos MeSH
- předškolní dítě MeSH
- Check Tag
- lidé MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Geografické názvy
- Československo MeSH
Acta hygienica, epidemiologica et microbiologica ; Příl. [R.] 1984. č. 7
29 l. : tab. ; 29 cm
- MeSH
- adenovirové infekce diagnóza prevence a kontrola přenos MeSH
- antigeny virové MeSH
- diferenciální diagnóza MeSH
- fluorescenční protilátková technika MeSH
- imunoelektronová mikroskopie MeSH
- klinické laboratorní techniky metody normy MeSH
- lidské adenoviry izolace a purifikace MeSH
- odběr biologického vzorku MeSH
- sérologické testy MeSH
- Publikační typ
- směrnice MeSH
- Geografické názvy
- Česká republika MeSH
- Slovenská republika MeSH
- Konspekt
- Mikrobiologie
- NLK Obory
- chemie, klinická chemie
- infekční lékařství
- virologie