The goal of study was to explore the role of 3D CBCT (cone beam computer tomography) in detecting impacted canines and their movement to evaluate the influence of orthodontic therapy parameters on treatment options, and to monitor quality of healing process based on shape and size of sinus maxillae volume. It is known that the volume of maxillary sinus plays an important role in patients with impacted teeth. The prospective study consisted of 26 individuals. For each individual, pre-treatment and post-treatment CBCT data were acquired. Changes of size, and position of impacted canine in 3D CBCT image before and after therapy were prepared using 3D reconstruction. Volumetric measurements of the maxillary sinuses were performed before and after orthodontic therapy of impacted canines, using InVivo6 software. The main effects MANOVA performed on linear measurements showed metric differences between pre-op and post-op images. A paired t-test showed no statistically significant differences between pre-op and post-op values of the sinus volume. Changes of size and position of impacted canine in 3D image before and after therapy were precise and reproducible, using 3D reconstruction in three planes - horizontal, midsagittal, and coronal. The linear measurements showed metric differences between pre-op and post-op images.
- MeSH
- Humans MeSH
- Cone-Beam Computed Tomography methods MeSH
- Prospective Studies MeSH
- Maxillary Sinus diagnostic imaging MeSH
- Cuspid diagnostic imaging MeSH
- Tooth, Impacted * diagnostic imaging therapy MeSH
- Imaging, Three-Dimensional methods MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
BACKGROUND: Low-grade fibromyxoid sarcoma (LGFMS) is a rare malignant tumor. Moreover, only 3 cases of LGFMS originating from the nasal cavity and/or paranasal sinuses have been published so far. METHODS: Two patients with histologically confirmed LGFMS of the maxillary sinus were primarily treated by open and endoscopic surgery. In one case adjuvant radiotherapy was indicated because of the uncertainty of the surgical margins. RESULTS: Both surgeries were technically demanding and accompanied by significant bleeding from the tumors. Despite the extensive interventions there were no postoperative complications and no significant morbidity of the patients. There is no evidence of the disease 148 and 65 months after the treatment. CONCLUSIONS: Regardless of the excellent post-treatment results, based on our experience, preoperative embolisation of the tumor should be considered prior to the surgical resection.
- MeSH
- Fibrosarcoma * MeSH
- Humans MeSH
- Maxillary Sinus * diagnostic imaging surgery MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
SUMMARY: Skin is one of the target tissues of rejection in face transplants and, because of its easy accessibility, has become the gold standard in the diagnosis of rejection. The allograft contains deeper tissues where rejection can occur, but samples cannot be obtained because of difficult access. Deep tissue changes were monitored on computed tomographic scans of the midface in six face transplant recipients with the help of image segmentation. The maxillary sinus was identified as a dynamic anatomical compartment. Observed changes in volume of the aeration relative to the opacification (aeration coefficient) of the maxillary sinus were quantified with the help of image segmentation. Changes in the aeration coefficient as a surrogate of mucosal swelling were quantified and related to time, treatment, and skin rejection grade. Lower aeration coefficients were found only in patients with transplanted maxillary sinus mucosa. Pathologic changes were not observed in face transplant recipients with a native maxillary sinus. The data show that the aeration coefficient was significantly lower at the time of biopsy-proven allograft rejection. Neither mechanical, nor infectious, nor medication side effects sufficiently explain the findings presented herein. The authors' findings are important to consider for clinical management of face transplant patients who receive parts of the sinonasal tract. The authors identify a potential radiologic biomarker of deep tissue allograft rejection. In the future, the proposed methodology might prove useful in monitoring deeper dynamic tissue changes in vascularized composite allografts and might help in designing patient-specific, individualized treatment strategies.
- MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Tomography, X-Ray Computed MeSH
- Graft Rejection diagnosis etiology pathology prevention & control MeSH
- Respiratory Mucosa pathology transplantation MeSH
- Retrospective Studies MeSH
- Maxillary Sinus diagnostic imaging pathology MeSH
- Composite Tissue Allografts diagnostic imaging pathology MeSH
- Facial Transplantation adverse effects MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- MeSH
- Humans MeSH
- Follow-Up Studies MeSH
- Radiography MeSH
- Reference Values MeSH
- Maxillary Sinus diagnostic imaging surgery MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
