Cíl. Cooper-Norcross Inventory of Preferences (C-NIP) představuje nejnovější a slibný nástroj určený k měření preferencí klientů ve vztahu k psychoterapii. Psychometrické zhodnocení tohoto nástroje je však zatím sporé a u české verze zcela chybí. Cílem této studie bylo ověřit faktorovu strukturu české verze C-NIP, ověřit invarianci měření a stanovit hraniční skóry. Metody. N = 772 dospělých respondentů vyplnilo C-NIP v online průzkumu. K ověření faktorové struktury a invariance měření mezi pohlavími a napříč různými úrovněmi zkušenosti s psychoterapií byla použita konfirmační faktorový analýza. Výsledky. Původní faktorová struktura nebyla podpořena. Namísto toho byl navržen pětifaktorový model, který vykazoval adekvátní shodu s daty a byl striktně invariantní ve vztahu k pohlaví i úrovni zkušenosti s psychoterapií. Závěr. Českou verzi C-NIP lze považovat za validní a reliabilní nástroj na měření preferencí klientů ve vztahu k psychoterapii. Je zapotřebí replikovat navrženou faktorovou strukturu.

Objective. The Cooper-Norcross Inventory of Preferences (C-NIP) is a new and promising tool for measuring clients’ preferences regarding psychotherapy. However, the psychometric evaluation of this measure is scarce in general and completely missing for the Czech adaptation of the measure. This study aimed to test the Czech version of the C-NIP factor structure, test its measurement invariance, and establish cut points. Methods. N = 772 adults answered the C-NIP in an online survey. Confirmatory and exploratory factor analyses were used to test the factor structure and assess the C-NIP measurement invariance between men and women and across several levels of psychotherapy experience. Results. The original four-factor model was not supported. Instead, a five-factor model was suggested that fit the data adequately and was strictly invariant with respect to gender and levels of experience with psychotherapy. Conclusions. The Czech C-NIP can be considered a valid and reliable measure of clients’ preferences regarding psychotherapy. The replication of the new factor model is needed.

OBJECTIVE: The Cooper-Norcross Inventory of Preferences (C-NIP) is a brief, multidimensional measure of clients' therapy preferences. This study aimed to examine the factor structure and measurement invariance of the C-NIP. METHOD: Fifteen datasets (N = 10,088 observations) representing the C-NIP in nine language versions were obtained from authors of psychometric studies. Confirmatory factor analysis and exploratory structural equation modeling were used to analyze the data. RESULTS: None of the proposed models adequately fit the data. Therefore, a new model was developed that sufficiently fit most of the C-NIP version 1.1 datasets. The new model was invariant up to the strict and means levels across genders, ages, and psychotherapy experience but only up to the metric level across translations. CONCLUSIONS: The C-NIP can be used to compare men and women, people of diverse ages, and people with some vs. no experience with psychotherapy. Lower reliabilities of the C-NIP scales are a limitation.

• MeSH
• Adult MeSH
• Factor Analysis, Statistical MeSH
• Middle Aged MeSH
• Humans MeSH
• Young Adult MeSH
• Patient Preference MeSH
• Psychometrics * instrumentation   standards   MeSH
• Psychotherapy * standards   MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH

• MeSH
• Lipids MeSH
• Lipid Metabolism MeSH
• Publication type
• Abstracts MeSH
• Congress MeSH
• Collected Work MeSH
• News MeSH

• Conspectus
• Biochemie. Molekulární biologie. Biofyzika
• NML Fields
• biochemie
• fyziologie

• MeSH
• Infant, Newborn, Diseases MeSH
• Neonatology MeSH
• Pediatrics MeSH
• Perinatal Care MeSH
• Publication type
• Monograph MeSH

• Conspectus
• Pediatrie
• NML Fields
• pediatrie
• perinatologie a neonatologie

Tissue engineering benefits from novel materials with precisely tunable physical, chemical and mechanical properties over a broad range. Here we report a practical approach to prepare Bombyx mori silk fibroin hydrogels using the principle of non-solvent induced phase separation (NIPS). A combination of reconstituted silk fibroin (RSF) and methanol (non-solvent), with a final concentration of 2.5% w/v and 12.5% v/v respectively, maintained at 22 °C temperature turned into a hydrogel within 10 hours. Freeze-drying of this gel gave a foam with a porosity of 88%, a water uptake capacity of 89% and a swelling index of 8.6. The gelation kinetics and the loss tangent of the gels were investigated by rheometry. The changes in the morphology of the porous foams were visualized by SEM. The changes in RSF chemical composition and the relative fraction of its secondary structural elements were analyzed by ATR-FTIR along with Fourier self-deconvolution. And, the changes in the glass transition temperature, specific heat capacity and the relative fraction of crystallinity of RSF were determined by TM-DSC. Data suggested that RSF-water-methanol behaved as a polymer-solvent-non-solvent ternary phase system, wherein the demixing of the water-methanol phases altered the thermodynamic equilibrium of RSF-water phases and resulted in the desolvation and eventual separation of the RSF phase. Systematic analysis revealed that both gelation time and the properties of hydrogels and porous foams could be controlled by the ratios of RSF and non-solvent concentration as well as by the type of non-solvent and incubation temperature. Due to the unique properties we envisage that the herein prepared NIPS induced RSF hydrogels and porous foams can possibly be used for the encapsulation of cells and/or for the controlled release of both hydrophilic and hydrophobic drugs.

• MeSH
• Biocompatible Materials chemistry   MeSH
• Bombyx chemistry   MeSH
• Fibroins chemistry   MeSH
• Hydrophobic and Hydrophilic Interactions MeSH
• Hydrogels chemistry   MeSH
• Porosity MeSH
• Solvents chemistry   MeSH
• Temperature MeSH
• Tissue Engineering MeSH
• Animals MeSH
• Check Tag
• Animals MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH

BACKGROUND: The aim of our study was to compare the analgesic/sedative effects of various fundus-related procedural pain management strategies on the risk of retinopathy in premature infants. METHOD: This was a prospective comparative study involving a total of 94 neonates randomized to three groups meeting the criteria for at-risk neonates. Ophthalmologic screening was performed to evaluate the outcome of three procedural pain management strategies. The intensity of pain over time during and after the screening examination was evaluated. At the same time, we also looked at the occurrence of vegetative symptoms and their influence by the chosen medication. Pain response was observed in all 94 neonates enrolled in the study. In group A, no pain treatment was given. Group B had a local anesthetic oxybuprocaine hydrochloride 0.4% introduced into both eyes immediately prior to the examination. Group C received oral clonidine. The study was conducted as a pilot project and aimed to clarify the problem so that a project with a higher proband representation could take place in the future. Consequently, we performed quantitative analysis of complete pain and vegetative functions, followed by a qualitative analysis of their internal components. RESULTS: In our study, we identified the most considerable effects for all three groups, including NIPS (Neonatal Infant Pain Scale) responses immediately during and after the examination. The influence of vegetative functions is of a longer-term nature and increased values can be clearly demonstrated even six hours after the examination. CONCLUSION: The current results identify and quantify differences among all three methods of pain treatment on the level of single variables. Their internal structures, however, can be analysed only qualitatively because of the small size of the analysed sample.

• Publication type
• Journal Article MeSH

• MeSH
• Dispensatories as Topic MeSH
• Homeopathy MeSH
• Pharmaceutical Preparations MeSH
• Publication type
• Handbook MeSH

• Conspectus
• Fyzioterapie. Psychoterapie. Alternativní lékařství
• NML Fields
• homeopatie