• MeSH
• epidemiologické studie MeSH
• epilepsie genetika   MeSH
• genetická predispozice k nemoci * epidemiologie   genetika   MeSH
• komplikace těhotenství MeSH
• lidé MeSH
• matka - expozice noxám klasifikace   škodlivé účinky   MeSH
• metabolické nemoci genetika   MeSH
• novorozenec s nízkou porodní hmotností MeSH
• novorozenec MeSH
• průzkumy a dotazníky MeSH
• rozštěp patra * etiologie   genetika   MeSH
• rozštěp rtu * etiologie   genetika   MeSH
• statistika jako téma MeSH
• životní prostředí MeSH
• Check Tag
• lidé MeSH
• novorozenec MeSH
• Geografické názvy
• Itálie MeSH

The Trypanosoma theileri group includes several trypanosome species hardly distinguishable due to the lack of discriminating morphological characters. Trypanosomes belonging to this group have been isolated from different bovine, ovine, and cervids in Europe, Africa, Asia, and Americas. The principal vectors of the T. theileri group are considered tabanid flies; however, T. melophagium is transmitted exclusively by sheep keds. In 2016, 128 sand flies out of 2,728 trapped in Valsamoggia municipality, Italy, were individually dissected and an unknown trypanosome strain, named TrPhp1, was isolated from a female of the sand fly Phlebotomus perfiliewi. Sequence analysis placed this trypanosome in the T. theileri group with very high homology to other trypanosomes detected in European cervids. This is the first report of the T. theileri group isolation from a sand fly, and the possible role of this insect group in the trypanosome transmission cycle is discussed. Within the T. theileri group, the phylogenetic analysis distinguished several lineages, which, unfortunately, do not correspond with their host specificity and their taxonomic status remains ambiguous.

• MeSH
• Diptera MeSH
• fylogeneze MeSH
• hmyz - vektory MeSH
• ovce MeSH
• Phlebotomus parazitologie   MeSH
• protozoální DNA analýza   MeSH
• Psychodidae MeSH
• Trypanosoma izolace a purifikace   MeSH
• Trypanosomatina MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Itálie MeSH

INTRODUCTION: Published prevalence rates of congenital diaphragmatic hernia (CDH) vary. This study aims to describe the epidemiology of CDH using data from high-quality, population-based registers belonging to the European Surveillance of Congenital Anomalies (EUROCAT). METHODS: Cases of CDH delivered between 1980 and 2009 notified to 31 EUROCAT registers formed the population-based case series. Prevalence over time was estimated using multilevel Poisson regression, and heterogeneity between registers was evaluated from the random component of the intercept. RESULTS: There were 3373 CDH cases reported among 12 155 491 registered births. Of 3131 singleton cases, 353 (10.4%) were associated with a chromosomal anomaly, genetic syndrome or microdeletion, 784 (28.2%) were associated with other major structural anomalies. The male to female ratio of CDH cases overall was 1:0.69. Total prevalence was 2.3 (95% CI 2.2 to 2.4) per 10 000 births and 1.6 (95% CI 1.6 to 1.7) for isolated CDH cases. There was a small but significant increase (relative risk (per year)=1.01, 95% credible interval 1.00-1.01; p=0.030) in the prevalence of total CDH over time but there was no significant increase for isolated cases (ie, CDH cases that did not occur with any other congenital anomaly). There was significant variation in total and isolated CDH prevalence between registers. The proportion of cases that survived to 1 week was 69.3% (1392 cases) for total CDH cases and 72.7% (1107) for isolated cases. CONCLUSIONS: This large population-based study found an increase in total CDH prevalence over time. CDH prevalence also varied significantly according to geographical location. No significant association was found with maternal age.

• MeSH
• analýza přežití MeSH
• dospělí MeSH
• gestační stáří MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mnohočetné abnormality epidemiologie   MeSH
• novorozenec MeSH
• porodní hmotnost MeSH
• prevalence MeSH
• registrace MeSH
• surveillance populace MeSH
• věk matky MeSH
• vrozená brániční kýla epidemiologie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• novorozenec MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Evropa MeSH