Human-induced rapid environmental change
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The rapid evolution of technologies is a key innovation in the organisation and management of physical activities (PA) and sports. The increase in benefits and opportunities related to the adoption of technologies for both the promotion of a healthy lifestyle and the management of chronic diseases is evident. In the field of telehealth, these devices provide personalised recommendations, workout monitoring and injury prevention. The study aimed to provide an overview of the landscape of technology application to PA organised to promote active lifestyles and improve chronic disease management. This review identified specific areas of focus for the selection of articles: the utilisation of mobile APPs and technological devices for enhancing weight loss, improving cardiovascular health, managing diabetes and cancer and preventing osteoporosis and cognitive decline. A multifactorial intervention delivered via mobile APPs, which integrates PA while managing diet or promoting social interaction, is unquestionably more effective than a singular intervention. The main finding related to promoting PA and a healthy lifestyle through app usage is associated with "behaviour change techniques". Even when individuals stop using the APP, they often maintain the structured or suggested lifestyle habits initially provided by the APP. Various concerns regarding the excessive use of APPs need to be addressed.
- MeSH
- behaviorální terapie MeSH
- cvičení psychologie MeSH
- dieta MeSH
- lidé MeSH
- mobilní aplikace * MeSH
- telemedicína * MeSH
- životní styl MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
... THE PHYSIOLOGICAL BASIS OF HUMAN SLEEP 24 -- Subcortical regulation of human sleep 24 -- Consciousness ... ... , baroceptor impulses and respiration 26 -- The carotid sinus and human sleep-reactions 28 -- Corticofugal ... ... influences on the human reticular formation 29 -- / CHAPTER IV. ... ... 75 -- Imagery 76 -- Environmental uniformity 78 -- Images are constructions derived from hidden meaning ... ... SOME PHYSIOLOGICAL FUNCTIONS -- Changes with sleep -- The respiration -- The need for sleep -- Rhythms ...
ix, 232 stran : ilustrace ; 23 cm
- MeSH
- bdění fyziologie MeSH
- spánek fyziologie MeSH
- Publikační typ
- monografie MeSH
- Konspekt
- Psychologie
- NLK Obory
- psychologie, klinická psychologie
Several studies have demonstrated that zinc is required for the optimal functioning of the skin. Changes in intracellular zinc concentrations have been associated with both improved protection of skin cells against various noxious factors as well as with increased susceptibility to external stress. Still, little is known about the role of intracellular zinc in hexavalent chromium (Cr(VI))-induced skin injury. To address this question, the effects of zinc deficiency or supplementation on Cr(VI)-induced cytotoxicity, oxidative stress, DNA injury and cell death were investigated in human diploid dermal fibroblasts during 48 h. Zinc levels in fibroblasts were manipulated by pretreatment of cells with 100 microM ZnSO4 and 4 or 25 microM zinc chelator TPEN. Cr(VI) (50, 10 and 1 microM) was found to produce time- and dose-dependent cytotoxicity resulting in oxidative stress, suppression of antioxidant systems and activation of p53-dependent apoptosis which is reported for the first time in this model in relation to environmental Cr(VI). Increased intracellular zinc partially attenuated Cr(VI)-induced cytotoxicity, oxidative stress and apoptosis by enhancing cellular antioxidant systems while inhibiting Cr(VI)-dependent apoptosis by preventing the activation of caspase-3. Decreased intracellular zinc enhanced cytotoxic effects of all the tested Cr(VI) concentrations, leading to rapid loss of cell membrane integrity and nuclear dispersion--hallmarks of necrosis. These new findings suggest that Cr(VI) as a model environmental toxin may damage in deeper regions residing skin fibroblasts whose susceptibility to such toxin depends among others on their intracellular Zn levels. Further investigation of the impact of Zn status on skin cells as well as any other cell populations exposed to Cr(VI) or other heavy metals is warranted.
- MeSH
- antioxidancia metabolismus MeSH
- apoptóza účinky záření MeSH
- buněčná membrána účinky léků MeSH
- chrom farmakologie MeSH
- DNA biosyntéza MeSH
- fibroblasty cytologie účinky léků MeSH
- financování organizované MeSH
- glutathionperoxidasa metabolismus MeSH
- glutathionreduktasa metabolismus MeSH
- kaspasa 3 MeSH
- kaspasy metabolismus MeSH
- kultivované buňky MeSH
- lidé MeSH
- metalothionein metabolismus MeSH
- nádorový supresorový protein p53 metabolismus MeSH
- oxidační stres účinky záření MeSH
- poškození DNA genetika účinky léků MeSH
- proliferace buněk účinky léků MeSH
- škára cytologie účinky léků MeSH
- viabilita buněk účinky léků MeSH
- zinek metabolismus MeSH
- Check Tag
- lidé MeSH
... Hunsmann 250 -- Vaginal and rectal immunization against AIDS in non-human and human primates, T. ... ... Sans 457 -- Molecular genetics of human hypertension, F. ... ... Vrensen 594 -- The human haematopoietic stem cell, S. ... ... HUMAN GENOME ANALYSIS -- Introduction, M. ... ... Edgar 696 -- Fertility, infertility and the human embryo ethics, law and practice of human artificial ...
Biomedical and health research, ISSN 0929-6743 vol. 9
xxxix, 744 s. ; 24 cm
... CHANGES -- Chapter 32 Sensory Systems Chapter 33 The Immune System Chapter 34 Molecular Motors -- « ... ... and the Laws of Thermodynamics -- 1.3.4 Protein Folding Can Be Understood in Terms of Free-Energy Changes ... ... -- 1.4 Biochemistry and Human Biology -- Appendix: Depicting Molecular Structures -- 6 6 -- 10 -- 11 ... ... -- Requires the Orchestrated Differentiation of Cells 36 -- 2.4.4 The Unity of Biochemistry Allows Human ... ... Substantial Structural Changes at the Iron Sites in Hemoglobin 270 -- Contents XXV -- 10.2.2 Oxygen ...
5th ed. xvii, 974 s. : il., tab., grafy ; 32 cm
... barriers are the first defense against pathogens. 1 -3 The immune system is activated by inflammatory inducers ... ... recognition receptors that provide an initial discrimination between self and nonself. 1 -6 Sensor cells induce ... ... Principles of adaptive immunity. 1-8 The interaction of antigens with antigen receptors induces lymphocytes ... ... damage. 96 -- 3-9 NLRP proteins react to infection or cellular damage through an inflammasome to induce ... ... shock when released systemically. 118 -- 3-21 Cytokines made by macrophages and dendritic cells induce ...
9th edition xx, 904 stran : ilustrace, tabulky ; 28 cm
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- alergologie a imunologie
- biologie
- fyziologie
- NLK Publikační typ
- kolektivní monografie
... Eukaryotic 1 -- Unicellular Organisms Help and Hurt Us 4 -- Viruses Are the Ultimate Parasites 6 -- Changes ... ... and Move 16 -- Cells Sense and Send Information 16 -- Cells Regulate Their Gene Expression to Meet Changing ... ... Differences in the Structure and Expression of Entire Genomes 23 -- Developmental Biology Reveals Changes ... ... Animals Are Relevant to Genes 28 -- Many Genes Controlling Development Are Remarkably Similar in Humans ... ... and Other Animals 28 -- Human Medicine Is Informed by Research on Other -- Organisms 29 -- 2 CHEMICAL ...
6th ed. xxxvii, 1150 s. : il., tab. ; 29 cm
- MeSH
- biologie buňky MeSH
- molekulární biologie MeSH
- Publikační typ
- monografie MeSH
- Konspekt
- Biochemie. Molekulární biologie. Biofyzika
- NLK Obory
- biologie
- cytologie, klinická cytologie
... , Duffy, Kidd and Other -- Blood Groups 375 -- Hereditary Serum Groups . . 376 -- Blood Groups and Human ... ... The Ethnologic Distribution of Blood -- Groups 377 -- Blood Groups and Human Disease 378 -- Blood Groups ... ... 694 -- Neurologic Manifestations . . . 697 -- Laboratory Findings 697 -- Bone Marrow 701 -- Blood Changes ... ... Cell55 Aplasia 796 -- Symptomatology of the Pancytopenias and Aplastic Anemia . . . 797 -- Blood Changes ... ... Various Environmental Factors . Irradiation -- Leukemia in Other Species. ...
Sixth edition xxv, 1287 stran, 21 nečíslovanýcjh listů obrazové přílohy : ilustrace ; 26 cm
- MeSH
- hematologie MeSH
- krev MeSH
- krevní nemoci MeSH
- Publikační typ
- monografie MeSH
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- hematologie a transfuzní lékařství
... Concepts in Immunology 1 -- Chapter 2 Innate Immunity: The First Lines of Defense 37 -- Chapter 3 The Induced ... ... - Principles of innate and adaptive immunity. 3 -- 1-1 The immune system recognizes infection and induces ... ... tissues throughout the body. 9 -- 1-6 Most infectious agents activate the innate immune system and induce ... ... Section references. 121 -- 122 -- 122 -- Ch apter 3 -- The Induced Responses of Innate -- Immunity 75 ... ... proteins MD-2 and CD14. 88 -- 3-7 TLRs activate the transcription factors NFKB, AP-1, and IRF to induce ...
8th ed. xix, 868 s. : il., tab.
- MeSH
- imunita MeSH
- imunitní systém MeSH
- imunoterapie MeSH
- Publikační typ
- monografie MeSH
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- alergologie a imunologie
- biologie
... 283 -- Fungi Cause Disease in Humans 283 -- Perspective 12.3: The Salem Witch Hunts 284 -- Some Fungi ... ... 324 Three Groups of DNA Viruses Have Been Shown to Cause Tumors in Humans 324 -- Contents -- XV -- A ... ... -- Microorganisms and Humans 331 -- 15 Interactions Between Humans and Microorganisms 332 -- Key Concepts ... ... Body 334 -- Microorganisms and Humans Form a Variety of Symbiotic Relationships 334 -- Establishing ... ... and Maintaining the Normal Flora as a Dynamic Human-Microbe Ecosystem Is Important for Good Health 335 ...
XXVIII, 812 s. : il. ; 32 cm
