Spike latency coding
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Recent studies on the theoretical performance of latency and rate code in single neurons have revealed that the ultimate accuracy is affected in a nontrivial way by aspects such as the level of spontaneous activity of presynaptic neurons, amount of neuronal noise or the duration of the time window used to determine the firing rate. This study explores how the optimal decoding performance and the corresponding conditions change when the energy expenditure of a neuron in order to spike and maintain the resting membrane potential is accounted for. It is shown that a nonzero amount of spontaneous activity remains essential for both the latency and the rate coding. Moreover, the optimal level of spontaneous activity does not change so much with respect to the intensity of the applied stimulus. Furthermore, the efficiency of the temporal and the rate code converge to an identical finite value if the neuronal activity is observed for an unlimited period of time.
- MeSH
- časové faktory MeSH
- energetický metabolismus * MeSH
- lidé MeSH
- membránové potenciály MeSH
- modely neurologické * MeSH
- nervová síť cytologie fyziologie MeSH
- neuronové sítě * MeSH
- neurony fyziologie MeSH
- počítačová simulace MeSH
- výpočetní biologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- kochlea fyziologie inervace MeSH
- lokalizace zvuku fyziologie MeSH
- mozkový kmen cytologie fyziologie MeSH
- reakční čas MeSH
- Publikační typ
- přehledy MeSH
Neuronal response latency is usually vaguely defined as the delay between the stimulus onset and the beginning of the response. It contains important information for the understanding of the temporal code. For this reason, the detection of the response latency has been extensively studied in the last twenty years, yielding different estimation methods. They can be divided into two classes, one of them including methods based on detecting an intensity change in the firing rate profile after the stimulus onset and the other containing methods based on detection of spikes evoked by the stimulation using interspike intervals and spike times. The aim of this paper is to present a review of the main techniques proposed in both classes, highlighting their advantages and shortcomings.
- MeSH
- akční potenciály fyziologie MeSH
- algoritmy * MeSH
- evokované potenciály fyziologie MeSH
- lidé MeSH
- modely neurologické * MeSH
- nervová síť fyziologie MeSH
- neurony fyziologie MeSH
- počítačová simulace MeSH
- reakční čas fyziologie MeSH
- statistické modely MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- srovnávací studie MeSH
... Sensory Nerve Conduction 88 Stimulation and Recording 88 Latency and Conduction Velocity 88 Waveform ... ... F-Wave Analyses 153 Recording and Measurement 153 Distal versus Proximal Stimulation 156 Central Latency ... ... The Silent Period and -- Long-Latency Reflex 219 Silent Period 219 Physiologic Mechanisms 220 Potentials ... ... Relative Refractory Period 242 Paired Shock and Collision Technique 242 Changes in Amplitude versus Latency ... ... Endplate Activities 337 Endplate Noise 337 Endplate Spike 339 -- 5. ...
4th ed. xxix, 1146 s. : il., tab. ; 26 cm + 1 CD-ROM
- MeSH
- elektrodiagnostika metody MeSH
- elektromyografie MeSH
- nemoci míchy diagnóza MeSH
- nervové vedení fyziologie MeSH
- nervový přenos fyziologie MeSH
- neuromuskulární nemoci diagnóza MeSH
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- neurologie
- diagnostika
- NLK Publikační typ
- kolektivní monografie