Úvod: Cílem této studie bylo porovnat dva systémy uzavírání žil kyanoakrylátovým lepidlem, VenaSealTM a VariClose®, v léčbě povrchové žilní insuficience. Metody: Byla provedena retrospektivní analýza pacientů léčených od dubna 2018 do dubna 2022 kyanoakrylátovými lepidly pro insuficienci povrchových žil dolních končetin v jednom centru. Výsledky: Systém VariClose® byl použit u 27 pacientů (30 žil) a systém VenaSealTM u 97 pacientů (125 žil). Medián sledování pacientů léčených systémy VariClose® a VenaSealTM dosahoval 267 (IQR 223) a 201 (IQR 280) dnů. Po roce došlo k rekanalizaci u 11 žil léčených systémem VariClose® a u 5 žil léčených systémem VenaSealTM. Míra okluze odhadnutá Kaplanovou-Meierovou metodou v 30, 90, 180 a 360 dnech činila pro žíly léčené systémem VariClose® 100 %, 96 %, 83 % a 42 % a pro žíly léčené systémem VenaSealTM 100 %, 98 %, 96 % a 91 % (p < 0,01). Závěr: Systém VenaSealTM měl významně lepší míru okluze než systém VariClose®.

Objective: The goal of this study was to compare the cyanoacrylate venous sealing systems VenaSealTM and VariClose® in the treatment of superficial venous insufficiency. Methods: A single-centre retrospective analysis on patients treated between April 2018 and April 2022 with cyanoacrylate adhesives for lower limb superficial truncal vein insufficiency was performed. Results: The VariClose® system was used in 27 patients (30 veins) and the VenaSealTM system in 97 patients (125 veins). The median follow-up periods for patients treated with VariClose® and VenaSealTM systems were 267 (IQR 223) and 201 (IQR 280) days, respectively. At one year, recanalization occurred in 11 veins treated with the VariClose® system and 5 veins treated with the VenaSealTM system. The occlusion rates estimated by the Kaplan-Meier method at 30, 90, 180, and 360 days were 100%, 96%, 83%, and 42% for veins treated with the VariClose® system and 100%, 98%, 96%, and 91% for veins treated with the VenaSealTM system (p <0.01). Conclusions: The VenaSealTM system had significantly better occlusion rates than the VariClose® system.

• Klíčová slova
• VenaSealTM, VariClose,
• MeSH
• Kaplanův-Meierův odhad MeSH
• kyanoakryláty * aplikace a dávkování   farmakologie   terapeutické užití   MeSH
• lidé MeSH
• retrospektivní studie MeSH
• varixy terapie   MeSH
• vena saphena chirurgie   patologie   MeSH
• vény patologie   MeSH
• výsledek terapie MeSH
• zařízení na uzavírání cév MeSH
• žilní insuficience terapie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• práce podpořená grantem MeSH

OBJECTIVES: The aim of this study was to assess occlusion rates of saphenous veins treated with the VariClose vein sealing system. METHODS: A retrospective analysis including a total of 64 patients from four centres from the Czech Republic. Occlusion was defined as a non-compressible vein with absence of flow with exception to the first 3 cm from the saphenofemoral or saphenopopliteal junction on duplex ultrasound. RESULTS: In 64 patients a total of 79 veins were treated. Technical success of the procedure was achieved in 74 (94%) of cases. The mean follow-up was 5.5 months. The closure rates calculated by the Kaplan-Meier method at 1, 3, 6 and 12 months were 94%, 85%, 69% and 36%, respectively, and there were no significant differences between centers. The average difference in VCSS score before and after the procedure was 1.8. CONCLUSIONS: The present study demonstrated surprisingly worse occlusion rates than the current literature.

• MeSH
• lidé MeSH
• retrospektivní studie MeSH
• varixy * diagnostické zobrazování   chirurgie   MeSH
• vena saphena diagnostické zobrazování   chirurgie   MeSH
• výsledek terapie MeSH
• žilní insuficience * diagnostické zobrazování   terapie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

BACKGROUND: One of the three commercially available cyanoacrylate venous glues used for the treatment of saphenous vein insufficiency is the VariClose® vein sealing system. Previous studies have documented a high rate of occlusion and minimal postoperative complications. The aim of this study was to compare occlusion rates and clinical outcomes of endovenous laser treatment with the VariClose® vein sealing system in the treatment of truncal vein insufficiency. PATIENTS AND METHODS: Retrospective non-randomized single center study with prospectively collected data comparing endovenous laser treatment and VariClose® procedures between April 2018 and November 2019. RESULTS: VariClose® was used in 27 patients (30 veins) and endovenous laser treatment in 42 patients (51 veins). The occlusion rate at one, three, and six months were 96%, 85%, and 65% for VariClose® procedures and 100%, 100%, and 97% for endovenous laser treatment procedures (p = 0.01), respectively. Reduction of VCSS scores before treatment and at the last postoperative follow-up visit in the VariClose® group dropped by an average of 1.8 ± 1.6 and in the endovenous laser treatment by an average of 3.3 ± 2.9 (p = 0.01). CONCLUSION: VariClose® vein sealing system is inferior to endovenous laser treatment as a treatment option for varicose veins as it has a higher recanalization rate.

• MeSH
• laserová terapie * škodlivé účinky   metody   MeSH
• lidé MeSH
• retrospektivní studie MeSH
• varixy * diagnostické zobrazování   chirurgie   MeSH
• vena saphena diagnostické zobrazování   chirurgie   MeSH
• výsledek terapie MeSH
• žilní insuficience * diagnostické zobrazování   chirurgie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH