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MeSH: bacilární dyzentérie-mikrobiologie

26 záznamů v Články Filtry

Článek

Shigelóza u osob s HIV

Jilich, David, 1979-
Autor Autorita Univerzita Karlova, 1. lékařská fakulta a Fakultní nemocnice Bulovka, Klinika infekčních, parazitárních a tropických nemocí

Česká dermatovenerologie. 2021 ; 11 (2) : 53-54.

ISSN 1805-0611
Medvik
Zdroj

MeSH
antibakteriální látky terapeutické užití MeSH
bacilární dyzentérie * diagnóza farmakoterapie mikrobiologie MeSH
dospělí MeSH
HIV infekce MeSH
homosexualita mužská MeSH
lidé MeSH
rizikové faktory MeSH
rizikový sex MeSH
Shigella izolace a purifikace patogenita MeSH
Check Tag
dospělí MeSH
lidé MeSH
mužské pohlaví MeSH
Publikační typ
kazuistiky MeSH

Článek

Shigella flexneri: an emerging pathogen

Folia microbiologica. 2020 ; 65 (2) : 275-291. [pub] 20200205

Folia microbiol. (Prague)
ISSN 1874-9356
Medvik
Zdroj

Shigella flexneri is a leading etiologic agent of diarrhea in low socioeconomic countries. Notably, various serotypes in S. flexneri are reported from different regions of the world. The precise approximations of illness and death owing to shigellosis are missing in low socioeconomic countries, although it is widespread in different regions. The inadequate statistics available reveal S. flexneri to be a significant food and waterborne pathogen. All over the world, different antibiotic-resistant strains of S. flexneri serotypes have been emerged especially multidrug-resistant strains. Recently, increased resistance was observed in cephalosporins (3rd generation), azithromycin, and fluoroquinolones. There is a need for a continuous surveillance study on antibiotic resistance that will be helpful in the update of the antibiogram. The shigellosis burden can be reduced by adopting preventive measures like delivery of safe drinking water, suitable sanitation, and development of an effective and inexpensive multivalent vaccine. This review attempts to provide the recent findings of S. flexneri related to epidemiology and the emergence of multidrug resistance.

MeSH
antibakteriální látky farmakologie MeSH
bacilární dyzentérie farmakoterapie mikrobiologie MeSH
bakteriální léková rezistence MeSH
lidé MeSH
objevující se infekční nemoci farmakoterapie mikrobiologie MeSH
Shigella flexneri účinky léků genetika izolace a purifikace fyziologie MeSH
zvířata MeSH
Check Tag
lidé MeSH
zvířata MeSH
Publikační typ
časopisecké články MeSH
přehledy MeSH

Článek

Evaluation of antimicrobial resistance among Salmonella and Shigella isolates in the University Hospital "St. George," Plovdiv, Bulgaria

Folia microbiologica. 2017 ; 62 (2) : 117-125. [pub] 20161019

Folia microbiol. (Prague)
ISSN 1874-9356
Medvik
Zdroj

The aim of this work is to study the epidemiology and antimicrobial resistance to the most commonly used antibiotics for the treatment of acute gastroenteritis caused by Salmonella and Shigella at the largest Bulgarian hospital-University Hospital "St. George," Plovdiv-for the period 2009-2013. Two hundred ninety strains were in vitro tested for resistance to 15 antimicrobial agents. The presence of extended-spectrum beta-lactamases (ESBLs) was demonstrated by a variety of specialized tests. For comparison, a collection of 28 strains submitted by the National Reference Laboratory (NRL) "Enteric Infections" at the National Center of Infectious and Parasitic Diseases (NCIPD), Sofia, was also tested for the production of ESBLs. In isolates, phenotypically demonstrated as ESBL producers, polymerase chain reaction (PCR) detection of the genes bla-CTX-M, bla-SHV, and bla-TEM was performed. Among the 290 tested isolates, only two- Salmonella serotype Livingstone and Shigella flexneri-were phenotypically proven to be ESBL producers. Only 4 strains from the collection of 28, submitted from the NRL "Intestinal Infections" in NCIPD, Sofia, were phenotypically confirmed as ESBL producers. The presence of the bla-CTX-M gene was detected in all of the tested strains (4 from NRL, NCIPD, Sofia, and 2 from the University Hospital St. George, Plovdiv), the bla-SHV gene only in strain S. Livingstone from Plovdiv, and the bla-TEM gene in two from Sofia and one (again S. Livingstone) from Plovdiv. In conclusion, Salmonella and Shigella isolates from patients hospitalized at the University Hospital St. George, Plovdiv, with acute gastroenteritis demonstrate good susceptibility to the most commonly used antibiotic agents, including azithromycin.

MeSH
akutní nemoc MeSH
antibakteriální látky farmakologie MeSH
bacilární dyzentérie diagnóza farmakoterapie epidemiologie mikrobiologie MeSH
bakteriální léková rezistence genetika MeSH
beta-laktamasy genetika metabolismus MeSH
dítě MeSH
DNA bakterií genetika MeSH
dospělí MeSH
exprese genu MeSH
gastroenteritida diagnóza farmakoterapie epidemiologie mikrobiologie MeSH
kojenec MeSH
lidé středního věku MeSH
lidé MeSH
mikrobiální testy citlivosti MeSH
mladiství MeSH
nemocnice univerzitní MeSH
novorozenec MeSH
předškolní dítě MeSH
retrospektivní studie MeSH
Salmonella účinky léků enzymologie genetika růst a vývoj MeSH
salmonelóza diagnóza farmakoterapie epidemiologie mikrobiologie MeSH
Shigella účinky léků enzymologie genetika MeSH
Check Tag
dítě MeSH
dospělí MeSH
kojenec MeSH
lidé středního věku MeSH
lidé MeSH
mladiství MeSH
mužské pohlaví MeSH
novorozenec MeSH
předškolní dítě MeSH
ženské pohlaví MeSH
Publikační typ
časopisecké články MeSH
Geografické názvy
Bulharsko epidemiologie MeSH

Článek

Global phylogeography and evolutionary history of Shigella dysenteriae type 1

Nature microbiology. 2016 ; 1 (-) : 16027. [pub] 20160321

Nat Microbiol
ISSN 2058-5276
Medvik
Zdroj

Together with plague, smallpox and typhus, epidemics of dysentery have been a major scourge of human populations for centuries(1). A previous genomic study concluded that Shigella dysenteriae type 1 (Sd1), the epidemic dysentery bacillus, emerged and spread worldwide after the First World War, with no clear pattern of transmission(2). This is not consistent with the massive cyclic dysentery epidemics reported in Europe during the eighteenth and nineteenth centuries(1,3,4) and the first isolation of Sd1 in Japan in 1897(5). Here, we report a whole-genome analysis of 331 Sd1 isolates from around the world, collected between 1915 and 2011, providing us with unprecedented insight into the historical spread of this pathogen. We show here that Sd1 has existed since at least the eighteenth century and that it swept the globe at the end of the nineteenth century, diversifying into distinct lineages associated with the First World War, Second World War and various conflicts or natural disasters across Africa, Asia and Central America. We also provide a unique historical perspective on the evolution of antibiotic resistance over a 100-year period, beginning decades before the antibiotic era, and identify a prevalent multiple antibiotic-resistant lineage in South Asia that was transmitted in several waves to Africa, where it caused severe outbreaks of disease.