• MeSH
• absces diagnostické zobrazování   MeSH
• děložní krvácení diagnostické zobrazování   MeSH
• gynekologická onemocnění diagnostické zobrazování   MeSH
• gynekologie MeSH
• koronavirové infekce prevence a kontrola   přenos   MeSH
• lidé MeSH
• nádory ženských pohlavních orgánů diagnostické zobrazování   MeSH
• nemoci ovaria diagnostické zobrazování   MeSH
• ovariální cysty diagnostické zobrazování   MeSH
• ovariální hyperstimulační syndrom diagnostické zobrazování   MeSH
• pandemie prevence a kontrola   MeSH
• pánevní zánět diagnostické zobrazování   MeSH
• poskytování zdravotní péče metody   organizace a řízení   MeSH
• přenos infekce z pacienta na zdravotnického pracovníka prevence a kontrola   MeSH
• přenos infekce ze zdravotnického pracovníka na pacienta prevence a kontrola   MeSH
• spontánní ruptura diagnostické zobrazování   MeSH
• torzní deformity diagnostické zobrazování   MeSH
• třídění pacientů metody   MeSH
• ultrasonografie metody   MeSH
• virová pneumonie prevence a kontrola   přenos   MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• konsensus - konference MeSH

• MeSH
• Betacoronavirus izolace a purifikace   MeSH
• COVID-19 MeSH
• karanténa MeSH
• koronavirové infekce diagnóza   mortalita   prevence a kontrola   MeSH
• lidé MeSH
• masky MeSH
• ochrana veřejného zdraví metody   MeSH
• ochranné faktory MeSH
• pandemie prevence a kontrola   MeSH
• SARS-CoV-2 MeSH
• virová pneumonie diagnóza   mortalita   prevence a kontrola   MeSH
• zdravotní politika * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH
• Evropa MeSH

The global SARS-CoV-2 pandemic dictates that anti-contagion strategies should become matters of essential routine in everyday life. Fomite transference is one of the routes of transmission that has been considered for this virus. However, the risks associated with contaminated surfaces of food packaging kept in refrigerators have not yet been adequately assessed. In this study, a surrogate virus, Alphacoronavirus 1, was used to investigate the persistence of coronavirus dried on a plastic carrier at 4 °C. Techniques of wet wiping, with or without disinfectant saturation, were employed to evaluate their effectiveness in the elimination of the virus. If not wiped, the loss of infectivity of the virus on plastic surfaces was, on average, 0.93 log10 (i.e. 83%) per day of storage at 4 °C. Wiping with water-saturated material reduced the initial virus titre on the plastic carrier by 2.4 log10 (99.6%); the same results were achieved through wiping with bactericidal wipes containing ethanol. Wipes saturated with a combination of disinfectant agents (didecyl-dimethyl-ammonium chloride, hydrogen peroxide) decreased the virus titre still more efficiently, by 3.8 log10 (99.98%) and also significantly prevented further transfer of the virus to a secondary surface through wiping. Thus SARS-CoV-2 transmission potential via contaminated plastic packaging and food may be efficiently eliminated by wet-wiping, especially when wipes saturated with specific disinfectants are used.

• MeSH
• antibakteriální látky MeSH
• Betacoronavirus MeSH
• bezpečnost potravin * MeSH
• chlazení * MeSH
• Coronavirus MeSH
• COVID-19 MeSH
• dezinfekce metody   MeSH
• dezinficiencia MeSH
• ethanol MeSH
• fomity virologie   MeSH
• koronavirové infekce epidemiologie   prevence a kontrola   virologie   MeSH
• kvartérní amoniové sloučeniny MeSH
• lidé MeSH
• obaly potravin * MeSH
• pandemie prevence a kontrola   MeSH
• peroxid vodíku MeSH
• plastické hmoty * MeSH
• SARS-CoV-2 MeSH
• skladování potravin metody   MeSH
• virová pneumonie epidemiologie   prevence a kontrola   virologie   MeSH
• voda MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH

Childhood, adolescent, and young adult (CAYA) cancer survivors may be at risk for a severe course of COVID-19. Little is known about the clinical course of COVID-19 in CAYA cancer survivors, or if additional preventive measures are warranted. We established a working group within the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) to summarize existing evidence and worldwide recommendations regarding evidence about factors/conditions associated with risk for a severe course of COVID-19 in CAYA cancer survivors, and to develop a consensus statement to provide guidance for healthcare practitioners and CAYA cancer survivors regarding COVID-19.

• MeSH
• Betacoronavirus * MeSH
• COVID-19 MeSH
• dítě MeSH
• dospělí MeSH
• koronavirové infekce epidemiologie   prevence a kontrola   terapie   přenos   MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• nádory epidemiologie   terapie   MeSH
• pandemie prevence a kontrola   MeSH
• předškolní dítě MeSH
• přežívající onkologičtí pacienti * MeSH
• SARS-CoV-2 MeSH
• směrnice pro lékařskou praxi jako téma MeSH
• virová pneumonie epidemiologie   prevence a kontrola   terapie   přenos   MeSH
• Check Tag
• dítě MeSH
• dospělí MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• předškolní dítě MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• multicentrická studie MeSH

AIMS: A reduction of habitual physical activity due to prolonged COVID-19 quarantine can have serious consequences for patients with cardiovascular diseases, such as heart failure. This study aimed to explore the effect of COVID-19 nationwide quarantine on accelerometer-assessed physical activity of heart failure patients. METHODS AND RESULTS: We analysed the daily number of steps in 26 heart failure patients during a 6-week period that included 3 weeks immediately preceding the onset of the quarantine and the first 3 weeks of the quarantine. The daily number of steps was assessed using a wrist-worn accelerometer worn by the patients as part of an ongoing randomized controlled trial. Multilevel modelling was used to explore the effect of the quarantine on the daily step count adjusted for weather conditions. As compared with the 3 weeks before the onset of the quarantine, the step count was significantly lower during each of the first 3 weeks of the quarantine (P < 0.05). When the daily step count was averaged across the 3 weeks before and during the quarantine, the decrease amounted to 1134 (SE 189) steps per day (P < 0.001), which translated to a 16.2% decrease. CONCLUSIONS: The introduction of the nationwide quarantine due to COVID-19 had a detrimental effect on the level of habitual physical activity in heart failure patients, leading to an abrupt decrease of daily step count that lasted for at least the 3-week study period. Staying active and maintaining sufficient levels of physical activity during the COVID-19 pandemic are essential despite the unfavourable circumstances of quarantine.

• MeSH
• akcelerometrie metody   MeSH
• časové faktory MeSH
• COVID-19 MeSH
• cvičení fyziologie   MeSH
• dospělí MeSH
• hodnocení rizik MeSH
• karanténa * MeSH
• kohortové studie MeSH
• koronavirové infekce epidemiologie   prevence a kontrola   MeSH
• lidé středního věku MeSH
• lidé MeSH
• pandemie prevence a kontrola   statistika a číselné údaje   MeSH
• prognóza MeSH
• retrospektivní studie MeSH
• senioři MeSH
• srdeční selhání patofyziologie   rehabilitace   MeSH
• tělesná výkonnost fyziologie   MeSH
• test chůzí statistika a číselné údaje   MeSH
• virová pneumonie epidemiologie   prevence a kontrola   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• multicentrická studie MeSH
• práce podpořená grantem MeSH

Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has spread worldwide triggering a pandemic during the year 2020. The proportion of persons infected with SARS-CoV-2 whose infection remained subclinical is not known. However, such information is important to determine whether the control measures currently employed are sufficient to halt the spread of the virus. Current study has examined the seroprevalence of anti-SARS-CoV-2 antibodies in a population of 92 healthcare professionals working with patients with inflammatory bowel disease (IBD). The enzyme-linked immunosorbent assay (ELISA) test system for SARS-CoV-2 IgG from EUROIMMUN Medizinische Labordiagnostika AG (Germany) was used. Very low herd antibody-mediated immunity was proven, less than 2%, although we have been faced with the COVID-19 pandemic for several months. Anti-SARS-CoV-2 IgG antibody testing is currently unable to provide sufficient information about our anti-infectious immunity.

• MeSH
• ambulantní zařízení organizace a řízení   MeSH
• ELISA MeSH
• epidemický výskyt choroby prevence a kontrola   MeSH
• hodnocení rizik MeSH
• hygiena práce * MeSH
• idiopatické střevní záněty epidemiologie   imunologie   terapie   MeSH
• imunoglobulin G analýza   imunologie   MeSH
• klinické laboratorní techniky metody   statistika a číselné údaje   MeSH
• kolektivní imunita MeSH
• koronavirové infekce diagnóza   epidemiologie   prevence a kontrola   MeSH
• lidé MeSH
• odhad potřeb MeSH
• pandemie prevence a kontrola   statistika a číselné údaje   MeSH
• přenos infekce z pacienta na zdravotnického pracovníka prevence a kontrola   MeSH
• protilátky virové imunologie   MeSH
• séroepidemiologické studie MeSH
• virová pneumonie epidemiologie   prevence a kontrola   MeSH
• zdravotnický personál MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Německo MeSH

The mandatory face mask wearing was implemented in the Czech Republic and Slovakia shortly after the COVID-19 outbreak in Central Europe. So far, the number of COVID-19-associated deaths per 100,000 individuals is far lower in these countries as compared with other neighbouring or close countries. The use of face masks in public may not protect the general public from contracting the virus, however, presumptively decreases the viral load and contributes to a favourable clinical outcome in COVID-19 disease. A certain time is required for antigen-specific T cells and B cells to fully develop. Obligatory face mask wearing in public favours the virus transmission through oral mucosa and/or conjunctival epithelium, which enables the adaptive immune responses to evolve. In the case of inhalation of high loads of SARS-CoV-2, the time for the development of fully protective adaptive immune responses seems to be insufficient. Then, a less specific and more damaging innate immune response prevails.

• MeSH
• Betacoronavirus MeSH
• koronavirové infekce epidemiologie   prevence a kontrola   přenos   MeSH
• lidé MeSH
• masky * MeSH
• ochranné oděvy MeSH
• osobní ochranné prostředky MeSH
• pandemie prevence a kontrola   MeSH
• virová nálož MeSH
• virová pneumonie epidemiologie   prevence a kontrola   přenos   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH
• Slovenská republika MeSH

BACKGROUND: The following position statement from the Union of the European Phoniatricians, updated on 25th May 2020 (superseding the previous statement issued on 21st April 2020), contains a series of recommendations for phoniatricians and ENT surgeons who provide and/or run voice, swallowing, speech and language, or paediatric audiology services. OBJECTIVES: This material specifically aims to inform clinical practices in countries where clinics and operating theatres are reopening for elective work. It endeavours to present a current European view in relation to common procedures, many of which fall under the aegis of aerosol generating procedures. CONCLUSION: As evidence continues to build, some of the recommended practices will undoubtedly evolve, but it is hoped that the updated position statement will offer clinicians precepts on safe clinical practice.

• MeSH
• audiologie metody   normy   MeSH
• Betacoronavirus izolace a purifikace   MeSH
• COVID-19 MeSH
• dítě MeSH
• koronavirové infekce epidemiologie   prevence a kontrola   virologie   MeSH
• lidé MeSH
• osobní ochranné prostředky normy   zásobování a distribuce   MeSH
• otorinolaryngologie metody   normy   MeSH
• pandemie prevence a kontrola   MeSH
• pediatrie normy   MeSH
• poruchy hlasu diagnóza   chirurgie   virologie   MeSH
• poruchy polykání diagnóza   chirurgie   virologie   MeSH
• povinné vyšetření normy   MeSH
• předškolní dítě MeSH
• SARS-CoV-2 MeSH
• směrnice pro lékařskou praxi jako téma MeSH
• společnosti lékařské organizace a řízení   MeSH
• virová pneumonie epidemiologie   prevence a kontrola   virologie   MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• předškolní dítě MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Evropa MeSH

BACKGROUND AND AIMS: Although coronavirus disease 2019 (COVID-19) has affected endoscopy services globally, the impact on trainees has not been evaluated. We aimed to assess the impact of COVID-19 on procedural volumes and on the emotional well-being of endoscopy trainees worldwide. METHODS: An international survey was disseminated over a 3-week period in April 2020. The primary outcome was the percentage reduction in monthly procedure volume before and during COVID-19. Secondary outcomes included potential variation of COVID-19 impact between different continents and rates and predictors of anxiety and burnout among trainees. RESULTS: Across 770 trainees from 63 countries, 93.8% reported a reduction in endoscopy case volume. The median percentage reduction in total procedures was 99% (interquartile range, 85%-100%), which varied internationally (P < .001) and was greatest for colonoscopy procedures. Restrictions in case volume and trainee activity were common barriers. A total of 71.9% were concerned that the COVID-19 pandemic could prolonged training. Anxiety was reported in 52.4% of respondents and burnout in 18.8%. Anxiety was independently associated with female gender (odds ratio [OR], 2.15; P < .001), adequacy of personal protective equipment (OR, 1.75; P = .005), lack of institutional support for emotional health (OR, 1.67; P = .008), and concerns regarding prolongation of training (OR, 1.60; P = .013). Modifying existing national guidelines to support adequate endoscopy training during the pandemic was supported by 68.9%. CONCLUSIONS: The COVID-19 pandemic has led to restrictions in endoscopic volumes and endoscopy training, with high rates of anxiety and burnout among endoscopy trainees worldwide. Targeted measures by training programs to address these key issues are warranted to improve trainee well-being and support trainee education.

• MeSH
• Betacoronavirus * MeSH
• COVID-19 MeSH
• dospělí MeSH
• endoskopie výchova   statistika a číselné údaje   MeSH
• internacionalita * MeSH
• koronavirové infekce epidemiologie   prevence a kontrola   přenos   MeSH
• lidé MeSH
• pandemie prevence a kontrola   MeSH
• profesionální vyhoření epidemiologie   MeSH
• průzkumy a dotazníky MeSH
• SARS-CoV-2 MeSH
• úzkost epidemiologie   MeSH
• virová pneumonie epidemiologie   prevence a kontrola   přenos   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

While the world is facing an unprecedented pandemic with COVID-19, patients with chronic diseases need special attention and if warranted adaptation of their regular treatment plan. In children, allergy and asthma are among the most prevalent non-communicable chronic diseases, and healthcare providers taking care of these patients need guidance. At the current stage of knowledge, children have less severe symptoms of COVID-19, and severe asthma and immunodeficiency are classified as risk factors. In addition, there is no evidence that currently available asthma and allergy treatments, including antihistamines, corticosteroids, and bronchodilators, increase the risk of severe disease from COVID-19. Most countries affected by COVID-19 have opted for nationwide confinement, which means that communication with the primary clinician is often performed by telemedicine. Optimal disease control of allergic, asthmatic, and immunodeficient children should be sought according to usual treatment guidelines. This statement of the EAACI Section on Pediatrics puts forward six recommendations for the management of childhood allergies and immunodeficiencies based on six underlying facts and existing evidence.

• MeSH
• akademie a ústavy MeSH
• alergie terapie   MeSH
• Betacoronavirus * MeSH
• COVID-19 MeSH
• dítě MeSH
• kojenec MeSH
• koronavirové infekce prevence a kontrola   MeSH
• lidé MeSH
• mladiství MeSH
• pandemie prevence a kontrola   MeSH
• pediatrie metody   MeSH
• předškolní dítě MeSH
• SARS-CoV-2 MeSH
• směrnice pro lékařskou praxi jako téma MeSH
• syndromy imunologické nedostatečnosti terapie   MeSH
• virová pneumonie prevence a kontrola   MeSH
• Check Tag
• dítě MeSH
• kojenec MeSH
• lidé MeSH
• mladiství MeSH
• předškolní dítě MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Geografické názvy
• Evropa MeSH