-
Something wrong with this record ?
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
I. de Rojas, S. Moreno-Grau, N. Tesi, B. Grenier-Boley, V. Andrade, IE. Jansen, NL. Pedersen, N. Stringa, A. Zettergren, I. Hernández, L. Montrreal, C. Antúnez, A. Antonell, RM. Tankard, JC. Bis, R. Sims, C. Bellenguez, I. Quintela, A....
Language English Country Great Britain
Document type Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Validation Study
Persistent link
https://www.medvik.cz/link/bmc21018465
Grant support
U24 AG021886
NIA NIH HHS - United States
U01 AG032984
NIA NIH HHS - United States
U01 AG016976
NIA NIH HHS - United States
N01AG12100
NIA NIH HHS - United States
U01 AG058589
NIA NIH HHS - United States
082604/2/07/Z
Wellcome Trust - United Kingdom
Wellcome Trust - United Kingdom
U01 AG049505
NIA NIH HHS - United States
R01 HL105756
NHLBI NIH HHS - United States
503480
Medical Research Council - United Kingdom
Online
Full text
NLK
Directory of Open Access Journals
from 2015
Free Medical Journals
from 2010
Nature Open Access
from 2010-12-01
PubMed Central
from 2012
Europe PubMed Central
from 2012
ProQuest Central
from 2010-01-01
Open Access Digital Library
from 2015-01-01
Open Access Digital Library
from 2015-01-01
Medline Complete (EBSCOhost)
from 2012-11-01
Health & Medicine (ProQuest)
from 2010-01-01
ROAD: Directory of Open Access Scholarly Resources
from 2010
Springer Nature OA/Free Journals
from 2010-12-01
- MeSH
- Alzheimer Disease epidemiology genetics pathology MeSH
- Amyloid beta-Protein Precursor genetics metabolism MeSH
- Apolipoproteins E genetics MeSH
- Genome-Wide Association Study MeSH
- Datasets as Topic MeSH
- Genetic Predisposition to Disease MeSH
- Heterozygote MeSH
- Risk Assessment methods MeSH
- Polymorphism, Single Nucleotide MeSH
- Cohort Studies MeSH
- Middle Aged MeSH
- Humans MeSH
- Multifactorial Inheritance * MeSH
- Follow-Up Studies MeSH
- Risk Factors MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Case-Control Studies MeSH
- Age of Onset MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Research Support, N.I.H., Extramural MeSH
- Validation Study MeSH
Genetic discoveries of Alzheimer's disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer's disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer's disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer's disease.
1st Department of Neurology Aristotle University of Thessaloniki Thessaloniki Greece
A 1 Virtanen Institute for Molecular Sciences University of Eastern Finland Kuopio Finland
Alzheimer Research Center and Memory Clinic Andalusian Institute for Neuroscience Málaga Spain
APHP Hôpital Broca Paris France
APHP Hôpital Brousse equipe INSERM 1178 MOODS Villejuif France
Athens Association of Alzheimer's disease and Related Disorders Athens Greece
Azienda Ospedaliero Universitaria Careggi Largo Brambilla Florence Italy
Azienda Ospedaliero Universitaria Parma Italy
Bristol Medical School University of Bristol Southmead Hospital Bristol UK
CAEBI Centro Andaluz de Estudios Bioinformáticos Sevilla Spain
Campus for Ageing anf Vitality Newcastle upon Tyne UK
Cardiovascular Health Research Unit Department of Medicine University of Washington Seattle WA USA
Center for Neurosciences Vrije Universiteit Brussel Brussels Belgium
Centre of Age Related Medicine Stavanger University Hospital Stavanger Norway
Centro de Biología Molecular Severo Ochoa Madrid Spain
CHU de Bordeaux Pole de Santé Publique Bordeaux France
CIEN Foundation Queen Sofia Foundation Alzheimer Center Madrid Spain
Cleveland Institute for Computational Biology Case Western Reserve University Cleveland OH USA
Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden
Delft Bioinformatics Lab Delft Univeristy of Technology Delft The Netherlands
Departamento de Medicina Universidad de Oviedo Oviedo Spain
Department of Biomedical Sciences University of Antwerp Antwerp Belgium
Department of Biostatistics Boston University School of Public Health Boston MA USA
Department of Clinical Biochemistry Herlev Gentofte Hospital Herlev Denmark
Department of Clinical Biochemistry Rigshospitalet Copenhagen Denmark
Department of Clinical Sciences and Community Health University of Milan Milan Italy
Department of Epidemiology Erasmus Medical Center Rotterdam The Netherlands
Department of Geriatric Medicine Oslo University Hospital Oslo Norway
Department of Geriatric Psychiatry University Hospital of Psychiatry Zürich Zürich Switzerland
Department of Laboratory Diagnostics 3 Laboratory of Analysis Brescia Hospital Brescia Italy
Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden
Department of Medical Genetics Oslo University Hospital Oslo Norway
Department of Neurodegenerative Disease UCL Institute of Neurology London UK
Department of Neurology Boston University School of Medicine Boston MA USA
Department of Neurology CIEN Foundation Queen Sofia Foundation Alzheimer Center Madrid Spain
Department of Neurology Columbia University New York NY USA
Department of Neurology Hospital Universitario Donostia San Sebastian Spain
Department of Neurology La Paz University Hospital Madrid Spain
Department of Neurology Medical School University of Cyprus Nicosia Cyprus
Department of Neurology University of Bonn Bonn Germany
Department of Neurology VUB University Hospital Brussels Brussels Belgium
Department of Neuroscience Rita Levi Montalcini University of Torino Torino Italy
Department of Nutrition and Dietetics Harokopio University Athens Greece
Department of Population Health Sciences UT Health San Antonio San Antonio TX USA
Department of Primary Medical Care University Medical Centre Hamburg Eppendorf Hamburg Germany
Department of Psychiatry and Psychotherapy University Medical Center Goettingen Goettingen Germany
Department of Psychiatry and Psychotherapy University of Cologne Medical Faculty Cologne Germany
Department of Psychiatry Social Medicine Center East Donauspital Vienna Austria
Department of Psychology University of California Riverside Riverside CA USA
Department of Public Health and Caring Sciences Geriatrics Uppsala Sweden
Department of Sociology VU University Amsterdam The Netherlands
Division of Clinical Neurosciences School of Medicine University of Southampton Southampton UK
Division of Mental Health and Addiction Oslo University Hospital Oslo Norway
EA 4468 Sorbonne Paris Cité Université Paris Descartes Paris France
Faculty of Medicine University of Lisbon Lisbon Portugal
Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan Italy
Fondazione IRCCS Istituto Neurologico Carlo Besta Milan Italy
Framingham Heart Study Framingham MA USA
Fundació Docència i Recerca MútuaTerrassa Terrassa Barcelona Spain
Fundación Pública Galega de Medicina Xenómica CIBERER IDIS Santiago de Compostela Spain
Geriatic Unit Fondazione Cà Granda IRCCS Ospedale Maggiore Policlinico Milan Italy
German Center for Neurodegenerative Diseases Berlin Germany
German Center for Neurodegenerative Diseases Bonn Germany
German Center for Neurodegenerative Diseases Goettingen Germany
German Center for Neurodegenerative Diseases Magdeburg Germany
German Center for Neurodegenerative Diseases Munich Germany
Gertrude H Sergievsky Center Columbia University New York NY USA
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases San Antonio TX USA
Haugesund Hospital Helse Fonna Department of Research and Innovation Haugesund Norway
Hospital de Cabueñes Gijón Spain
Hospital La Paz Institute for Health Research IdiPAZ Madrid Spain
Hospital Universitario Ramon y Cajal IRYCIS Madrid Spain
Human Genome Sequencing Center Baylor College of Medicine Houston TX USA
Inserm U1172 CHU DISTAlz LiCEND Univ Lille Lille France
Insititute for Regenerative Medicine University of Zürich Zürich Switzerland
Institut de Recerca Biomedica de Lleida Lleida Spain
Institute Born Bunge University of Antwerp Antwerp Belgium
Institute of Biomedicine University of Eastern Finland Kuopio Finland
Institute of Clinical Medicine Internal Medicine University of Eastern Finland Kuopio Finland
Institute of Clinical Medicine Neurology University of Eastern Finland Kuopio Finland
Institute of Clinical Medicine University of Oslo Oslo Norway
Institute of Gerontology and Geriatrics Department of Medicine University of Perugia Perugia Italy
Institute of Medical Biometry Informatics and Epidemiology University Hospital of Bonn Bonn Germany
Institute of Medical Genetics and Pathology University Hospital Basel Basel Switzerland
Institute of Neurology Catholic University of the Sacred Heart School of Medicine Milan Italy
Institute of Public Health and Clinical Nutrition University of Eastern Finland Kuopio Finland
Instituto de Investigacion Sanitaria 'Hospital la Paz' Madrid Spain
Instituto de Investigación Sanitaria del Principado de Asturias Oviedo Spain
Instituto de Investigación Sanitaria Hospital Clínico San Carlos Madrid Spain
International Clinical Research Center St Anne's University Hospital Brno Brno Czech Republic
IRCCS Fondazione Don Carlo Gnocchi Florence Italy
Laboratorio de Genética Hospital Universitario Central de Asturias Oviedo Spain
Laboratory for Cognitive Neurology Department of Neurosciences University of Leuven Leuven Belgium
Laboratory of Neurogenetics Institute Born Bunge Antwerp Belgium
Laboratory of Neuropsychiatry IRCCS Santa Lucia Foundation Rome Italy
MAC Memory Clinic IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli Brescia Italy
Mathematics and Statistics Murdoch University Perth WA Australia
MRC Prion Unit at UCL Institute of Prion Diseases London UK
Munich Cluster for Systems Neurology Munich Germany
Neurocenter neurology Kuopio University Hospital Kuopio Finland
Neuroepidemiology and Ageing Research Unit School of Public Health Imperial College London London UK
Neurology Department University Hospitals Leuven Leuven Belgium
Neurology Service Marqués de Valdecilla University Hospital Santander Spain
Neurology Unit 'San Gerardo' hospital Monza Italy
Neuroscience Center Zurich University of Zurich and ETH Zurich Zurich Switzerland
Neuroscience Research Australia Sydney NSW Australia
Neurosciences Area Instituto Biodonostia San Sebastian Spain
NORMENT Centre Institute of Clinical Medicine University of Oslo Oslo Norway
NORMENT Department of Clinical Science University of Bergen Bergen Norway
Norwegian National Advisory Unit on Ageing and Health Vestfold Hospital Trust Tønsberg Norway
Nuffield Department of Clinical Neurosciences Oxford UK
Nuffield Department of Population Health University of Oxford Oxford UK
Old age Psychiatry University Hospital of Lausanne Lausanne Switzerland
Population Health Unit Finnish Institute for Health and Welfare Helsinki Finland
Reference Center for Biological Markers of Dementia University of Antwerp Antwerp Belgium
School of Medicine University of Thessaly Larissa Greece
Schools of Life Sciences and Medicine University of Nottingham Nottingham UK
Servei de Neurologia Hospital Universitari i Politècnic La Fe Valencia Spain
Servicio de Neurología Hospital Universitario Central de Asturias Oviedo Spain
Servicio de Neurología Hospital Universitario de Gran Canaria Dr Negrín Las Palmas Spain
Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders Madrid Spain
Stockholms Sjukhem Research and Development Unit Stockholm Sweden
Translational and Clincial Research Institute Newcastle University Newcastle upon Tyne UK
Translational Neuroscience Laboratory McLean Hospital Harvard Medical School Belmont MA USA
UFIEC Instituto de Salud Carlos 3 Madrid Spain
UK Dementia Research Institute at Cardiff Cardiff University Cardiff UK
UK Dementia Research Institute at UCL London UK
UKDRI Cardiff Cardiff University Cardiff UK
Unidad de Demencias Hospital Clínico Universitario Virgen de la Arrixaca Murcia Spain
Unidad Mixta de Neurologia Genètica Instituto de Investigación Sanitaria La Fe Valencia Spain
Unit for Hereditary Dementias Theme Aging Karolinska University Hospital Solna Stockholm Sweden
Unit of Clinical Pharmacology University Hospital of Cagliari Cagliari Italy
Unit of Neuroscience DIMEC University of Parma Parma Italy
Unitat de Genètica Molecular Institut de Biomedicina de València CSIC Valencia Spain
Unitat Trastorns Cognitius Hospital Universitari Santa Maria de Lleida Lleida Spain
Universidad Autónoma de Madrid Madrid Spain
Université Paris Saclay UVSQ Inserm CESP Team MOODS Le Kremlin Bicêtre Paris France
University of Bergen Institute of Clinical Medicine Bergen Norway
University of Milan Dino Ferrari Center Milan Italy
University of Zürich Zürich Switzerland
VIB Center for Molecular Neurology Antwerp Belgium
Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21018465
- 003
- CZ-PrNML
- 005
- 20210830100041.0
- 007
- ta
- 008
- 210728s2021 xxk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1038/s41467-021-22491-8 $2 doi
- 035 __
- $a (PubMed)34099642
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxk
- 100 1_
- $a de Rojas, Itziar $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 245 10
- $a Common variants in Alzheimer's disease and risk stratification by polygenic risk scores / $c I. de Rojas, S. Moreno-Grau, N. Tesi, B. Grenier-Boley, V. Andrade, IE. Jansen, NL. Pedersen, N. Stringa, A. Zettergren, I. Hernández, L. Montrreal, C. Antúnez, A. Antonell, RM. Tankard, JC. Bis, R. Sims, C. Bellenguez, I. Quintela, A. González-Perez, M. Calero, E. Franco-Macías, J. Macías, R. Blesa, L. Cervera-Carles, M. Menéndez-González, A. Frank-García, JL. Royo, F. Moreno, R. Huerto Vilas, M. Baquero, M. Diez-Fairen, C. Lage, S. García-Madrona, P. García-González, E. Alarcón-Martín, S. Valero, O. Sotolongo-Grau, A. Ullgren, AC. Naj, AW. Lemstra, A. Benaque, A. Pérez-Cordón, A. Benussi, A. Rábano, A. Padovani, A. Squassina, A. de Mendonça, A. Arias Pastor, AAL. Kok, A. Meggy, AB. Pastor, A. Espinosa, A. Corma-Gómez, A. Martín Montes, Á. Sanabria, AL. DeStefano, A. Schneider, A. Haapasalo, A. Kinhult Ståhlbom, A. Tybjærg-Hansen, AM. Hartmann, A. Spottke, A. Corbatón-Anchuelo, A. Rongve, B. Borroni, B. Arosio, B. Nacmias, BG. Nordestgaard, BW. Kunkle, C. Charbonnier, C. Abdelnour, C. Masullo, C. Martínez Rodríguez, C. Muñoz-Fernandez, C. Dufouil, C. Graff, CB. Ferreira, C. Chillotti, CA. Reynolds, C. Fenoglio, C. Van Broeckhoven, C. Clark, C. Pisanu, CL. Satizabal, C. Holmes, D. Buiza-Rueda, D. Aarsland, D. Rujescu, D. Alcolea, D. Galimberti, D. Wallon, D. Seripa, E. Grünblatt, E. Dardiotis, E. Düzel, E. Scarpini, E. Conti, E. Rubino, E. Gelpi, E. Rodriguez-Rodriguez, E. Duron, E. Boerwinkle, E. Ferri, F. Tagliavini, F. Küçükali, F. Pasquier, F. Sanchez-Garcia, F. Mangialasche, F. Jessen, G. Nicolas, G. Selbæk, G. Ortega, G. Chêne, G. Hadjigeorgiou, G. Rossi, G. Spalletta, G. Giaccone, G. Grande, G. Binetti, G. Papenberg, H. Hampel, H. Bailly, H. Zetterberg, H. Soininen, IK. Karlsson, I. Alvarez, I. Appollonio, I. Giegling, I. Skoog, I. Saltvedt, I. Rainero, I. Rosas Allende, J. Hort, J. Diehl-Schmid, J. Van Dongen, JS. Vidal, J. Lehtisalo, J. Wiltfang, JQ. Thomassen, J. Kornhuber, JL. Haines, J. Vogelgsang, JA. Pineda, J. Fortea, J. Popp, J. Deckert, K. Buerger, K. Morgan, K. Fließbach, K. Sleegers, L. Molina-Porcel, L. Kilander, L. Weinhold, LA. Farrer, LS. Wang, L. Kleineidam, L. Farotti, L. Parnetti, L. Tremolizzo, L. Hausner, L. Benussi, L. Froelich, MA. Ikram, MC. Deniz-Naranjo, M. Tsolaki, M. Rosende-Roca, M. Löwenmark, M. Hulsman, M. Spallazzi, MA. Pericak-Vance, M. Esiri, M. Bernal Sánchez-Arjona, MC. Dalmasso, MT. Martínez-Larrad, M. Arcaro, MM. Nöthen, M. Fernández-Fuertes, M. Dichgans, M. Ingelsson, MJ. Herrmann, M. Scherer, M. Vyhnalek, MH. Kosmidis, M. Yannakoulia, M. Schmid, M. Ewers, MT. Heneka, M. Wagner, M. Scamosci, M. Kivipelto, M. Hiltunen, M. Zulaica, M. Alegret, M. Fornage, N. Roberto, NM. van Schoor, NM. Seidu, N. Banaj, NJ. Armstrong, N. Scarmeas, N. Scherbaum, O. Goldhardt, O. Hanon, O. Peters, OA. Skrobot, O. Quenez, O. Lerch, P. Bossù, P. Caffarra, P. Dionigi Rossi, P. Sakka, P. Hoffmann, PA. Holmans, P. Fischer, P. Riederer, Q. Yang, R. Marshall, RN. Kalaria, R. Mayeux, R. Vandenberghe, R. Cecchetti, R. Ghidoni, R. Frikke-Schmidt, S. Sorbi, S. Hägg, S. Engelborghs, S. Helisalmi, S. Botne Sando, S. Kern, S. Archetti, S. Boschi, S. Fostinelli, S. Gil, S. Mendoza, S. Mead, S. Ciccone, S. Djurovic, S. Heilmann-Heimbach, S. Riedel-Heller, T. Kuulasmaa, T. Del Ser, T. Lebouvier, T. Polak, T. Ngandu, T. Grimmer, V. Bessi, V. Escott-Price, V. Giedraitis, V. Deramecourt, W. Maier, X. Jian, YAL. Pijnenburg, EADB contributors, GR@ACE study group, DEGESCO consortium, IGAP (ADGC, CHARGE, EADI, GERAD), PGC-ALZ consortia, PG. Kehoe, G. Garcia-Ribas, P. Sánchez-Juan, P. Pastor, J. Pérez-Tur, G. Piñol-Ripoll, A. Lopez de Munain, JM. García-Alberca, MJ. Bullido, V. Álvarez, A. Lleó, LM. Real, P. Mir, M. Medina, P. Scheltens, H. Holstege, M. Marquié, ME. Sáez, Á. Carracedo, P. Amouyel, GD. Schellenberg, J. Williams, S. Seshadri, CM. van Duijn, KA. Mather, R. Sánchez-Valle, M. Serrano-Ríos, A. Orellana, L. Tárraga, K. Blennow, M. Huisman, OA. Andreassen, D. Posthuma, J. Clarimón, M. Boada, WM. van der Flier, A. Ramirez, JC. Lambert, SJ. van der Lee, A. Ruiz
- 520 9_
- $a Genetic discoveries of Alzheimer's disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer's disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer's disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer's disease.
- 650 _2
- $a věk při počátku nemoci $7 D017668
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a senioři nad 80 let $7 D000369
- 650 _2
- $a Alzheimerova nemoc $x epidemiologie $x genetika $x patologie $7 D000544
- 650 _2
- $a amyloidový prekurzorový protein beta $x genetika $x metabolismus $7 D016564
- 650 _2
- $a apolipoproteiny E $x genetika $7 D001057
- 650 _2
- $a studie případů a kontrol $7 D016022
- 650 _2
- $a kohortové studie $7 D015331
- 650 _2
- $a datové soubory jako téma $7 D066264
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a následné studie $7 D005500
- 650 _2
- $a genetická predispozice k nemoci $7 D020022
- 650 _2
- $a celogenomová asociační studie $7 D055106
- 650 _2
- $a heterozygot $7 D006579
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 12
- $a multifaktoriální dědičnost $7 D020412
- 650 _2
- $a jednonukleotidový polymorfismus $7 D020641
- 650 _2
- $a hodnocení rizik $x metody $7 D018570
- 650 _2
- $a rizikové faktory $7 D012307
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a Research Support, N.I.H., Extramural $7 D052061
- 655 _2
- $a práce podpořená grantem $7 D013485
- 655 _2
- $a validační studie $7 D023361
- 700 1_
- $a Moreno-Grau, Sonia $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Tesi, Niccolo $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands $u Section Genomics of Neurodegenerative Diseases and Aging, Department of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands $u Delft Bioinformatics Lab, Delft Univeristy of Technology, Delft, The Netherlands
- 700 1_
- $a Grenier-Boley, Benjamin $u Univ. Lille, Inserm, Institut Pasteur de Lille, CHU Lille, U1167-Labex DISTALZ-RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
- 700 1_
- $a Andrade, Victor $u Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany
- 700 1_
- $a Jansen, Iris E $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands $u Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, The Netherlands
- 700 1_
- $a Pedersen, Nancy L $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
- 700 1_
- $a Stringa, Najada $u Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands
- 700 1_
- $a Zettergren, Anna $u Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), University of Gothenburg, Gothenburg, Sweden
- 700 1_
- $a Hernández, Isabel $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Montrreal, Laura $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain
- 700 1_
- $a Antúnez, Carmen $u Unidad de Demencias, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
- 700 1_
- $a Antonell, Anna $u Alzheimer's disease and other cognitive disorders unit. Service of Neurology, Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
- 700 1_
- $a Tankard, Rick M $u Mathematics and Statistics, Murdoch University, Perth, WA, Australia
- 700 1_
- $a Bis, Joshua C $u Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA
- 700 1_
- $a Sims, Rebecca $u Division of Psychological Medicine and Clinial Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK
- 700 1_
- $a Bellenguez, Céline $u Univ. Lille, Inserm, Institut Pasteur de Lille, CHU Lille, U1167-Labex DISTALZ-RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
- 700 1_
- $a Quintela, Inés $u Grupo de Medicina Xenómica, Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII), Universidade de Santiago de Compostela, Santiago de Compostela, Spain
- 700 1_
- $a González-Perez, Antonio $u CAEBI, Centro Andaluz de Estudios Bioinformáticos, Sevilla, Spain
- 700 1_
- $a Calero, Miguel $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u UFIEC, Instituto de Salud Carlos III, Madrid, Spain $u CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain
- 700 1_
- $a Franco-Macías, Emilio $u Unidad de Demencias, Servicio de Neurología y Neurofisiología, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain
- 700 1_
- $a Macías, Juan $u Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain
- 700 1_
- $a Blesa, Rafael $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, II B Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
- 700 1_
- $a Cervera-Carles, Laura $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, II B Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
- 700 1_
- $a Menéndez-González, Manuel $u Servicio de Neurología, Hospital Universitario Central de Asturias, Oviedo, Spain $u Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain $u Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain
- 700 1_
- $a Frank-García, Ana $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, La Paz University Hospital, Instituto de Investigación Sanitaria del Hospital Universitario La Paz, IdiPAZ, Madrid, Spain $u Hospital La Paz Institute for Health Research, IdiPAZ, Madrid, Spain $u Universidad Autónoma de Madrid, Madrid, Spain
- 700 1_
- $a Royo, Jose Luís $u Departamento de Especialidades Quirúrgicas, Bioquímicas e Inmunología, School of Medicine, University of Málaga, Málaga, Spain
- 700 1_
- $a Moreno, Fermin $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain $u Neurosciences Area, Instituto Biodonostia, San Sebastian, Spain
- 700 1_
- $a Huerto Vilas, Raquel $u Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain $u Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain
- 700 1_
- $a Baquero, Miquel $u Servei de Neurologia, Hospital Universitari i Politècnic La Fe, Valencia, Spain
- 700 1_
- $a Diez-Fairen, Mónica $u Fundació Docència i Recerca MútuaTerrassa, Terrassa, Barcelona, Spain $u Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain
- 700 1_
- $a Lage, Carmen $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain
- 700 1_
- $a García-Madrona, Sebastián $u Hospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain
- 700 1_
- $a García-González, Pablo $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain
- 700 1_
- $a Alarcón-Martín, Emilio $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u Departamento de Especialidades Quirúrgicas, Bioquímicas e Inmunología, School of Medicine, University of Málaga, Málaga, Spain
- 700 1_
- $a Valero, Sergi $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Sotolongo-Grau, Oscar $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain
- 700 1_
- $a Ullgren, Abbe $u Karolinska Institutet, Center for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Stockholm, Sweden $u Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital-Solna, Stockholm, Sweden
- 700 1_
- $a Naj, Adam C $u Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA $u Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
- 700 1_
- $a Lemstra, Afina W $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
- 700 1_
- $a Benaque, Alba $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain
- 700 1_
- $a Pérez-Cordón, Alba $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain
- 700 1_
- $a Benussi, Alberto $u Centre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
- 700 1_
- $a Rábano, Alberto $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain $u BT-CIEN, Madrid, Spain
- 700 1_
- $a Padovani, Alessandro $u Centre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
- 700 1_
- $a Squassina, Alessio $u Department of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy
- 700 1_
- $a de Mendonça, Alexandre $u Faculty of Medicine, University of Lisbon, Lisbon, Portugal
- 700 1_
- $a Arias Pastor, Alfonso $u Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain $u Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain
- 700 1_
- $a Kok, Almar A L $u Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands $u Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands
- 700 1_
- $a Meggy, Alun $u UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK
- 700 1_
- $a Pastor, Ana Belén $u CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain $u BT-CIEN, Madrid, Spain
- 700 1_
- $a Espinosa, Ana $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Corma-Gómez, Anaïs $u Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain
- 700 1_
- $a Martín Montes, Angel $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Hospital La Paz Institute for Health Research, IdiPAZ, Madrid, Spain $u Department of Neurology, La Paz University Hospital, Madrid, Spain
- 700 1_
- $a Sanabria, Ángela $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a DeStefano, Anita L $u Department of Neurology, Boston University School of Medicine, Boston, MA, USA $u Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
- 700 1_
- $a Schneider, Anja $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
- 700 1_
- $a Haapasalo, Annakaisa $u A.I Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
- 700 1_
- $a Kinhult Ståhlbom, Anne $u Karolinska Institutet, Center for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Stockholm, Sweden $u Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital-Solna, Stockholm, Sweden
- 700 1_
- $a Tybjærg-Hansen, Anne $u Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark $u Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- 700 1_
- $a Hartmann, Annette M $u Martin-Luther-University Halle-Wittenberg, University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Halle (Saale), Germany
- 700 1_
- $a Spottke, Annika $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany $u Department of Neurology, University of Bonn, Bonn, Germany
- 700 1_
- $a Corbatón-Anchuelo, Arturo $u Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain $u Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Madrid, Spain
- 700 1_
- $a Rongve, Arvid $u Haugesund Hospital, Helse Fonna, Department of Research and Innovation, Haugesund, Norway $u University of Bergen, Institute of Clinical Medicine (K1), Bergen, Norway
- 700 1_
- $a Borroni, Barbara $u Centre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
- 700 1_
- $a Arosio, Beatrice $u Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy $u Geriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
- 700 1_
- $a Nacmias, Benedetta $u Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence, Florence, Italy $u IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy
- 700 1_
- $a Nordestgaard, Børge G $u Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark $u Department of Clinical Biochemistry, Herlev Gentofte Hospital, Herlev, Denmark
- 700 1_
- $a Kunkle, Brian W $u Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA $u John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA
- 700 1_
- $a Charbonnier, Camille $u Normandie Univ, UNIROUEN, Inserm U1245, CHU Rouen, Department of Genetics and CNR-MAJ, FHU G4 Génomique, F-76000 Rouen, France
- 700 1_
- $a Abdelnour, Carla $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Masullo, Carlo $u Institute of Neurology, Catholic University of the Sacred Heart, School of Medicine, Milan, Italy
- 700 1_
- $a Martínez Rodríguez, Carmen $u Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain $u Hospital de Cabueñes, Gijón, Spain
- 700 1_
- $a Muñoz-Fernandez, Carmen $u Servicio de Neurología, Hospital Universitario de Gran Canaria Dr.Negrín, Las Palmas, Spain
- 700 1_
- $a Dufouil, Carole $u Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France $u CHU de Bordeaux, Pole de Santé Publique, Bordeaux, France
- 700 1_
- $a Graff, Caroline $u Karolinska Institutet, Center for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Stockholm, Sweden $u Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital-Solna, Stockholm, Sweden
- 700 1_
- $a Ferreira, Catarina B $u Instituto de Medicina Molecular João lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
- 700 1_
- $a Chillotti, Caterina $u Unit of Clinical Pharmacology, University Hospital of Cagliari, Cagliari, Italy
- 700 1_
- $a Reynolds, Chandra A $u Department of Psychology, University of California-Riverside, Riverside, CA, USA
- 700 1_
- $a Fenoglio, Chiara $u University of Milan, Dino Ferrari Center, Milan, Italy
- 700 1_
- $a Van Broeckhoven, Christine $u VIB Center for Molecular Neurology, Antwerp, Belgium $u Laboratory of Neurogenetics, Institute Born-Bunge, Antwerp, Belgium $u Department of Biomedical Sciences, University of Antwerp., Antwerp, Belgium
- 700 1_
- $a Clark, Christopher $u Insititute for Regenerative Medicine, University of Zürich, Zürich, Switzerland
- 700 1_
- $a Pisanu, Claudia $u Department of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy
- 700 1_
- $a Satizabal, Claudia L $u Department of Neurology, Boston University School of Medicine, Boston, MA, USA $u Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA $u Department of Population Health Sciences, UT Health San Antonio, San Antonio, TX, USA
- 700 1_
- $a Holmes, Clive $u Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK
- 700 1_
- $a Buiza-Rueda, Dolores $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain
- 700 1_
- $a Aarsland, Dag $u Department of Old Age Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK $u Centre of Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway
- 700 1_
- $a Rujescu, Dan $u Martin-Luther-University Halle-Wittenberg, University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Halle (Saale), Germany
- 700 1_
- $a Alcolea, Daniel $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, II B Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
- 700 1_
- $a Galimberti, Daniela $u University of Milan, Dino Ferrari Center, Milan, Italy $u Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, Italy
- 700 1_
- $a Wallon, David $u Normandie Univ, UNIROUEN, Inserm U1245, CHU Rouen, Department of Neurology and CNR-MAJ, FHU G4 Génomique, F-76000 Rouen, France
- 700 1_
- $a Seripa, Davide $u Complex Structure of Geriatrics, Department of Medical Sciences Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
- 700 1_
- $a Grünblatt, Edna $u Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital Zurich (PUK), University of Zurich, Zurich, Switzerland $u Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland $u Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
- 700 1_
- $a Dardiotis, Efthimios $u School of Medicine, University of Thessaly, Larissa, Greece
- 700 1_
- $a Düzel, Emrah $u German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany $u Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany
- 700 1_
- $a Scarpini, Elio $u University of Milan, Dino Ferrari Center, Milan, Italy $u Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, Italy
- 700 1_
- $a Conti, Elisa $u School of Medicine and Surgery, University of Milano-Bicocca and Milan Center for Neuroscience, Milan, Italy
- 700 1_
- $a Rubino, Elisa $u Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Torino, Italy
- 700 1_
- $a Gelpi, Ellen $u Neurological Tissue Bank of the Biobanc-Hospital Clinic-IDIBAPS, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain $u Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria
- 700 1_
- $a Rodriguez-Rodriguez, Eloy $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain
- 700 1_
- $a Duron, Emmanuelle $u APHP, Hôpital Brousse, equipe INSERM 1178, MOODS, Villejuif, France $u Université Paris-Saclay, UVSQ, Inserm, CESP, Team MOODS, Le Kremlin-Bicêtre, Paris, France $u APHP, Hôpital Broca, Paris, France
- 700 1_
- $a Boerwinkle, Eric $u School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA $u Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA
- 700 1_
- $a Ferri, Evelyn $u Geriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
- 700 1_
- $a Tagliavini, Fabrizio $u Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
- 700 1_
- $a Küçükali, Fahri $u VIB Center for Molecular Neurology, Antwerp, Belgium $u Laboratory of Neurogenetics, Institute Born-Bunge, Antwerp, Belgium $u Department of Biomedical Sciences, University of Antwerp., Antwerp, Belgium
- 700 1_
- $a Pasquier, Florence $u Inserm U1172, CHU, DISTAlz, LiCEND, Univ Lille, Lille, France $u CHU CNR-MAJ, Lille, France
- 700 1_
- $a Sanchez-Garcia, Florentino $u Servicio de Inmunología, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain
- 700 1_
- $a Mangialasche, Francesca $u Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden
- 700 1_
- $a Jessen, Frank $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany $u Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany $u Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany
- 700 1_
- $a Nicolas, Gaël $u Hospital de Cabueñes, Gijón, Spain
- 700 1_
- $a Selbæk, Geir $u Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway $u Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway $u Institute of Clinical Medicine, University of Oslo, Oslo, Norway
- 700 1_
- $a Ortega, Gemma $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Chêne, Geneviève $u Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France $u CHU de Bordeaux, Pole de Santé Publique, Bordeaux, France
- 700 1_
- $a Hadjigeorgiou, Georgios $u Department of Neurology, Medical School, University of Cyprus, Nicosia, Cyprus
- 700 1_
- $a Rossi, Giacomina $u Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
- 700 1_
- $a Spalletta, Gianfranco $u Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy $u Beth K. and Stuart C. Yudofsky Division of Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA
- 700 1_
- $a Giaccone, Giorgio $u Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
- 700 1_
- $a Grande, Giulia $u Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
- 700 1_
- $a Binetti, Giuliano $u MAC-Memory Clinic, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy $u Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
- 700 1_
- $a Papenberg, Goran $u Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
- 700 1_
- $a Hampel, Harald $u Sorbonne University, GRC n° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Paris, France
- 700 1_
- $a Bailly, Henri $u APHP, Hôpital Broca, Paris, France $u EA 4468, Sorbonne Paris Cité, Université Paris Descartes, Paris, France
- 700 1_
- $a Zetterberg, Henrik $u Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden $u Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden $u Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK $u UK Dementia Research Institute at UCL, London, UK
- 700 1_
- $a Soininen, Hilkka $u Institute of Clinical Medicine Neurology, University of Eastern Finland, Kuopio, Finland $u Neurocenter, neurology, Kuopio University Hospital, Kuopio, Finland
- 700 1_
- $a Karlsson, Ida K $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden $u Institute for Gerontology and Aging Research Network-Jönköping (ARN-J), School of Health and Welfare, Jönköping University, Jönköping, Sweden
- 700 1_
- $a Alvarez, Ignacio $u Fundació Docència i Recerca MútuaTerrassa, Terrassa, Barcelona, Spain $u Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain
- 700 1_
- $a Appollonio, Ildebrando $u School of Medicine and Surgery, University of Milano-Bicocca and Milan Center for Neuroscience, Milan, Italy $u Neurology Unit, 'San Gerardo' hospital, Monza, Italy
- 700 1_
- $a Giegling, Ina $u Martin-Luther-University Halle-Wittenberg, University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Halle (Saale), Germany
- 700 1_
- $a Skoog, Ingmar $u Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), University of Gothenburg, Gothenburg, Sweden
- 700 1_
- $a Saltvedt, Ingvild $u Department of Geriatrics, Clinic of Medicine, St Olavs Hospital, University Hospital of Trondheim, Trondheim, Norway $u Department of Neuromedicine and Movement Science, Norwegian University of Science and Technhology (NTNU), Trondheim, Norway
- 700 1_
- $a Rainero, Innocenzo $u Department of Neuroscience "Rita Levi Montalcini", University of Torino, Torino, Italy
- 700 1_
- $a Rosas Allende, Irene $u Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain $u Laboratorio de Genética, Hospital Universitario Central de Asturias, Oviedo, Spain
- 700 1_
- $a Hort, Jakub $u Memory Clinic, Department of Neurology, 2nd Faculty of Medicine and Motol University Hospital, Charles University, Prague, Czech Republic $u International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic
- 700 1_
- $a Diehl-Schmid, Janine $u Department of Psychiatry and Psychotherapy, School of Medicine Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
- 700 1_
- $a Van Dongen, Jasper $u VIB Center for Molecular Neurology, Antwerp, Belgium $u Laboratory of Neurogenetics, Institute Born-Bunge, Antwerp, Belgium
- 700 1_
- $a Vidal, Jean-Sebastien $u APHP, Hôpital Broca, Paris, France $u EA 4468, Sorbonne Paris Cité, Université Paris Descartes, Paris, France
- 700 1_
- $a Lehtisalo, Jenni $u Institute of Clinical Medicine Neurology, University of Eastern Finland, Kuopio, Finland $u Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
- 700 1_
- $a Wiltfang, Jens $u Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany $u German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany $u Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Aveiro, Portugal
- 700 1_
- $a Thomassen, Jesper Qvist $u Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
- 700 1_
- $a Kornhuber, Johannes $u Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
- 700 1_
- $a Haines, Jonathan L $u Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA $u Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA
- 700 1_
- $a Vogelgsang, Jonathan $u Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany $u Translational Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, MA, USA
- 700 1_
- $a Pineda, Juan A $u Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain
- 700 1_
- $a Fortea, Juan $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, II B Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
- 700 1_
- $a Popp, Julius $u Department of Geriatric Psychiatry, University Hospital of Psychiatry Zürich, Zürich, Switzerland $u University of Zürich, Zürich, Switzerland $u Old age Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
- 700 1_
- $a Deckert, Jürgen $u Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital, Wuerzburg, Germany
- 700 1_
- $a Buerger, Katharina $u Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany $u German Center for Neurodegenerative Diseases (DZNE), Munich, Germany
- 700 1_
- $a Morgan, Kevin $u Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, UK
- 700 1_
- $a Fließbach, Klaus $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany
- 700 1_
- $a Sleegers, Kristel $u VIB Center for Molecular Neurology, Antwerp, Belgium $u Laboratory of Neurogenetics, Institute Born-Bunge, Antwerp, Belgium $u Department of Biomedical Sciences, University of Antwerp., Antwerp, Belgium
- 700 1_
- $a Molina-Porcel, Laura $u Alzheimer's disease and other cognitive disorders unit. Service of Neurology, Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain $u Neurological Tissue Bank of the Biobanc-Hospital Clinic-IDIBAPS, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
- 700 1_
- $a Kilander, Lena $u Department of Public Health and Caring Sciences/Geriatrics, Uppsala, Sweden
- 700 1_
- $a Weinhold, Leonie $u Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany
- 700 1_
- $a Farrer, Lindsay A $u Departments of Medicine (Biomedical Genetics), Neurology, Ophthalmology, Epidemiology, and Biostatistics, Boston University Schools of Medicine and Public Health, Boston, MA, USA
- 700 1_
- $a Wang, Li-San $u Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
- 700 1_
- $a Kleineidam, Luca $u Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany
- 700 1_
- $a Farotti, Lucia $u Centre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy
- 700 1_
- $a Parnetti, Lucilla $u Centre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy
- 700 1_
- $a Tremolizzo, Lucio $u School of Medicine and Surgery, University of Milano-Bicocca and Milan Center for Neuroscience, Milan, Italy $u Neurology Unit, 'San Gerardo' hospital, Monza, Italy
- 700 1_
- $a Hausner, Lucrezia $u Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany
- 700 1_
- $a Benussi, Luisa $u Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
- 700 1_
- $a Froelich, Lutz $u Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany
- 700 1_
- $a Ikram, M Arfan $u Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
- 700 1_
- $a Deniz-Naranjo, M Candida $u Servicio de Inmunología, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain
- 700 1_
- $a Tsolaki, Magda $u 1st Department of Neurology Aristotle University of Thessaloniki, Thessaloniki, Greece
- 700 1_
- $a Rosende-Roca, Maitée $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Löwenmark, Malin $u Department of Public Health and Caring Sciences/Geriatrics, Uppsala, Sweden
- 700 1_
- $a Hulsman, Marc $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands $u Section Genomics of Neurodegenerative Diseases and Aging, Department of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
- 700 1_
- $a Spallazzi, Marco $u Azienda Ospedaliero-Universitaria, Parma, Italy
- 700 1_
- $a Pericak-Vance, Margaret A $u John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA
- 700 1_
- $a Esiri, Margaret $u Nuffield Department of Clinical Neurosciences, Oxford, UK
- 700 1_
- $a Bernal Sánchez-Arjona, María $u Unidad de Demencias, Servicio de Neurología y Neurofisiología, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain
- 700 1_
- $a Dalmasso, Maria Carolina $u Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany
- 700 1_
- $a Martínez-Larrad, María Teresa $u Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain $u Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Madrid, Spain
- 700 1_
- $a Arcaro, Marina $u Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, Italy
- 700 1_
- $a Nöthen, Markus M $u Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany
- 700 1_
- $a Fernández-Fuertes, Marta $u Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain
- 700 1_
- $a Dichgans, Martin $u Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany $u German Center for Neurodegenerative Diseases (DZNE), Munich, Germany $u Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
- 700 1_
- $a Ingelsson, Martin $u Department of Public Health and Caring Sciences/Geriatrics, Uppsala, Sweden
- 700 1_
- $a Herrmann, Martin J $u Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital, Wuerzburg, Germany
- 700 1_
- $a Scherer, Martin $u Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany
- 700 1_
- $a Vyhnalek, Martin $u Memory Clinic, Department of Neurology, 2nd Faculty of Medicine and Motol University Hospital, Charles University, Prague, Czech Republic $u International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic
- 700 1_
- $a Kosmidis, Mary H $u Laboratory of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece
- 700 1_
- $a Yannakoulia, Mary $u Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
- 700 1_
- $a Schmid, Matthias $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany $u Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany
- 700 1_
- $a Ewers, Michael $u Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany $u German Center for Neurodegenerative Diseases (DZNE), Munich, Germany
- 700 1_
- $a Heneka, Michael T $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
- 700 1_
- $a Wagner, Michael $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
- 700 1_
- $a Scamosci, Michela $u Institute of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy
- 700 1_
- $a Kivipelto, Miia $u Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden $u Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland $u Neuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, UK $u Stockholms Sjukhem, Research & Development Unit, Stockholm, Sweden
- 700 1_
- $a Hiltunen, Mikko $u Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
- 700 1_
- $a Zulaica, Miren $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Neurosciences Area, Instituto Biodonostia, San Sebastian, Spain
- 700 1_
- $a Alegret, Montserrat $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Fornage, Myriam $u Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA
- 700 1_
- $a Roberto, Natalia $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain
- 700 1_
- $a van Schoor, Natasja M $u Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands
- 700 1_
- $a Seidu, Nazib M $u Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), University of Gothenburg, Gothenburg, Sweden
- 700 1_
- $a Banaj, Nerisa $u Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy
- 700 1_
- $a Armstrong, Nicola J $u Mathematics and Statistics, Murdoch University, Perth, WA, Australia
- 700 1_
- $a Scarmeas, Nikolaos $u 1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece $u Taub Institute for Research in Alzheimer's Disease and the Aging Brain, The Gertrude H. Sergievsky Center, Depatment of Neurology, Columbia University, New York, NY, USA
- 700 1_
- $a Scherbaum, Norbert $u LVR-Hospital Essen, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Duisburg-Essen, Essen, Germany
- 700 1_
- $a Goldhardt, Oliver $u Department of Psychiatry and Psychotherapy, School of Medicine Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
- 700 1_
- $a Hanon, Oliver $u APHP, Hôpital Broca, Paris, France $u EA 4468, Sorbonne Paris Cité, Université Paris Descartes, Paris, France
- 700 1_
- $a Peters, Oliver $u Department of Psychiatry and Psychotherapy and Experimental and Clinical Research Center (ECRC), Charité-Universitätsmedizin Berlin, Berlin, Germany $u German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany
- 700 1_
- $a Skrobot, Olivia Anna $u Bristol Medical School (THS), University of Bristol, Southmead Hospital, Bristol, UK
- 700 1_
- $a Quenez, Olivier $u Normandie Univ, UNIROUEN, Inserm U1245, CHU Rouen, Department of Genetics and CNR-MAJ, FHU G4 Génomique, F-76000 Rouen, France
- 700 1_
- $a Lerch, Ondrej $u Memory Clinic, Department of Neurology, 2nd Faculty of Medicine and Motol University Hospital, Charles University, Prague, Czech Republic $u International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic
- 700 1_
- $a Bossù, Paola $u Experimental Neuro-psychobiology Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy
- 700 1_
- $a Caffarra, Paolo $u Unit of Neuroscience, DIMEC, University of Parma, Parma, Italy
- 700 1_
- $a Dionigi Rossi, Paolo $u Geriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
- 700 1_
- $a Sakka, Paraskevi $u Athens Association of Alzheimer's disease and Related Disorders, Athens, Greece
- 700 1_
- $a Hoffmann, Per $u Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany $u Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
- 700 1_
- $a Holmans, Peter A $u Division of Psychological Medicine and Clinial Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK
- 700 1_
- $a Fischer, Peter $u Department of Psychiatry, Social Medicine Center East- Donauspital, Vienna, Austria
- 700 1_
- $a Riederer, Peter $u Center of Mental Health, Clinic and Policlinic of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Würzburg, Germany
- 700 1_
- $a Yang, Qiong $u Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
- 700 1_
- $a Marshall, Rachel $u Division of Psychological Medicine and Clinial Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK
- 700 1_
- $a Kalaria, Rajesh N $u Translational and Clincial Research Institute, Newcastle University, Newcastle upon Tyne, UK $u Campus for Ageing anf Vitality, Newcastle upon Tyne, UK
- 700 1_
- $a Mayeux, Richard $u Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA $u Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA $u Department of Neurology, Columbia University, New York, NY, USA
- 700 1_
- $a Vandenberghe, Rik $u Laboratory for Cognitive Neurology, Department of Neurosciences, University of Leuven, Leuven, Belgium $u Neurology Department, University Hospitals Leuven, Leuven, Belgium
- 700 1_
- $a Cecchetti, Roberta $u Institute of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy
- 700 1_
- $a Ghidoni, Roberta $u Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
- 700 1_
- $a Frikke-Schmidt, Ruth $u Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark $u Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- 700 1_
- $a Sorbi, Sandro $u Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence, Florence, Italy $u IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy
- 700 1_
- $a Hägg, Sara $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
- 700 1_
- $a Engelborghs, Sebastiaan $u Center for Neurosciences, Vrije Universiteit Brussel (VUB), Brussels, Belgium $u Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium $u Institute Born-Bunge, University of Antwerp, Antwerp, Belgium $u Department of Neurology, VUB University Hospital Brussels (UZ Brussel), Brussels, Belgium
- 700 1_
- $a Helisalmi, Seppo $u Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland
- 700 1_
- $a Botne Sando, Sigrid $u Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway $u Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
- 700 1_
- $a Kern, Silke $u Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), University of Gothenburg, Gothenburg, Sweden
- 700 1_
- $a Archetti, Silvana $u Department of Laboratory Diagnostics, III Laboratory of Analysis, Brescia Hospital, Brescia, Italy
- 700 1_
- $a Boschi, Silvia $u Department of Neuroscience "Rita Levi Montalcini", University of Torino, Torino, Italy
- 700 1_
- $a Fostinelli, Silvia $u Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
- 700 1_
- $a Gil, Silvia $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain
- 700 1_
- $a Mendoza, Silvia $u Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain
- 700 1_
- $a Mead, Simon $u MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK
- 700 1_
- $a Ciccone, Simona $u Geriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
- 700 1_
- $a Djurovic, Srdjan $u Department of Medical Genetics, Oslo University Hospital, Oslo, Norway $u NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway
- 700 1_
- $a Heilmann-Heimbach, Stefanie $u Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany
- 700 1_
- $a Riedel-Heller, Steffi $u Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany
- 700 1_
- $a Kuulasmaa, Teemu $u Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
- 700 1_
- $a Del Ser, Teodoro $u Department of Neurology/CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain
- 700 1_
- $a Lebouvier, Thibaud $u Inserm U1172, CHU, DISTAlz, LiCEND, Univ Lille, Lille, France $u CHU CNR-MAJ, Lille, France
- 700 1_
- $a Polak, Thomas $u Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital, Wuerzburg, Germany
- 700 1_
- $a Ngandu, Tiia $u Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden $u Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
- 700 1_
- $a Grimmer, Timo $u Department of Psychiatry and Psychotherapy, School of Medicine Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
- 700 1_
- $a Bessi, Valentina $u Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence, Florence, Italy $u Azienda Ospedaliero-Universitaria Careggi Largo Brambilla, Florence, Italy
- 700 1_
- $a Escott-Price, Valentina $u Division of Psychological Medicine and Clinial Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK $u UKDRI Cardiff, Cardiff University, Cardiff, UK
- 700 1_
- $a Giedraitis, Vilmantas $u Department of Public Health and Caring Sciences/Geriatrics, Uppsala, Sweden
- 700 1_
- $a Deramecourt, Vincent $u Inserm U1172, CHU, DISTAlz, LiCEND, Univ Lille, Lille, France $u CHU CNR-MAJ, Lille, France
- 700 1_
- $a Maier, Wolfgang $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
- 700 1_
- $a Jian, Xueqiu $u Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA
- 700 1_
- $a Pijnenburg, Yolande A L $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
- 700 1_
- $a Kehoe, Patrick Gavin $u German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany
- 700 1_
- $a Garcia-Ribas, Guillermo $u Hospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain
- 700 1_
- $a Sánchez-Juan, Pascual $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain
- 700 1_
- $a Pastor, Pau $u Fundació Docència i Recerca MútuaTerrassa, Terrassa, Barcelona, Spain $u Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain
- 700 1_
- $a Pérez-Tur, Jordi $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain $u Unidad Mixta de Neurologia Genètica, Instituto de Investigación Sanitaria La Fe, Valencia, Spain
- 700 1_
- $a Piñol-Ripoll, Gerard $u Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain $u Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain
- 700 1_
- $a Lopez de Munain, Adolfo $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain $u Neurosciences Area, Instituto Biodonostia, San Sebastian, Spain $u Department of Neurosciences, Faculty of Medicine and Nursery, University of the Basque Country, San Sebastián, Spain
- 700 1_
- $a García-Alberca, Jose María $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain
- 700 1_
- $a Bullido, María J $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Universidad Autónoma de Madrid, Madrid, Spain $u Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain $u Instituto de Investigacion Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain
- 700 1_
- $a Álvarez, Victoria $u Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain $u Laboratorio de Genética, Hospital Universitario Central de Asturias, Oviedo, Spain
- 700 1_
- $a Lleó, Alberto $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, II B Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
- 700 1_
- $a Real, Luis M $u Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain $u Departamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina, Universidad de Málaga, Málaga, Spain
- 700 1_
- $a Mir, Pablo $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain
- 700 1_
- $a Medina, Miguel $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain
- 700 1_
- $a Scheltens, Philip $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
- 700 1_
- $a Holstege, Henne $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands $u Section Genomics of Neurodegenerative Diseases and Aging, Department of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
- 700 1_
- $a Marquié, Marta $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Sáez, María Eugenia $u CAEBI, Centro Andaluz de Estudios Bioinformáticos, Sevilla, Spain
- 700 1_
- $a Carracedo, Ángel $u Grupo de Medicina Xenómica, Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII), Universidade de Santiago de Compostela, Santiago de Compostela, Spain $u Fundación Pública Galega de Medicina Xenómica-CIBERER-IDIS, Santiago de Compostela, Spain
- 700 1_
- $a Amouyel, Philippe $u Univ. Lille, Inserm, Institut Pasteur de Lille, CHU Lille, U1167-Labex DISTALZ-RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
- 700 1_
- $a Schellenberg, Gerard D $u Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
- 700 1_
- $a Williams, Julie $u Division of Psychological Medicine and Clinial Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK $u UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK
- 700 1_
- $a Seshadri, Sudha $u Department of Neurology, Boston University School of Medicine, Boston, MA, USA $u Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA $u Framingham Heart Study, Framingham, MA, USA
- 700 1_
- $a van Duijn, Cornelia M $u Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands $u Nuffield Department of Population Health, University of Oxford, Oxford, UK
- 700 1_
- $a Mather, Karen A $u Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia $u Neuroscience Research Australia, Sydney, NSW, Australia
- 700 1_
- $a Sánchez-Valle, Raquel $u Alzheimer's disease and other cognitive disorders unit. Service of Neurology, Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
- 700 1_
- $a Serrano-Ríos, Manuel $u Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain $u Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Madrid, Spain
- 700 1_
- $a Orellana, Adelina $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Tárraga, Lluís $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a Blennow, Kaj $u Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden $u Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
- 700 1_
- $a Huisman, Martijn $u Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands $u Department of Sociology, VU University, Amsterdam, The Netherlands
- 700 1_
- $a Andreassen, Ole A $u NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway $u Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
- 700 1_
- $a Posthuma, Danielle $u Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, The Netherlands
- 700 1_
- $a Clarimón, Jordi $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain $u Department of Neurology, II B Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
- 700 1_
- $a Boada, Mercè $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain
- 700 1_
- $a van der Flier, Wiesje M $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
- 700 1_
- $a Ramirez, Alfredo $u Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany $u Department of Neurodegenerative diseases and Geriatric Psychiatry, University Clinic Bonn, Bonn, Germany $u German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany $u Department of Psychiatry, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA
- 700 1_
- $a Lambert, Jean-Charles $u Univ. Lille, Inserm, Institut Pasteur de Lille, CHU Lille, U1167-Labex DISTALZ-RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
- 700 1_
- $a van der Lee, Sven J $u Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands. s.j.vanderlee@amsterdamumc.nl $u Section Genomics of Neurodegenerative Diseases and Aging, Department of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands. s.j.vanderlee@amsterdamumc.nl
- 700 1_
- $a Ruiz, Agustín $u Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain. aruiz@fundacioace.org $u CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain. aruiz@fundacioace.org
- 710 2_
- $a EADB contributors
- 710 2_
- $a GR@ACE study group
- 710 2_
- $a DEGESCO consortium
- 710 2_
- $a IGAP (ADGC, CHARGE, EADI, GERAD)
- 710 2_
- $a PGC-ALZ consortia
- 773 0_
- $w MED00184850 $t Nature communications $x 2041-1723 $g Roč. 12, č. 1 (2021), s. 3417
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/34099642 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20210728 $b ABA008
- 991 __
- $a 20210830100041 $b ABA008
- 999 __
- $a ok $b bmc $g 1689537 $s 1138911
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2021 $b 12 $c 1 $d 3417 $e 20210607 $i 2041-1723 $m Nature communications $n Nat Commun $x MED00184850
- GRA __
- $a U24 AG021886 $p NIA NIH HHS $2 United States
- GRA __
- $a U01 AG032984 $p NIA NIH HHS $2 United States
- GRA __
- $a U01 AG016976 $p NIA NIH HHS $2 United States
- GRA __
- $a N01AG12100 $p NIA NIH HHS $2 United States
- GRA __
- $a U01 AG058589 $p NIA NIH HHS $2 United States
- GRA __
- $a 082604/2/07/Z $p Wellcome Trust $2 United Kingdom
- GRA __
- $p Wellcome Trust $2 United Kingdom
- GRA __
- $a U01 AG049505 $p NIA NIH HHS $2 United States
- GRA __
- $a R01 HL105756 $p NHLBI NIH HHS $2 United States
- GRA __
- $a 503480 $p Medical Research Council $2 United Kingdom
- LZP __
- $a Pubmed-20210728
