Amplification of tick-borne encephalitis virus infection during co-feeding of ticks
Jazyk angličtina Země Velká Británie, Anglie Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- arachnida jako vektory mikrobiologie MeSH
- klíšťata mikrobiologie MeSH
- klíšťová encefalitida přenos MeSH
- larva mikrobiologie MeSH
- lidé MeSH
- morčata MeSH
- myši MeSH
- nymfa mikrobiologie MeSH
- plakové testy MeSH
- polymerázová řetězová reakce MeSH
- replikace viru MeSH
- RNA virová analýza MeSH
- viry klíšťové encefalitidy genetika fyziologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- morčata MeSH
- mužské pohlaví MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- RNA virová MeSH
Following engorgement of Rhipicephalus appendiculatus larvae on guinea-pigs infected with tick-borne encephalitis (TBE) virus, none of the engorged larvae or emergent nymphs contained detectable infectious virus. However, one of twelve pools, each containing three of the unfed nymphs, was positive when screened by polymerase chain reaction (PCR), indicating a low prevalence of TBE virus infection in the unfed nymphs. After engorgement of the nymphs on four uninfected guinea-pigs, 19/24 (79%) fed nymphs from one guinea-pig and 4/25 (16%) fed nymphs from a second guinea-pig were infected; all the ticks examined from the other two guinea-pigs were uninfected. The results suggest that TBE virus was transmitted from a low proportion of infected nymphs (infected as larvae) to uninfected nymphs as they fed together on an uninfected guinea-pig. Such amplification of the initial infection, at the population level, could play an important role in maintaining TBE virus infections in nature, particularly if there is a low level of vertical transmission from one tick generation to the next.
Citace poskytuje Crossref.org
Fitness of mCherry Reporter Tick-Borne Encephalitis Virus in Tick Experimental Models
History of Arbovirus Research in the Czech Republic
