Traditionally, living organisms have often been classified into two main categories: unicellular and multicellular. In recent years, however, the boundary between these two groups has become less strict and clear than was previously presumed. Studies on the communities formed by unicellular microorganisms have revealed that various properties and processes so far mainly associated with metazoa are also important for the proper development, survival and behaviour of muticellular microbial populations. In this review, we present various examples of this, using a yeast colony as representative of a structured organized microbial community. Among other things, we will show how the differentiation of yeast cells within a colony can be important for the long-term survival of a community under conditions of nutrient shortage, how colony development and physiology can be influenced by the environment, and how a group of colonies can synchronize their developmental changes. In the last section, we introduce examples of molecular mechanisms that can participate in some aspects of the behaviour of yeast populations.

Department of Genetics and Microbiology Charles University Prague Czech Republic

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Non-Coding RNAs: Regulators of Stress, Ageing, and Developmental Decisions in Yeast?

Cyc8p and Tup1p transcription regulators antagonistically regulate Flo11p expression and complexity of yeast colony biofilms

Long Noncoding RNAs in Yeast Cells and Differentiated Subpopulations of Yeast Colonies and Biofilms

Transcriptome Remodeling of Differentiated Cells during Chronological Ageing of Yeast Colonies: New Insights into Metabolic Differentiation

Metabolic differentiation of surface and invasive cells of yeast colony biofilms revealed by gene expression profiling

Rapidly developing yeast microcolonies differentiate in a similar way to aging giant colonies

Reactive oxygen species in the signaling and adaptation of multicellular microbial communities

Yeast colony survival depends on metabolic adaptation and cell differentiation rather than on stress defense