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Intravenous Thrombolysis for Stroke Recurring Within 3 Months From the Previous Event
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Karlinski, Michal
Author Karlinski, Michal From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Kobayashi, Adam
Author Kobayashi, Adam From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Czlonkowska, Anna
Author Czlonkowska, Anna From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.). czlonkow
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Mikulik, Robert
Author Mikulik, Robert From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Vaclavik, Daniel
Author Vaclavik, Daniel From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Brozman, Miroslav
Author Brozman, Miroslav From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Gdovinova, Zuzana
Author Gdovinova, Zuzana From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Švigelj, Viktor
Author Švigelj, Viktor From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Csiba, Laszlo
Author Csiba, Laszlo From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Fekete, Klara
Author Fekete, Klara From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Kõrv, Janika
Author Kõrv, Janika From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Demarin, Vida
Author Demarin, Vida From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Bašic-Kes, Vanja
Author Bašic-Kes, Vanja From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Vilionskis, Aleksandras
Author Vilionskis, Aleksandras From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Jatuzis, Dalius
Author Jatuzis, Dalius From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Krespi, Yakup
Author Krespi, Yakup From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Shamalov, Nikolay
Author Shamalov, Nikolay From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Andonova, Silva
Author Andonova, Silva From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Ahmed, Niaz
Author Ahmed, Niaz From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
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Wahlgren, Nils
Author Wahlgren, Nils From the 2nd Department of Neurology (M.K., A.K., A.C.), and Interventional Stroke and Cerebrovascular Treatment Centre (A.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (A.C.); International Clinical Research Center and Neurology Department, St Anne's Hospital in Brno and Masaryk University, Brno, Czech Republic (R.M.); Neurology Department, Ostava-Vítkovice Hospital, Research and Training Institute, Ostrava Czech Republic (D.V.); Neurology Department, University Hospital Nitra, Constantin Philosopher University, Nitra, Slovakia (M.B.); Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia (Z.G.); Department of Vascular Neurology and Neurological Intensive Care, University Medical Centre Ljubljana and Zdravstveni Nasveti, Slovenia (V.Š.); Department of Neurology, Medical and Health Science Center, University of Debrecen, Hungary (L.C., K.F.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K.); Medical Center Aviva, Zagreb, Croatia (V.D.); Department of Neurology, University Hospital "Sestre Milosrdnice", Zagreb, Croatia (V.B.-K.); Department of Neurology and Neurosurgery, Vilnius University and Republican Vilnius University Hospital, Lithuania (A.V.); Department of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University and Vilnius University Hospital Santariskiu Clinics, Lithuania (D.J.); Stroke Rehabilitation and Research Center, Memorial Sisli Hospital, Memorial Health Group Stroke Center, Istanbul, Turkey (Y.K.); Department of Neurology and Neurosurgery, Pirogov Russian National Medical University, Moscow, Russia (N.S.); Department of Neurological Diseases, Faculty of Medicine, Medical University of Varna, Bulgaria (S.A.); and Department of Neurology, Karolinska University Hospital, Solna and Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden (N.A., N.W.)
- Safe Implementation of Treatments in Stroke–East Registry (SITS-EAST) Investigators
Language English Country United States Media print-electronic
Document type Clinical Study, Journal Article, Research Support, Non-U.S. Gov't
Persistent link
https://www.medvik.cz/link/pmid26451024
Links
PubMed
26451024
DOI
10.1161/strokeaha.115.010420
PII: STROKEAHA.115.010420
Knihovny.cz E-resources
- Keywords
- acute stroke, alteplase, off-label use, recurrence, thrombolysis, treatment outcome,
- MeSH
- Time Factors MeSH
- Cerebral Hemorrhage chemically induced MeSH
- Stroke drug therapy epidemiology etiology MeSH
- Fibrinolytic Agents therapeutic use MeSH
- Hyperlipidemias epidemiology MeSH
- Hypertension epidemiology MeSH
- Administration, Intravenous MeSH
- Brain Ischemia complications drug therapy epidemiology MeSH
- Cohort Studies MeSH
- Middle Aged MeSH
- Humans MeSH
- Recurrence MeSH
- Retrospective Studies MeSH
- Aged MeSH
- Tissue Plasminogen Activator therapeutic use MeSH
- Thrombolytic Therapy methods MeSH
- Patient Selection MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Clinical Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Fibrinolytic Agents MeSH
- Tissue Plasminogen Activator MeSH
BACKGROUND AND PURPOSE: According to the European license, alteplase can be given no sooner than 3 months after previous stroke. However, it is not known whether past history of stroke influences the effect of treatment. Our aim was to evaluate safety and functional outcome after intravenous thrombolysis administered in everyday practice to patients with previous stroke≤3 months compared with those with first-ever stroke. METHODS: We analyzed consecutive cases treated with alteplase between October 2003 and July 2014 contributed to the Safe Implementation of Thrombolysis for Stroke-Eastern Europe registry from 12 countries. Odds ratios were calculated using unadjusted and adjusted logistic regression. RESULTS: Of 13,007 patients, 11,221 (86%) had no history of stroke and 249 (2%) experienced previous stroke≤3 months before admission. Patients with previous stroke≤3 months had a higher proportion of hypertension and hyperlipidemia. There were no significant differences in outcome, including symptomatic intracerebral hemorrhage according to European Cooperative Acute Stroke Study (unadjusted odds ratio 1.27, 95% confidence interval: 0.74-2.15), and being alive and independent at 3 months (odds ratio 0.81, 95% confidence interval: 0.61-1.09). CONCLUSIONS: Patients currently treated with alteplase, despite a history of previous stroke≤3 months, do not seem to achieve worse outcome than those with first-ever stroke. Although careful patient selection was probably of major importance, our findings provide reassurance that this group of patients may safely benefit from thrombolysis and should not be arbitrarily excluded as a whole. Further studies are needed to identify the shortest safe time lapse from the previous event to treatment with alteplase.
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