Prevalence and Imaging Characteristics of Nonmyelopathic and Myelopathic Spondylotic Cervical Cord Compression

. 2016 Dec 15 ; 41 (24) : 1908-1916.

Jazyk angličtina Země Spojené státy americké Médium print

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid27509189
Odkazy

PubMed 27509189
DOI 10.1097/brs.0000000000001842
PII: 00007632-201612150-00012
Knihovny.cz E-zdroje

STUDY DESIGN: Cross-sectional population-based observational study. OBJECTIVE: To estimate the prevalence of nonmyelopathic spondylotic cervical cord compression (NMSCCC) and cervical spondylotic myelopathy (CSM) in a population older than 40 years and to evaluate the magnetic resonance imaging (MRI) characteristics of these conditions. SUMMARY OF BACKGROUND DATA: The prevalence of neither NMSCCC nor CSM is known and there exists no commonly accepted quantitative MRI definition of cervical cord compression. METHODS: A group of 183 randomly recruited volunteers, 93 women, median age 66 years, range 40-80 years, underwent MRI examination of the cervical spine and spinal cord on a 1.5 T device using conventional sequences from disc levels C2/C3 to C6/C7. The imaging criterion for cervical cord compression was defined as a change in spinal cord contour at the level of an intervertebral disc on axial or sagittal MRI scan. RESULTS: MRI signs of cervical cord compression were found in 108 individuals (59.0%; 95% CI: 51.5%-66.2%); their numbers increased with age from 31.6% in the fifth decade to 66.8% in the eighth. Clinical signs of symptomatic CSM were found in two cases (1.1%), and 75 cases (41.0%) were without compression. An anteroposterior cervical canal diameter at the level of intervertebral disc (CDdisc) of less than 9.9 mm was associated with the highest probability of NMSCCC-odds ratio (OR) = 32.5, followed by a compression ratio of ≤0.5: OR = 11.1. CONCLUSION: The prevalence of NMSCCC in a population older than 40 years is higher than previously reported and increases with age. CDdisc and compression ratio had the highest capacity to discriminate between subjects with and without asymptomatic compression, and their cut-off values could be used to objectify criteria for cervical cord compression. LEVEL OF EVIDENCE: 2.

Zobrazit více v PubMed

Al-Mefty O, Harkey HL, Marawi I, et al. Experimental chronic compressive cervical myelopathy. J Neurosurg 1993; 79:550–561.

Harkey HL, Al-Mefty O, Marawi I, et al. Experimental chronic compressive cervical myelopathy: effects of decompression. J Neurosurg 1995; 83:336–341.

Kim P, Haisa T, Kawamoto T, et al. Delayed myelopathy induced by chronic compression in the rat spinal cord. Ann Neurol 2004; 55:503–511.

Kovalova I, Bednarik J, Kerkovsky M, et al. Asymptomatic spondylotic cervical cord compression. Cesk Slov Neurol N 2015; 78/111:24–33.

Bednarik J, Kadanka Z, Dusek L, et al. Pre-symptomatic spondylotic cervical cord compression. Spine (Phila Pa 1976) 2004; 29:2260–2269.

Bednarik J, Kadanka Z, Dusek L, et al. Presymptomatic spondylotic cervical myelopathy—an updated predictive model. Eur Spine J 2008; 17:421–431.

Teresi LM, Lufkin RB, Reicher MA, et al. Asymptomatic degenerative disc disease and spondylosis of the cervical spine: MR imaging. Radiology 1987; 164:83–88.

Baptiste DC, Fehlings MG. Pathophysiology of cervical myelopathy. Spine J 2006; 6 (suppl 6):190–197.

Daniel WW. Biostatistics: A Foundation for Analysis in the Health Sciences. 7th edNew York: John Wiley & Sons; 1999.

Shimomura T, Sumi M, Nishida K, et al. Prognostic factors for deterioration of patients with cervical spondylotic myelopathy after nonsurgical treatment. Spine (Phila Pa 1976) 2007; 32:2474–2479.

Kameyama T, Hashizume Y, Ando T, et al. Spinal cord morphology and pathology in ossification of the posterior longitudinal ligament. Brain 1995; 118:263–278.

Lee S-H, Kim K-T, Suk K-S, et al. Asymptomatic cervical cord compression in lumbar spinal stenosis patients. A whole spine magnetic resonance imaging study. Spine (Phila Pa 1976) 2010; 35:2057–2063.

Kadaňka Z, Keřkovský M, Bednařík J, et al. Cross-sectional transverse area and hyperintensities on MRI in relation to the clinical picture in cervical spondylotic myelopathy. Spine (Phila Pa 1976) 2007; 32:2573–2577.

Kerkovsky M, Bednarik J, Dusek L, et al. Magnetic resonance diffusion tensor imaging in patients with cervical spondylotic spinal cord compression: correlations between clinical and electrophysiological findings. Spine (Phila Pa 1976) 2012; 37:48–56.

Nejnovějších 20 citací...

Zobrazit více v
Medvik | PubMed

Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy

. 2024 ; 15 () : 1341371. [epub] 20240510

Quantitative MR Markers in Non-Myelopathic Spinal Cord Compression: A Narrative Review

. 2022 Apr 20 ; 11 (9) : . [epub] 20220420

Semi-automated detection of cervical spinal cord compression with the Spinal Cord Toolbox

. 2022 Apr ; 12 (4) : 2261-2279.

Degenerative Cervical Myelopathy: Development and Natural History [AO Spine RECODE-DCM Research Priority Number 2]

. 2022 Feb ; 12 (1_suppl) : 39S-54S.

A New Framework for Investigating the Biological Basis of Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: Mechanical Stress, Vulnerability and Time

. 2022 Feb ; 12 (1_suppl) : 78S-96S.

In vivo Molecular Signatures of Cervical Spinal Cord Pathology in Degenerative Compression

. 2021 Nov 01 ; 38 (21) : 2999-3010.

Diffusion magnetic resonance imaging reveals tract-specific microstructural correlates of electrophysiological impairments in non-myelopathic and myelopathic spinal cord compression

. 2021 Nov ; 28 (11) : 3784-3797. [epub] 20210804

Walk and Run Test in Patients with Degenerative Compression of the Cervical Spinal Cord

. 2021 Mar 01 ; 10 (5) : . [epub] 20210301

HARDI-ZOOMit protocol improves specificity to microstructural changes in presymptomatic myelopathy

. 2020 Oct 16 ; 10 (1) : 17529. [epub] 20201016

Predictors of symptomatic myelopathy in degenerative cervical spinal cord compression

. 2017 Sep ; 7 (9) : e00797. [epub] 20170811

Najít záznam

Citační ukazatele

Nahrávání dat ...

Možnosti archivace

Nahrávání dat ...