Impact of Air Pollution on the Health of the Population in Parts of the Czech Republic
Jazyk angličtina Země Švýcarsko Médium electronic
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
PubMed
32899757
PubMed Central
PMC7558327
DOI
10.3390/ijerph17186454
PII: ijerph17186454
Knihovny.cz E-zdroje
- Klíčová slova
- DNA adducts, PAHs, PM2.5, SO2, air pollution, mortality, neurobehavioral changes, pregnancy outcome, sperm abnormalities,
- MeSH
- látky znečišťující vzduch * analýza MeSH
- lidé MeSH
- pevné částice analýza MeSH
- předškolní dítě MeSH
- těhotenství MeSH
- zdraví MeSH
- znečištění ovzduší * analýza MeSH
- Check Tag
- lidé MeSH
- předškolní dítě MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Geografické názvy
- Česká republika MeSH
- Evropa MeSH
- Názvy látek
- látky znečišťující vzduch * MeSH
- pevné částice MeSH
Thirty years ago, Northern Bohemia in the Czech Republic was one of the most air polluted areas in Europe. After political changes, the Czech government put forward a research program to determine if air pollution is really affecting human health. This program, later called the "Teplice Program", was initiated in collaboration with scientists from the United States Environmental Protection Agency (US EPA). This cooperation made possible the use of methods on the contemporary level. The very high concentrations of sulphur dioxide (SO2), particulate matter of 10 micrometers or less (PM10), and polycyclic aromatic hydrocarbons (PAHs) present in the air showed, for the first time, the impact of air pollutants on the health of the population in mining districts: adverse pregnancy outcomes, the impact of air pollution on sperm morphology, learning disabilities in children, and respiratory morbidity in preschool children. A surprising result came from the distribution of the sources of pollution: 70% of PM10 pollution came from local heating and not from power plants as expected. Thanks to this result, the Czech government supported changes in local heating from brown coal to natural gas. This change substantially decreased SO2 and PM10 pollution and affected mortality, especially cardiovascular mortality.
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Skorkovsky J., Kotesovec F. Comparison of mortality in the industrial region of Northern Bohemia in the period of higher and lower level of air pollution. Air. Pollut. Prot. 2005;18:32–37. (In Czech)
Kotesovec F., Skorkovsky J., Brynda J., Peters A., Heinrich J. Daily mortality and air pollution in Northern Bohemia: Different affects for men and women. Cent. Eur. J. Public Health. 2000;8:120–127. PubMed
Sram R.J. New ethical problems related to environmental pollution. In: Sram R.J., Bulyzhenkov V., Prilipko L., Christen Y., editors. Ethical Issues of Molecular Genetics in Psychiatry. Springer; Berlin/Heidelberg, Germany: 1991. pp. 94–105.
Czech Statistical Office 2018. [(accessed on 17 April 2019)]; Available online: http://www.czso.cz.
Sram R.J., BeneS I., Binková B., Dejmek J., Horstman D., Kotĕsovec F., Skalík I. Teplice Program—The impact of air pollution on human health. Environ. Health Perspect. 1996;104:699–714. PubMed PMC
Benes I., Skorkovsky J., Novak J., Sram R.J. The development of air pollution in Teplice, Prachatice and Prague in the last thirteen years. Air Pollut. Prot. 2007;20:9–10. (In Czech)
CHMI (Czech Hydrometeorology Institute) 2018. [(accessed on 18 June 2019)]; Available online: http://portal.chmi.cz/files/portal/docs/uoco/isko/tab_roc/2018_enh/pollution_my/CZTOS_BaP_CZ.html.
Pinto J.P., Stevens R.K., Willis R.D., Kellog R., Mammane Y., Novak J., Šantroch J., Beneš I., Leniček J., Bureš V. Czech air quality monitoring and receptor modelling study. Environ. Sci. Technol. 1998;32:843–854. doi: 10.1021/es970174p. DOI
Pinto J.P., Stevens R.K., Willis R.D., Mamane Y., Ramadan Z., Hopke P.K. Source-receptor relations in Teplice and Prachatice. In: Sram R.J., editor. Teplice Program—Impact of Air Pollution on Human Health. Academia; Prague, Czech Republic: 2001. pp. 71–80.
Binková B., Leníček J., Beneš I., Vidová P., Gajdoš O., Fried M., Šrám R.J. Genotoxicity of coke-oven and urban air particulate matter in in vitro acellular assays coupled with 32P-postlabeling and HPLC analysis of DNA adducts. Mutat. Res. 1998;414:77–94. doi: 10.1016/S1383-5718(98)00040-0. PubMed DOI
Binkova B., Vesely D., Vesela D., Jelinek R., Sram R.J. Genotoxicity and embryotoxicity of urban air particulate matter collected during winter and summer period in two different districts of the Czech Republic. Mutat. Res. 1999;440:45–58. doi: 10.1016/S1383-5718(99)00011-X. PubMed DOI
De Marini D.M., Shelton M.L., Bell D.A. Mutation spectra in Salmonella of complex mixtures: Comparison of urban air to benzo[a]pyrene. Environ. Mol. Mutagen. 1994;24:262–275. doi: 10.1002/em.2850240403. PubMed DOI
De Marini D.M. Mutation spectra of complex mixtures. Mutat. Res. 1998;411:77–94. PubMed
Binkova B., Lewtas J., Miskova I., Lenicek J., Sram R. DNA adducts and personal air monitoring of carcinogenic polycyclic aromatic hydrocarbons in an environmentally exposed population. Carcinogenesis. 1995;16:1037–1046. doi: 10.1093/carcin/16.5.1037. PubMed DOI
Watts R., Lewtas J., Stevens R., Hartlage T., Pinto J., Williams R., Šrám R. Czech-US EPA health study: Assessment of personal and ambient air exposures to PAH and organic mutagens in the Teplice district of Northern Bohemia. Int. J. Environ. Anal. Chem. 1994;56:271–287. doi: 10.1080/03067319408034107. DOI
Dejmek J., Selevan S.G., Benes I., Solansky I., Sram R.J. Fetal growth and maternal exposure to particulate matter during pregnancy. Environ. Health Perspect. 1999;107:475–480. doi: 10.1289/ehp.99107475. PubMed DOI PMC
Topinka J., Binkova B., Mračková G., Stavkova Z., Beneš I., Dejmek J., Šrám R.J. DNA adducts in human placenta as related to air pollution and to GSTM1 genotype. Mutat. Res. 1997;390:59–68. doi: 10.1016/S0165-1218(96)00166-8. PubMed DOI
Dejmek J., Solansky I., Benes I., Lenicek J., Sram R.J. The impact of polycyclic aromatic hydrocarbons and fine particles on pregnancy outcome. Environ. Health Perspect. 2000;108:1159–1164. doi: 10.1289/ehp.001081159. PubMed DOI PMC
Huel G., Girard F., Nessmann C., Godin J., Blot P., Bréart G., Moreau T. Placental aryl hydrocarbon hydroxylase activity and placental calcification. Toxicology. 1992;71:257–266. doi: 10.1016/0300-483X(92)90028-D. PubMed DOI
Huel G., Godin J., Frery N., Girard F., Moreau T., Nessmann C., Blot P. Aryl hydrocarbon hydroxylase activity in human placenta and threatened preterm delivery. J. Expo. Anal. Environ. Epidemiol. 1993;3:187–189. PubMed
Hatch M.C., Warburton D., Santella R.M. Polycyclic aromatic hydrocarbon-DNA adducts in spontaneously aborted fetal tissue. Carcinogenesis. 1990;11:1673–1775. doi: 10.1093/carcin/11.9.1673. PubMed DOI
Madhavan N.D., Najdu K. Polycyclic aromatic hydrocarbons in placenta, maternal blood, umbilical cord blood and milk of Indian women. Hum. Exp. Toxicol. 1995;14:503–506. doi: 10.1177/096032719501400607. PubMed DOI
Arnould J.P., Verhoest P., Bach V., Libert J.P., Belegaud J. Detection of benzo[a]pyrene—DNA adducts in human placenta and umbilical cord blood. Hum. Exp. Toxicol. 1997;16:716–721. doi: 10.1177/096032719701601204. PubMed DOI
Guyda H.J. Metabolic effects of growth factors and polycyclic aromatic hydrocarbons on cultured human placental cells of early and late gestation. J. Clin. Endocrinol. Metab. 1991;72:718–723. doi: 10.1210/jcem-72-3-718. PubMed DOI
Zhang I., Connor E.E., Chegini N., Shiverick K.T. Modulation by benzo[a]pyrene of epidermal growth factor receptors, cell proliferation, and secretion of human chorionic gonadotropin in human placental lines. Biochem. Pharmacol. 1995;50:1171–1180. PubMed
Barker D.J. Adult consequences of fetal growth restriction. Clin. Obs. Gynecol. 2006;49:270–283. doi: 10.1097/00003081-200606000-00009. PubMed DOI
Epstein H., Dejmek J., Subrt P., Vitnerova N., Sram R.J. Trace metals and pregnancy outcome in the Czech Republic. Environ. Epidemiol. Toxicol. 2000;2:13–19.
Šrám R.J., Binková B., Rössner P., Rubeš J., Topinka J., Dejmek J. Adverse reproductive outcomes from exposure to environmental mutagens. Mutat. Res. 1999;428:203–215. doi: 10.1016/S1383-5742(99)00048-4. PubMed DOI
Rubes J., Selevan S.G., Evenson D.P., Zudova D., Vozdova M., Zudova Z., Perreault S.D. Episodic air pollution is associated with increased DNA fragmentation in human sperm without other changes in semen quality. Hum. Reprod. 2005;20:2776–2783. doi: 10.1093/humrep/dei122. PubMed DOI
Selevan S.G., Borkovec L., Slott V.L., Zudová Z., Rubes J., Evenson D.P., Perreault S.D. Semen quality and reproductive health of young Czech men exposed to seasonal air pollution. Environ. Health Perspect. 2000;108:887–894. doi: 10.1289/ehp.00108887. PubMed DOI PMC
Rubes J., Rybar R., Prinosilova P., Veznik Z., Chvatalova I., Solansky I., Sram R.J. Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution. Mutat. Res. 2010;683:9–15. doi: 10.1016/j.mrfmmm.2009.09.010. PubMed DOI
Choi H., Harrison R., Komulainen H., Delgado Saborit J.M. WHO Guidelines for Indoor Air Quality. Selected Pollutants. World Health Organization Europe, WHO Regional Office for Europe; Copenhagen, Denmark: 2010. Polycyclic aromatic hydrocarbons; pp. 289–345.
Gebhart J.A., Dytrych Z., Tyl J., Sram R.J. On the incidence of minimal brain dysfunction syndrome in children. Ceskoslov. Psychiat. 1990;86:1–6. (In Czech) PubMed
Singh J. Neonatal development altered by maternal sulphur dioxide exposure. Neurotoxicology. 1989;10:523–527. PubMed
Otto D., Skalik I., Kenneth Hudnell H., House D., Sram R.J. Neurobehavioral effects of exposure to environmental pollutants in Czech children. In: Sram R.J., editor. Teplice Program—Impact of Air Pollution on Human Health. Academia; Prague, Czech Republic: 2001. pp. 217–242.
Baker E., Letz R., Fidler A., Shalat S., Plantamura D., Lyndon M. A computer-based neurobehavioral evaluation system for occupational and environmental epidemiology: Methodology and validation studies. Neurotoxicol. Teratol. 1985;7:369–377. PubMed
Perera F.P., Rauh V., Whyatt R.M., Tsai W.Y., Tang D., Diaz D., Kinney P. Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first 3 years of life among inner/city children. Env. Health Perspect. 2006;114:1287–1292. doi: 10.1289/ehp.9084. PubMed DOI PMC
Perera F.P., Li Z., Whyatt R., Hoepner L., Wang S., Camann D., Rauh V. Prenatal airborne polycyclic aromatic hydrocarbon exposure and child IQ at age 5 years. Pediatrics. 2009;124:e195–e202. doi: 10.1542/peds.2008-3506. PubMed DOI PMC
Perera F.P., Tang D., Wang S., Vishnevetsky J., Zhang B., Diaz D., Rauh V. Prenatal polycyclic aromatic hydrocarbon (PAH) exposure and child behavior at age 6–7 years. Environ. Health Perspect. 2012;120:921–926. doi: 10.1289/ehp.1104315. PubMed DOI PMC
Peterson B.S., Rauh V.A., Bansal R., Hao X., Toth Z., Nati G., Perera F. Effects of prenatal exposure to air pollutants (polycyclic aromatic hydrocarbons) on development of brain white matter, cognition, and behavior in later childhood. JAMA Psychiatry. 2015;72:531–540. doi: 10.1001/jamapsychiatry.2015.57. PubMed DOI PMC
Edwards S.C., Jedrychowski W., Butscher M., Camann D., Kieltyka A., Mroz E., Perera F. Prenatal exposure to airborne polycyclic aromatic hydrocarbons and children intelligence at 5 years of age in a prospective cohort study in Poland. Environ. Health Perspect. 2010;118:1326–1331. doi: 10.1289/ehp.0901070. PubMed DOI PMC
Jedrychowski W.A., Perera F.P., Camann D., Spengler J., Butscher M., Mroz E., Sowa A. Prenatal exposure to polycyclic aromatic hydrocarbons and cognitive dysfunction in children. Environ. Sci. Pollut. Res. 2015;22:3631–3639. doi: 10.1007/s11356-014-3627-8. PubMed DOI PMC
Perera F., Li T.Y., Zhou Z.J., Yuan T., Chen Y.H., Qu L., Tang D. Benefits of reducing prenatal exposure to coal-burning pollutants to children’s neurodevelopment in China. Environ. Health Perspect. 2008;116:1396–1400. doi: 10.1289/ehp.11480. PubMed DOI PMC
WHO Statistical Information System, Czech Republic. [(accessed on 26 August 2020)]; Available online: http://www.who.int/countries/cze/en.
Cífková R., Škodová Z., Bruthans J., Adámková V., Jozífová M., Galovcová M., Lánská V. Longitudinal trends in major cardiovascular risk factors in the Czech population between 1985 and 2007/8. Czech MONICA and Czech post MONICA. Atherosclerosis. 2010;211:676–681. doi: 10.1016/j.atherosclerosis.2010.04.007. PubMed DOI
Fihel A., Pechholdova M. Between ‘pioneers’ of the cardiovascular revolution and its ‘late followers’: Mortality changes in the Czech Republic and Poland since 1968. Eur. J. Popul. 2017;33:651–678. doi: 10.1007/s10680-017-9456-y. PubMed DOI PMC
Mackenbach J.P., Karanikolos M., Beral J.M., Mckee M. Why did life expectancy in Central and Eastern Europe suddenly improve in the 1990s? An analysis by cause of death. Scand. J. Public Health. 2015;43:796–801. doi: 10.1177/1403494815599126. PubMed DOI
Kotesovec F., Skorkovsky J. Comparison of mortality in North-Western Bohemia in two periods of high and low air pollution. Air. Pollut. Prot. 2007;20:19–23. (In Czech)
Dejmek J., Solansky I., Podrazilova K., Sram R.J. The exposure of non-smoking and smoking mothers to environmental tobacco smoke during different gestational phases and fetal growth. Environ. Health Perspect. 2002;110:601–606. doi: 10.1289/ehp.02110601. PubMed DOI PMC
Sram R.J., Binkova B., Dostal M., Merkerova-Dostalova M., Libalova H., Milcova A., Topinka J. Health impact of air pollution to children. Int. J. Hyg. Environ. Health. 2013;216:533–540. doi: 10.1016/j.ijheh.2012.12.001. PubMed DOI
Rossnerova A., Tulupova E., Tabashidze N., Schmuczerova J., Dostal M., Rossner P., Jr., Sram R.J. Factors affecting 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments. Mutat. Res. 2013;741–742:18–26. doi: 10.1016/j.mrfmmm.2013.02.003. PubMed DOI
Sram R.J., Rössner P., Jr., Rössnerová A., Dostál M., Milcová A., Svecová V., Velemínský M., Jr. Impact of air pollution to genome of newborns: ISEE Conference Abstracts. [(accessed on 15 June 2020)];Cent. Eur. J. Public Health. 2016 2016:S40–S44. doi: 10.21101/cejph.a4536. Available online: https://ehp.niehs.nih.gov/doi/10.1289/isee.2016.4303. PubMed DOI
Ambroz A., Vlkova V., Rossner P., Jr., Rossnerova A., Svecova V., Milcova A., Sram R.J. Impact of air pollution on oxidative DNA damage and lipid peroxidation in mothers and their newborns. Int. J. Hyg. Env. Health. 2016;219:545–556. doi: 10.1016/j.ijheh.2016.05.010. PubMed DOI
Honkova K., Rossnerova A., Pavlikova J., Svecova V., Klema J., Topinka J., Sram R.J. Gene expression profiling in healthy newborns from diverse localities of the Czech Republic. Environ. Mol. Mutagen. 2018;59:401–415. doi: 10.1002/em.22184. PubMed DOI
Urbancova K., Lankova D., Rossner P., Rossnerova A., Svecova V., Tomaniova M., Pulkrabova J. Evaluation of 11 polycyclic aromatic hydrocarbon metabolites in urine of Czech moths and newborns. Sci. Total Environ. 2017;577:212–219. doi: 10.1016/j.scitotenv.2016.10.165. PubMed DOI