Brucella microti and Rodent-Borne Brucellosis: A Neglected Public Health Threat
Language English Country Germany Media print-electronic
Document type Journal Article, Review, Research Support, Non-U.S. Gov't
Grant support
Ministerstvo Zdravotnictví Ceské Republiky
PubMed
39439057
PubMed Central
PMC11695703
DOI
10.1111/zph.13188
Knihovny.cz E-resources
- Keywords
- Brucella, public health risk, rodent, sapronosis, zoonosis,
- MeSH
- Brucella * isolation & purification MeSH
- Brucellosis * epidemiology veterinary microbiology transmission MeSH
- Rodentia * microbiology MeSH
- Humans MeSH
- Public Health * MeSH
- Zoonoses * MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Brucellosis is one of the most important zoonoses worldwide, primarily affecting livestock but also posing a serious threat to public health. The major Brucella species are known to cause a feverish disease in humans with various clinical signs. These classical Brucella species are (re-)emerging, but also novel strains and species, some of them transmitted from rodents, can be associated with human infections. As a result of our review on rodent-borne brucellosis, we emphasise the need for more comprehensive surveillance of Brucella and especially Brucella microti in rodent populations and call for further research targeting the ecological persistence of rodent-associated Brucella species in the environment, their epizootic role in wild rodents and their virulence and pathogenicity for wildlife.
Department 1 Infectious Diseases Robert Koch Institute Berlin Germany
Department of Bacteriology Animal and Plant Health Agency Weybridge UK
Department of Experimental Biology Masaryk University Brno Czech Republic
Institute of Vertebrate Biology Czech Academy of Sciences Brno Czech Republic
See more in PubMed
About, F. , Pastre T., Boutru M., et al. 2023. “Novel Species of Brucella Causing Human Brucellosis, French Guiana.” Emerging Infectious Diseases 29: 333–340. 10.3201/eid2902.220725. PubMed DOI PMC
Ackelsberg, J. , Liddicoat A., Burke T., et al. 2020. “ Brucella Exposure Risk Events in 10 Clinical Laboratories, New York City, USA, 2015 to 2017.” Journal of Clinical Microbiology 58: e01096‐219‐2019. 10.1128/JCM.01096-19. PubMed DOI PMC
Al Dahouk, S. , Hofer E., Tomaso H, et al. 2012. “Intraspecies Biodiversity of the Genetically Homologous Species Brucella microti .” Applied and Environmental Microbiology 78: 1534–1543. 10.1128/AEM.06351-11. PubMed DOI PMC
Al Dahouk, S. , Köhler S., Occhialini A., et al. 2017. “ Brucella spp. of Amphibians Comprise Genomically Diverse Motile Strains Competent for Replication in Macrophages and Survival in Mammalian Hosts.” Scientific Reports 7: 44420. 10.1038/srep44420. PubMed DOI PMC
Audic, S. , Lescot M., Claverie J. M., and Scholz H. C.. 2009. “ Brucella microti: The Genome Sequence of an Emerging Pathogen.” BMC Genomics 10: 352. 10.1186/1471-2164-10-352. PubMed DOI PMC
Bai, Y. , Urushadze L., Osikowicz L., et al. 2017. “Molecular Survey of Bacterial Zoonotic Agents in Bats From the Country of Georgia (Caucasus).” PLoS One 12: e0171175. 10.1371/journal.pone.0171175. PubMed DOI PMC
Beal, G. A. , Lewis R. E., McCullough N. B., and Claflin R. M.. 1959. “Experimental Infection of Swine With Brucella neotomae .” American Journal of Veterinary Research 20: 872–875. PubMed
Boeer, W. J. , Crawford R. P., Hidalgo R. J., and Robinson R. M.. 1980. “Small Mammals and White‐Tailed Deer as Possible Reservoir Hosts of Brucella abortus in Texas.” Journal of Wildlife Diseases 16, no. 1: 19–24. 10.7589/0090-3558-16.1.19. PubMed DOI
Brangsch, H. , Horstkotte M. A., and Melzer F.. 2023. “Genotypic Peculiarities of a Human Brucellosis Case Caused by Brucella suis Biovar 5.” Scientific Reports 13, no. 1: 16586. 10.1038/s41598-023-43570-4. PubMed DOI PMC
Cameron, H. S. , and Meyer M. E.. 1958. “Metabolic Studies on Brucella neotomae (Stoenner and Lackman).” Journal of Bacteriolology 76: 546–548. 10.1128/jb.76.5.546-548.1958. PubMed DOI PMC
Chakma, S. , Picard J., Duffy R., Constantinoiu C., and Gummow B.. 2017. “A Survey of Zoonotic Pathogens Carried by Non‐Indigenous Rodents at the Interface of the Wet Tropics of North Queensland, Australia.” Transboundary and Emerging Diseases 64: 185–64193. 10.1111/tbed.12360. PubMed DOI
Cook, I. , Campbell R. W., and Barrow G.. 1966. “Brucellosis in North Queensland Rodents.” Australian Veterinary Journal 42: 5–8. 10.1111/j.1751-0813.1966.tb04603.x. PubMed DOI
Corbel, M. J. 1984. “International Committee on Systematic Bacteriology Subcommittee on Taxonomy of Brucella .” International Journal of Systematic and Evolutionary Microbiology 34, no. 3: 366–367. 10.1099/00207713-34-3-366. PubMed DOI
Damiano, M. A. , Bastianelli D., Al Dahouk S., et al. 2015. “Glutamate Decarboxylase‐Dependent Acid Resistance in Brucella spp.: Distribution and Contribution to Fitness Under Extremely Acidic Conditions.” Applied and Environmental Microbiology 81: 578–586. 10.1128/AEM.02928-14. PubMed DOI PMC
De, B. K. , Stauffer L., Koylass M. S., et al. 2008. “Novel Brucella Strain (BO1) Associated With a Prosthetic Breast Implant Infection.” Journal of Clinical Microbiology 46: 43–49. 10.1128/JCM.01494-07. PubMed DOI PMC
Dranovskaia, E. A. , Malikov V. E., and Grekova N. A.. 1983. “Izuchenie Biologicheskikh i Fiziko‐Khimicheskikh svoĭstv Brutsell, Vydelennykh Ot Myshevidnykh Gryzunov [Biological and Physicochemical Properties of Brucella Isolated From Murine Rodents].” [In Russian.] Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii 1: 47–53. PubMed
Dushina, O. P. , Mitrofanova L. I., Chudentsova E. N., and Savchenko N. T.. 1964. “A Case of Isolation of Atypical Brucella From Murine Rodents in the Chechen‐Ingush Autonomic Republic.” [In Russian.] Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii 41: 143–144. PubMed
Eisenberg, T. , Hamann H. P., Kaim U., et al. 2012. “Isolation of Potentially Novel Brucella spp. From Frogs.” Applied and Environmental Microbiology 78: 3753–3755. 10.1128/AEM.07509-11. PubMed DOI PMC
Eisenberg, T. , Riße K., Schauerte N., Geiger C., Blom J., and Scholz H. C.. 2017. “Isolation of a Novel 'Atypical' Brucella Strain From a Bluespotted Ribbontail Ray (Taeniura lymma).” Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiolgy 110: 221–234. 10.1007/s10482-016-0792-4. PubMed DOI
Eisenberg, T. , Schlez K., Fawzy A., et al. 2020. “Expanding the Host Range: Infection of a Reptilian Host (Furcifer pardalis) by an Atypical Brucella Strain.” Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology 113: 1531–1537. 10.1007/s10482-020-01448-9. PubMed DOI PMC
El‐Sayed, A. , and Awad W.. 2018. “Brucellosis: Evolution and Expected Comeback.” International Journal of Veterinary Science and Medicine 6: 31–35. 10.1016/j.ijvsm.2018.01.008. PubMed DOI PMC
European Centre for Disease Prevention and Control . 2023. “Brucellosis.” In ECDC. Annual Epidemiological Report for 2021. Stockholm: ECDC.
Fischer, D. , Lorenz N., Heuser W., Kämpfer P., Scholz H. C., and Lierz M.. 2012. “Abscesses Associated With Brucella inopinata‐Like Bacterium in Big‐Eyed Tree Frog (Leptopelis Vermiculatus).” Journal of Zoo and Wildlife Medicine 43: 625–628. 10.1638/2011-0005R2.1. PubMed DOI
Foster, G. , Osterman B. S., Godfroid J. I., and Cloeckaert A.. 2007. “ Brucella ceti sp. nov. and Brucella pinnipedialis sp. nov. for Brucella Strains With Cetaceans and Seals as Their Preferred Hosts.” International Journal of Systematic and Evolutionary Microbiology 57: 2688–2693. 10.1099/ijs.0.65269-0. PubMed DOI
Gibby, I. W. , and Gibby A. M.. 1965. “Host‐Parasite Relationships With Brucella neotomae .” Journal of Bacteriolology 89: 9–16. 10.1128/jb.89.1.9-16.1965. PubMed DOI PMC
González‐Espinoza, G. , Arce‐Gorvel V., Mémet S., and Gorvel J. P.. 2021. “ Brucella: Reservoirs and Niches in Animals and Humans.” Pathogens 10: 186. 10.3390/pathogens10020186. PubMed DOI PMC
Guzmán‐Verri, C. , Suárez‐Esquivel M., Ruíz‐Villalobos N., et al. 2019. “Genetic and Phenotypic Characterization of the Etiological Agent of Canine Orchiepididymitis Smooth Brucella sp. BCCN84.3.” Frontiers in Veterinary Science 6: 175. 10.3389/fvets.2019.00175. PubMed DOI PMC
Hammerl, J. A. , Ulrich R. G., Imholt C., et al. 2017. “Molecular Survey on Brucellosis in Rodents and Shrews—Natural Reservoirs of Novel Brucella Species in Germany?” Transboundary and Emerging Diseases 64, no. 2: 663–671. 10.1111/tbed.12425. PubMed DOI
Hanna, N. , Jiménez de Bagüés M. P., Ouahrani‐Bettache S., El Yakhlifi Z., Köhler S., and Occhialini A.. 2011. “The virB Operon Is Essential for Lethality of Brucella microti in the Balb/c Murine Model of Infection.” Journal of Infectious Diseases 15: 1129–1135. 10.1093/infdis/jiq163. PubMed DOI
Heisch, R. B. , Cooke E. R., Harvey A. E., and De Souza F.. 1963. “The Isolation of Brucella suis From Rodents in Kenya.” East African Medical Journal 40: 132–133. PubMed
Hofer, E. , Revilla‐Fernández S., Al Dahouk S., et al. 2012. “A Potential Novel Brucella Species Isolated From Mandibular Lymph Nodes of Red Foxes in Austria.” Veterinary Microbiology 24: 93–99. 10.1016/j.vetmic.2011.08.009. PubMed DOI
Hördt, A. , López M. G., Meier‐Kolthoff J. P., et al. 2020. “Analysis of 1,000+ Type‐Strain Genomes Substantially Improves Taxonomic Classification of Alphaproteobacteria .” Frontiers in Microbiology 11: 468. 10.3389/fmicb.2020.00468. PubMed DOI PMC
Hubálek, Z. , Křivanová A., Nesvadbová J., and Rudolf I.. 2023. “Zoonotic Potential of Brucella microti .” Vector‐Borne and Zoonotic Diseases 23: 437–439. 10.1089/vbz.2022.0085. PubMed DOI
Hubálek, Z. , Scholz H. C., Sedláček I., Melzer F., Sanogo Y. O., and Nesvadbová J.. 2007. “Brucellosis of the Common Vole (Microtus arvalis).” Vector Borne and Zoonotic Diseases 7, no. 4: 679–687. 10.1089/vbz.2007.0143. PubMed DOI
Jaÿ, M. , Freddi L., Mick V., et al. 2020. “ Brucella microti‐Like Prevalence in French Farms Producing Frogs.” Transboundary and Emerging Diseases 67: 617–625. 10.1111/tbed.13377. PubMed DOI
Jaÿ, M. , Girault G., Perrot L., et al. 2018. “Phenotypic and Molecular Characterization of Brucella microti‐Like Bacteria From a Domestic Marsh Frog (Pelophylax ridibundus).” Frontiers in Veterinary Science 5: 283. 10.3389/fvets.2018.00283. PubMed DOI PMC
Jiménez de Bagüés, M. P. , de Martino A., Quintana J. F., Alcaraz A., and Pardo J.. 2011. “Course of Infection With the Emergent Pathogen Brucella microti in Immunocompromised Mice.” Infection and Immunity 79: 3934–3939. 10.1128/IAI.05542-11. PubMed DOI PMC
Jiménez de Bagüés, M. P. , Ouahrani‐Bettache S., Quintana J. F., et al. 2010. “The New Species Brucella microti Replicates in Macrophages and Causes Death in Murine Models of Infection.” Journal of Infectious Diseases 202: 3–10. 10.1086/653084. PubMed DOI
Kang, Y. S. , Brown D. A., and Kirby J. E.. 2019. “ Brucella neotomae Recapitulates Attributes of Zoonotic Human Disease in a Murine Infection Model.” Infection and Immunity 87: e00255‐18. 10.1128/IAI.00255-18. PubMed DOI PMC
Kang, Y. S. , and Kirby J. E.. 2017. “Promotion and Rescue of Intracellular Brucella neotomae Replication During Coinfection With Legionella pneumophila .” Infection and Immunity 85: e00991‐16. 10.1128/IAI.00991-16. PubMed DOI PMC
Kimura, M. , Une Y., Suzuki M., Park E., Imaoka K., and Morikawa S.. 2017. “Isolation of Brucella inopinata‐Like Bacteria From White's and Denny's Tree Frogs.” Vector Borne and Zoonotic Diseases 7: 297–302. 10.1089/vbz.2016.2027. PubMed DOI
Kolbabová, J. , Havlasová J., and Veleba J.. 2001. “Brucellosis.” Klinická Mikrobiologie infekční lékařství 7: 210–213. (Czech).
Liamkin, G. I. , Taran I. F., Safronova V. M., Tikhenko N. I., and Shiranovich M. P.. 1983. “Taxonomic Position and Ecology of the Causative Agent of Brucellosis Isolated From Murine Rodents in Regions of the Northern Foothills of the Greater Caucasus. II. The Ecological and Pathogenetic Characteristics of Brucella Strains Isolated From Murine Rodents.” [In Russian.] Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii 7: 31–35. PubMed
Liamkin, G. I. , Tiumentseva I. S., and Afanas'ev E. N.. 1983. “Taxonomy and Ecology of Brucellosis Pathogens Isolated From Muridae in the Northern Foothills of the Caucasus Mountains. I. Cultural and Biochemical Properties of Brucella Isolated From Muridae.” [In Russian.] Zh Zhurnal Mikrobiologii Epidemiologii Immunobiologii 6: 30–33. PubMed
Mand'áková, Z. 2024. “Brucelóza.” SZÚ. http://www.szu.cz/tema/prevence/bruceloza‐1 [online].
McDonald, W. L. , Jamaludin R., Mackereth G., et al. 2006. “Characterization of a Brucella sp. Strain as a Marine‐Mammal Type Despite Isolation From a Patient With Spinal Osteomyelitis in New Zealand.” Journal of Clinical Microbiology 44: 4363–4370. 10.1128/JCM.00680-06. PubMed DOI PMC
Meyer, M. E. 1976. “Evolution and Taxonomy in the Genus Brucella: Concepts on the Origins of the Contemporary Species.” American Journal of Veterinary Research 37, no. 2: 199–202. PubMed
Moore, C. G. , and Schnurrenberger P. R.. 1981. “A Review of Naturally Occurring Brucella abortus Infections in Wild Mammals.” Journal of the American Veterinary Medical Association 179, no. 11: 1105–1112. PubMed
Moreno, E. , Blasco J. M., Letesson J. J., Gorvel J. P., and Moriyón I.. 2022. “Pathogenicity and Its Implications in Taxonomy: The Brucella and Ochrobactrum Case.” Pathogens 11: 377. 10.3390/pathogens11030377. PubMed DOI PMC
Moreno, E. , Middlebrook E. A., Altamirano‐Silva P., et al. 2023. “If You're Not Confused, You're Not Paying Attention: Ochrobactrum Is Not Brucella .” Journal of Clinical Microbiology 61: 8. 10.1128/jcm.00438-23. PubMed DOI PMC
Morris, J. G., Jr. , and Southwick F. S.. 2010. “ Brucella, Voles, and Emerging Pathogens.” Journal of Infectious Diseases 202: 1–2. 10.1086/653085. PubMed DOI
Mühldorfer, K. , Wibbelt G., Szentiks C. A., et al. 2017. “The Role of ‘atypical’ Brucella in Amphibians: Are We Facing Novel Emerging Pathogens?” Journal of Applied Microbiology 122: 40–53. 10.1111/jam.13326. PubMed DOI
Occhialini, A. , Hofreuter D., Ufermann C. M., Al Dahouk S., and Köhler S.. 2022. “The Retrospective on Atypical Brucella Species Leads to Novel Definitions.” Microorganisms 10: 813. 10.3390/microorganisms10040813. PubMed DOI PMC
Olsen, S. C. , and Palmer M. V.. 2014. “Advancement of Knowledge of Brucella Over the Past 50 Years.” Veterinary Pathology 51: 1076–1089. 10.1177/0300985814540545. PubMed DOI
Ouahrani‐Bettache, S. , Jiménez De Bagüés M. P., De La Garza J., et al. 2019. “Lethality of Brucella Microti in a Murine Model of Infection Depends on the wbkE Gene Involved in O‐Polysaccharide Synthesis.” Virulence 10: 868–878. 10.1080/21505594.2019.1682762. PubMed DOI PMC
Pappas, G. 2010. “The Changing Brucella Ecology: Novel Reservoirs, New Threats.” International Journal of Antimicrobial Agents 36: 8–11. 10.1016/j.ijantimicag.2010.06.013. PubMed DOI
Repina, L. P. , Nikulina A. I., and Kosilov I. A.. 1993. “A Case of Human Infection With Brucellosis From a Cat.” Zhurnal Mikrobiologie Epidemiologie Immunobiologie 4: 66–68. PubMed
Rónai, Z. , Kreizinger Z., Dán Á., et al. 2015. “First Isolation and Characterization of Brucella Microti From Wild Boar.” BMC Veterinary Research 11: 147. 10.1186/s12917-015-0456-z. PubMed DOI PMC
Rouzic, N. , Desmier L., Cariou M. E., et al. 2021. “First Case of Brucellosis Caused by an Amphibian‐Type Brucella .” Clinical Infectious Diseases 72: e404–e407. 10.1093/cid/ciaa1082. PubMed DOI
Scholz, H. C. , Hubálek Z., Nesvadbová J., et al. 2008a. “Isolation of Brucella microti From Soil.” Emerging Infectious Diseases 14: 1316–1317. 10.3201/eid1408.080286. PubMed DOI PMC
Scholz, H. C. , Hubálek Z., Sedláček I., et al. 2008b. “ Brucella microti sp. nov., Isolated From the Common Vole Microtus arvalis .” International Journal of Systematic and Evolutionary Microbiology 58: 375–382. 10.1099/ijs.0.65356-0. PubMed DOI
Scholz, H. C. , Mühldorfer K., Shilton C., et al. 2016a. “The Change of a Medically Important Genus: Worldwide Occurrence of Genetically Diverse Novel Brucella Species in Exotic Frogs.” PLoS One 11: e0168872. 10.1371/journal.pone.0168872. PubMed DOI PMC
Scholz, H. C. , Nöckler K., Göllner C., et al. 2010. “ Brucella inopinata sp. nov., Isolated From a Breast Implant Infection.” International Journal of Systematic and Evolutionary Microbiology 60: 801–808. 10.1099/ijs.0.011148-0. PubMed DOI
Scholz, H. C. , Revilla‐Fernández S., Al Dahouk S., et al. 2016b. “ Brucella vulpis Sp. Nov., Isolated From Mandibular Lymph Nodes of Red Foxes (Vulpes vulpes).” International Journal of Systematic and Evolutionary Microbiology 66: 2090–2098. 10.1099/ijsem.0.000998. PubMed DOI
Sohn, A. H. , Probert W. S., Glaser C. A., et al. 2003. “Human Neurobrucellosis With Intracerebral Granuloma Caused by a Marine Mammal Brucella spp.” Emerging Infectious Diseases 9: 485–488. 10.3201/eid0904.020576. PubMed DOI PMC
Soler‐Lloréns, P. F. , Quance C. R., Lawhon S. D., et al. 2016. “A Brucella spp. Isolate From a Pac‐Man Frog (Ceratophrys ornata) Reveals Characteristics Departing From Classical Brucellae.” Frontiers in Cellular and Infection Microbiology 6: 116. 10.3389/fcimb.2016.00116. PubMed DOI PMC
Stoenner, H. G. , and Lackman D. B.. 1957. “A New Species of Brucella Isolated From the Desert Wood Rat, Neotoma lepida Thomas.” American Journal of Veterinary Research 18: 947–951. PubMed
Suárez‐Esquivel, M. , Ruiz‐Villalobos N., Jiménez‐Rojas C., et al. 2017. “ Brucella neotomae Infection in Humans, Costa Rica.” Emerging Infectious Diseases 23: 997–1000. 10.3201/eid2306.162018. PubMed DOI PMC
Tiller, R. V. , Gee J. E., Frace M. A., et al. 2010a. “Characterization of Novel Brucella Strains Originating From Wild Native Rodent Species in North Queensland, Australia.” Applied and Environmental Microbiology 76: 5837–5845. 10.1128/AEM.00620-10. PubMed DOI PMC
Tiller, R. V. , Gee J. E., Lonsway D. R., et al. 2010b. “Identification of an Unusual Brucella Strain (BO2) From a Lung Biopsy in a 52‐Year‐Old Patient With Chronic Destructive Pneumonia.” BMC Microbiology 10: 23. 10.1186/1471-2180-10-23. PubMed DOI PMC
Truong, L. Q. , Kim J. T., Yoon B. I., Her M., Jung S. C., and Hahn T. W.. 2011. “Epidemiological Survey for Brucella in Wildlife and Stray Dogs, a Cat and Rodents Captured on Farms.” Journal of Veterinary Medical Science 73: 1597–1601. 10.1292/jvms.11-0222. PubMed DOI
Vergnaud, G. , Zygmunt M. S., Ashford R. T., Whatmore A. M., and Cloeckaert A.. 2024. “Genomic Diversity and Zoonotic Potential of Brucella Neotomae .” Emerging Infectious Diseases 30, no. 1: 155–158. 10.3201/eid3001.221783. PubMed DOI PMC
Vershilova, P. A. , Liamkin G. I., Malikov V. E., Dranovskaya E. A., and Taran I. F.. 1983. “ Brucella Strains From Mouselike Rodents in Southwestern USSR.” International Journal of Systematic Bacteriology 33, no. 2: 399–400. 10.1099/00207713-33-2-399. DOI
Villalobos‐Vindas, J. M. , Amuy E., Barquero‐Calvo E., et al. 2017. “Brucellosis Caused by the Wood Rat Pathogen Brucella Neotomae: Two Case Reports.” Journal of Medical Case Reports 11, no. 1: 352. 10.1186/s13256-017-1496-8. PubMed DOI PMC
Waldrop, S. G. , and Sriranganathan N.. 2019. “Intracellular Invasion and Survival of Brucella neotomae, Another Possible Zoonotic Brucella Species.” PLoS One 14: e0213601. 10.1371/journal.pone.0213601. PubMed DOI PMC
Wattam, A. R. , Foster J. T., Mane S. P., et al. 2014. “Comparative Phylogenomics and Evolution of the Brucellae Reveal a Path to Virulence.” Journal of Bacteriology 196, no. 5: 920–930. 10.1128/jb.01091-13. PubMed DOI PMC
Wattam, A. R. , Inzana T. J., Williams K. P., et al. 2012. “Comparative Genomics of Early‐Diverging Brucella Strains Reveals a Novel Lipopolysaccharide Biosynthesis Pathway.” MBio 3, no. 5: e00246‐12. 10.1128/mBio.00246-12. PubMed DOI PMC
Whatmore, A. M. 2009. “Current Understanding of the Genetic Diversity of Brucella, an Expanding Genus of Zoonotic Pathogens.” Infection, Genetics and Evolution 9: 1168–1184. 10.1016/j.meegid.2009.07.001. PubMed DOI
Whatmore, A. M. , Davison N., Cloeckaert A., et al. 2014. “ Brucella papionis Sp. nov., Isolated From Baboons (Papio spp.).” International Journal of Systematic and Evolutionary Microbiology 64: 4120–4128. 10.1099/ijs.0.065482-0. PubMed DOI PMC
Whatmore, A. M. , Dawson C. E., Groussaud P., et al. 2008. “Marine Mammal Brucella Genotype Associated With Zoonotic Infection.” Emerging Infectious Diseases 14: 517–518. 10.3201/eid1403.070829. PubMed DOI PMC
Whatmore, A. M. , and Foster J. T.. 2021. “Emerging Diversity and Ongoing Expansion of the Genus Brucella .” Infection, Genetics and Evolution 92: 104865. 10.1016/j.meegid.2021.104865. PubMed DOI
Zhang, N. , Huang D., Wu W., et al. 2018. “Animal Brucellosis Control or Eradication Programs Worldwide: A Systematic Review of Experiences and Lessons Learned.” Preventive Veterinary Medicine 160: 105–115. 10.1016/j.prevetmed.2018.10.002. PubMed DOI
Zheng, R. , Xie S., Lu X., et al. 2018. “A Systematic Review and Meta‐Analysis of Epidemiology and Clinical Manifestations of Human Brucellosis in China.” BioMed Research International 2018: 5712920. 10.1155/2018/5712920. PubMed DOI PMC
Zygmunt, M. S. , Jacques I., Bernardet N., and Cloeckaert A.. 2012. “Lipopolysaccharide Heterogeneity in the Atypical Group of Novel Emerging Brucella Species.” Clinical and Vaccine Immunology 19, no. 9: 1370–1373. 10.1128/CVI.00300-12. PubMed DOI PMC