As part of its mission to improve the quality of care for women with gynecological cancers across Europe, the European Society of Gynecological Oncology (ESGO) organized 3 international consensus meetings with leading experts in the field to define protocols and to provide guidance for pregnant patients and healthcare providers on the management of gynecological cancers in pregnancy. Following the third consensus meeting, the guidelines published in 2019 were updated by incorporating new evidence on this field and covering new topics to provide comprehensive evidence-based guidelines on all relevant issues within a multidisciplinary setting. ESGO appointed 21 experts from relevant disciplines and 2 cancer survivors to serve on the international development group. Members of the International Network on Cancer, Infertility and Pregnancy involved in the 3 international consensus meetings were included. To ensure that the guidelines were evidence-based, data identified from a systematic search were reviewed and critically appraised. In the absence of robust scientific evidence, the guidelines were based on the consensus of the international development group. Prior to publication, the guidelines were reviewed by 100 independent international practitioners in cancer care delivery from Asia, Europe, Africa, and North and South Americas, and 3 patient representatives to ensure a global perspective. These ESGO/International Network on Cancer, Infertility and Pregnancy guidelines address all relevant aspects of imaging, pathology, surgery, medical oncology, obstetrics, radiation therapy, psychology, patient perspectives and pediatric follow-up in a multidisciplinary setting for patients with tubo-ovarian, cervical, and vulvar cancers during pregnancy. Treatment algorithms for each tumor type are also defined.

Alexandra Hospital Department of Clinical Therapeutics Athens Greece

Belfast Health and Social Care Trust Department of Pathology Belfast UK

Charles University 3 Medical Faculty Department of Obstetrics and Gynaecology Prague Czech Republic; University Hospital Kralovske Vinohrady Prague Czech Republic

Cooper University Health Care Department of Obstetrics and Gynecology Camden NJ USA

Copenhagen University Hospital Department of Pediatric Cardiology Copenhagen Denmark

ESGO ENGAGe Brussels Belgium

Fondazione Policlinico Universitario A Gemelli IRCCS Department of Women Children and Public Health Sciences Rome Italy

Institut Bergonié Bordeaux France

IRCCS Ospedale Policlinico San Martino Department of Medical Oncology Clinica di Oncologia Medica Genova Italy; University of Genova School of Medicine Department of Internal Medicine and Medical Specialties Genova Italy

Iridium Netwerk Department of Radiation Oncology Wilrijk Antwerp Belgium; University of Antwerp Faculty of Medicine and Health Sciences Wilrijk Antwerp Belgium

Karolinska Institutet Department of Medical Epidemiology and Biostatistics Stockholm Sweden

KU Leuven Department of Development and Regeneration Leuven Belgium

KU Leuven Department of Oncology Leuven Belgium

KU Leuven Department of Oncology Leuven Belgium; Netherlands Cancer Institute Department of Gynecologic Oncology Amsterdam The Netherlands

La Paz University Hospital Gynecologic Oncology Unit Madrid Spain

Medical University of Warsaw 2 Department of Obstetrics and Gynecology Warsaw Poland

Netherlands Cancer Institute Department of Gynecologic Oncology Amsterdam The Netherlands

Poissy Saint Germain Hospital Department of Gynecology and Obstetrics Poissy France; Paris Saclay University Montigny Le Bretonneux France

Polish Lymphoma Association Owl Eyes Warsaw PolandMasovian Oncology Hospital in Warsaw Warsaw Poland

Radiology Department University Hospitals Leuven Leuven Belgium; KU Leuven Department of Imaging and Pathology Translational MRI Leuven Belgium

Stichting Olijf Utrecht Netherlands

University Hospitals Leuven Department of Gynecology and Obstetrics Leuven Belgium

University of Milan Bicocca Department of Medicine and Surgery Milano Italy; Fondazione IRCCS San Gerardo dei Tintori UO Gynecology Monza Italy

University of Milan Department of Clinical Sciences and Community Health Milan Italy; Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Cà Granda Ospedale Maggiore Policlinico Milan Italy

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