Inhibitor of Growth Protein 1 [protein ING1]

topical
Terms

protein ING p33ING
protein ING-1

 

ING-1 Protein
ING1 Protein
p33ING Protein

Definition

A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.

DUI
D000076023 MeSH Browser
CUI
M000631818
Previous indexing
Tumor Suppressor Proteins (2005-2017); Intracellular Signaling Peptides and Proteins (2005-2017); Nuclear Proteins (2005-2017)
History note
2018
Public note
2018

D Chemicals and Drugs
D12.644 Peptides 1 380
D12.644.360.087 Calcineurin 76
D12.644.360.262 Cyclins 112
D12.644.360.365 I-kappa B Proteins 5
D12.644.360.410 Mesothelin 2
D12.644.360.534 Mucin-4 5
D12.644.360.539 NLR Proteins 4
D12.644.360.650 RNA-Binding Protein EWS 15
D12.776 Proteins 2 575
D12.776.476.050 Adenylyl Cyclases 160
D12.776.476.081 Axin Signaling Complex 1
D12.776.476.262 Cyclins 112
D12.776.476.338 GTP-Binding Proteins 117
D12.776.476.350 Guanylate Cyclase 29
D12.776.476.381 I-kappa B Proteins 5
D12.776.476.410 Mesothelin 2
D12.776.476.534 Mucin-4 5
D12.776.476.568 Protein-Tyrosine Kinases 620
D12.776.476.590 PTEN Phosphohydrolase 49
D12.776.476.650 RNA-Binding Protein EWS 15
D12.776.476.900 Sirtuins 20
D12.776.624 Neoplasm Proteins 411
D12.776.624.776 Tumor Suppressor Proteins 265
D12.776.624.776.021 DCC Receptor
D12.776.624.776.100 BRCA1 Protein 101
D12.776.624.776.101 BRCA2 Protein 95
D12.776.624.776.418 Cystatin M
D12.776.624.776.482 Deubiquitinating Enzyme CYLD 1
D12.776.624.776.523 Kangai-1 Protein 1
D12.776.624.776.546 Kisspeptins 6
D12.776.624.776.610 Neurofibromin 1 14
D12.776.624.776.612 Neurofibromin 2 3
D12.776.624.776.633 Patched Receptors
D12.776.624.776.654 Promyelocytic Leukemia Protein 4
D12.776.624.776.695 PTEN Phosphohydrolase 49
D12.776.624.776.745 Retinoblastoma Protein 52
D12.776.624.776.760 Smad4 Protein 7
D12.776.624.776.772 Tumor Suppressor Protein p14ARF 4
D12.776.624.776.775 Tumor Suppressor Protein p53 755
D12.776.624.776.820 Tumor Protein p73 6
D12.776.624.776.960 WT1 Proteins 29
D12.776.660 Nuclear Proteins 452
D12.776.660.075 Ataxins 2
D12.776.660.100 BRCA1 Protein 101
D12.776.660.105 BRCA2 Protein 95
D12.776.660.201 CDX2 Transcription Factor 3
D12.776.660.338 GADD45 Proteins
D12.776.660.478 Host Cell Factor C1 2
D12.776.660.502 Karyopherins 9
D12.776.660.526 Mad2 Proteins 1
D12.776.660.551 Mediator Complex 5
D12.776.660.600 NF-kappa B 215
D12.776.660.625 Antigens, Nuclear 11
D12.776.660.691 Nucleolin
D12.776.660.694 Nucleophosmin 17
D12.776.660.750 Protamines 42
D12.776.660.768 ran GTP-Binding Protein 4
D12.776.660.807 Retinoblastoma Protein 52
D12.776.660.912 Tumor Protein p73 6