Wolfram Syndrome [Wolframův syndrom]

topical
8
Terms

DIDMOAD syndrom
Wolframův syndrom 1

 

Diabetes Insipidus and Mellitus with Optic Atrophy and Deafness
Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness
DIDMOAD
DIDMOAD Syndrome
DIDMOADUD
Wolfram Syndrome 1

Persistent link   https://www.medvik.cz/link/D014929
Definition

A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.

DUI
D014929 MeSH Browser
CUI
M0022993
Previous indexing
Deafness (1966-1985); Diabetes Insipidus (1966-1985); Diabetes Mellitus, Insulin-Dependent (1984-1985); Optic Atrophy (1966-1985)
History note
86
Public note
86

Allowable subheadings

BL
blood
CF
cerebrospinal fluid
CI
chemically induced
CL
classification
CO
complications 2
DI
diagnosis 6
DG
diagnostic imaging
DH
diet therapy
DT
drug therapy 1
EC
economics
EM
embryology
EN
enzymology
EP
epidemiology
EH
ethnology
ET
etiology 2
GE
genetics 2
HI
history
IM
immunology
ME
metabolism
MI
microbiology
MO
mortality
NU
nursing
PS
parasitology
PA
pathology 1
PP
physiopathology
PC
prevention & control
PX
psychology
RT
radiotherapy
RH
rehabilitation
SU
surgery
TH
therapy 1
UR
urine
VE
veterinary
VI
virology

C Diseases
C09 Otorhinolaryngologic Diseases 680
C09.218 Ear Diseases 316
C09.218.458 Hearing Disorders 1 299
C09.218.458.341 Hearing Loss 217
C09.218.458.341.186 Deafness 436
C09.218.458.341.186.500 Deaf-Blind Disorders 65
C09.218.458.341.186.500.250 CHARGE Syndrome 1
C09.218.458.341.186.500.500 Usher Syndromes 8
C09.218.458.341.186.500.750 Wolfram Syndrome 8
C10 Nervous System Diseases 1 897
C10.292 Cranial Nerve Diseases 60
C10.292.700 Optic Nerve Diseases 120
C10.292.700.225 Optic Atrophy 51
C10.292.700.225.500 Optic Atrophies, Hereditary 5
C10.292.700.225.500.100 Optic Atrophy, Autosomal Dominant 3
C10.292.700.225.500.400 Optic Atrophy, Hereditary, Leber 24
C10.292.700.225.500.980 Wolfram Syndrome 8
C10.574 Neurodegenerative Diseases 679
C10.574.500 Heredodegenerative Disorders, Nervous System 47
C10.574.500.662 Optic Atrophies, Hereditary 5
C10.574.500.662.100 Optic Atrophy, Autosomal Dominant 3
C10.574.500.662.400 Optic Atrophy, Hereditary, Leber 24
C10.574.500.662.980 Wolfram Syndrome 8
C10.597 Neurologic Manifestations 1 055
C10.597.751 Sensation Disorders 94
C10.597.751.418 Hearing Disorders 1 299
C10.597.751.418.341 Hearing Loss 217
C10.597.751.418.341.186 Deafness 436
C10.597.751.418.341.186.500 Deaf-Blind Disorders 65
C10.597.751.418.341.186.500.250 CHARGE Syndrome 1
C10.597.751.418.341.186.500.500 Usher Syndromes 8
C10.597.751.418.341.186.500.750 Wolfram Syndrome 8
C10.597.751.941 Vision Disorders 713
C10.597.751.941.162 Blindness 429
C10.597.751.941.162.625 Deaf-Blind Disorders 65
C10.597.751.941.162.625.250 CHARGE Syndrome 1
C10.597.751.941.162.625.500 Usher Syndromes 8
C10.597.751.941.162.625.750 Wolfram Syndrome 8
C11 Eye Diseases 1 500
C11.270 Eye Diseases, Hereditary 61
C11.270.564 Optic Atrophies, Hereditary 5
C11.270.564.100 Optic Atrophy, Autosomal Dominant 3
C11.270.564.400 Optic Atrophy, Hereditary, Leber 24
C11.270.564.980 Wolfram Syndrome 8
C11.640 Optic Nerve Diseases 120
C11.640.451 Optic Atrophy 51
C11.640.451.451 Optic Atrophies, Hereditary 5
C11.640.451.451.100 Optic Atrophy, Autosomal Dominant 3
C11.640.451.451.400 Optic Atrophy, Hereditary, Leber 24
C11.640.451.451.980 Wolfram Syndrome 8
C11.966 Vision Disorders 713
C11.966.075 Blindness 429
C11.966.075.375 Deaf-Blind Disorders 65
C11.966.075.375.250 CHARGE Syndrome 1
C11.966.075.375.500 Usher Syndromes 8
C11.966.075.375.750 Wolfram Syndrome 8
C12 Urogenital Diseases 9
C12.050 Female Urogenital Diseases and Pregnancy Complications 132
C12.050.351 Female Urogenital Diseases 153
C12.050.351.968 Urologic Diseases 836
C12.050.351.968.419 Kidney Diseases 3 073
C12.050.351.968.419.135 Diabetes Insipidus 174
C12.050.351.968.419.135.500 Diabetes Insipidus, Nephrogenic 19
C12.050.351.968.419.135.750 Diabetes Insipidus, Neurogenic 23
C12.050.351.968.419.135.875 Wolfram Syndrome 8
C12.200 Male Urogenital Diseases 201
C12.200.777 Urologic Diseases 836
C12.200.777.419 Kidney Diseases 3 073
C12.200.777.419.135 Diabetes Insipidus 174
C12.200.777.419.135.500 Diabetes Insipidus, Nephrogenic 19
C12.200.777.419.135.750 Diabetes Insipidus, Neurogenic 23
C12.200.777.419.135.875 Wolfram Syndrome 8
C12.950 Urologic Diseases 836
C12.950.419 Kidney Diseases 3 073
C12.950.419.135 Diabetes Insipidus 174
C12.950.419.135.500 Diabetes Insipidus, Nephrogenic 19
C12.950.419.135.750 Diabetes Insipidus, Neurogenic 23
C12.950.419.135.875 Wolfram Syndrome 8
C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities 439
C16.131 Congenital Abnormalities 1 757
C16.131.077 Abnormalities, Multiple 332
C16.131.077.299 Deaf-Blind Disorders 65
C16.131.077.299.250 CHARGE Syndrome 1
C16.131.077.299.500 Usher Syndromes 8
C16.131.077.299.750 Wolfram Syndrome 8
C16.320 Genetic Diseases, Inborn 1 219
C16.320.290 Eye Diseases, Hereditary 61
C16.320.290.564 Optic Atrophies, Hereditary 5
C16.320.290.564.100 Optic Atrophy, Autosomal Dominant 3
C16.320.290.564.400 Optic Atrophy, Hereditary, Leber 24
C16.320.290.564.980 Wolfram Syndrome 8
C16.320.400 Heredodegenerative Disorders, Nervous System 47
C16.320.400.630 Optic Atrophies, Hereditary 5
C16.320.400.630.100 Optic Atrophy, Autosomal Dominant 3
C16.320.400.630.400 Optic Atrophy, Hereditary, Leber 24
C16.320.400.630.980 Wolfram Syndrome 8
C18 Nutritional and Metabolic Diseases 172
C18.452 Metabolic Diseases 1 205
C18.452.394 Glucose Metabolism Disorders 104
C18.452.394.750 Diabetes Mellitus 9 637
C18.452.394.750.124 Diabetes Mellitus, Type 1 3 038
C18.452.394.750.124.960 Wolfram Syndrome 8
C19 Endocrine System Diseases 892
C19.246 Diabetes Mellitus 9 637
C19.246.267 Diabetes Mellitus, Type 1 3 038
C19.246.267.960 Wolfram Syndrome 8
C19.700 Pituitary Diseases 126
C19.700.159 Diabetes Insipidus 174
C19.700.159.750 Diabetes Insipidus, Neurogenic 23
C19.700.159.875 Wolfram Syndrome 8

Wolfram-Like Syndrome, Autosomal Dominant Disease MeSH Browser

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