I-kappa B Proteins [proteiny I-kappa B]

topical
5
Terms

I-kappa B

 

I kappa B
I-kappa B
IkB DNA-Binding Proteins

Persistent link   https://www.medvik.cz/link/D020672
Definition

A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.

DUI
D020672 MeSH Browser
CUI
M0328543
Previous indexing
DNA-Binding Proteins (1998-1999); Proto-Oncogene Proteins (1993-1998)
History note
2006(2000)
Public note
2000; see I KAPPA B 2000-2005, I KAPPA B PROTEINS was indexed under PROTO-ONCOGENE PROTEINS 1993-1998 & DNA-BINDING PROTEINS 1998-1999

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 0
AG
agonists 0
AN
analysis 0
AI
antagonists & inhibitors 0
BI
biosynthesis 1
BL
blood 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 0
CL
classification 0
DF
deficiency 1
DE
drug effects 0
EC
economics 0
GE
genetics 2
HI
history 0
IM
immunology 0
IP
isolation & purification 0
ME
metabolism 2
PK
pharmacokinetics 0
PD
pharmacology 0
PH
physiology 0
PO
poisoning 0
RE
radiation effects 0
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 0
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 380
D12.644.360 Intracellular Signaling Peptides and Proteins 174
D12.644.360.011 Activating Transcription Factor 6 3
D12.644.360.024 Adaptor Proteins, Signal Transducing 176
D12.644.360.075 Apoptosis Regulatory Proteins 78
D12.644.360.087 Calcineurin 76
D12.644.360.138 Circadian Rhythm Signaling Peptides and Proteins 11
D12.644.360.175 Cold Shock Proteins and Peptides 3
D12.644.360.225 Cyclin-Dependent Kinase Inhibitor Proteins 42
D12.644.360.262 Cyclins 112
D12.644.360.265 Disks Large Homolog 4 Protein 1
D12.644.360.325 GTP-Binding Protein Regulators 16
D12.644.360.365 I-kappa B Proteins 5
D12.644.360.365.500 NF-KappaB Inhibitor alpha 3
D12.644.360.368 Inhibitor of Growth Protein 1
D12.644.360.372 Intracellular Calcium-Sensing Proteins 2
D12.644.360.410 Mesothelin 2
D12.644.360.420 Methyl-Accepting Chemotaxis Proteins
D12.644.360.534 Mucin-4 5
D12.644.360.537 Myristoylated Alanine-Rich C Kinase Substrate
D12.644.360.539 NLR Proteins 4
D12.644.360.543 Olfactory Marker Protein
D12.644.360.562 Phosphatidylethanolamine Binding Protein
D12.644.360.606 Protein Phosphatase Inhibitory Proteins
D12.644.360.650 RNA-Binding Protein EWS 15
D12.644.360.700 SAP90-PSD95 Associated Proteins
D12.644.360.813 Secreted Frizzled-Related Proteins
D12.644.360.925 Tuberous Sclerosis Complex 1 Protein 7
D12.644.360.938 Tuberous Sclerosis Complex 2 Protein 9
D12.644.360.950 Tumor Necrosis Factor alpha-Induced Protein 3 1
D12.644.360.963 Tumor Protein, Translationally-Controlled 1
D12.776 Proteins 2 575
D12.776.260 DNA-Binding Proteins 556
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.103 Basic Helix-Loop-Helix Transcription Factors 61
D12.776.260.108 Basic-Leucine Zipper Transcription Factors 18
D12.776.260.114 Butyrate Response Factor 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.158 Early Growth Response Transcription Factors 1
D12.776.260.197 Elongin
D12.776.260.235 Erythroid-Specific DNA-Binding Factors 1
D12.776.260.246 Factor For Inversion Stimulation Protein
D12.776.260.254 G-Box Binding Factors
D12.776.260.257 GATA Transcription Factors 2
D12.776.260.260 Heat Shock Transcription Factors 1
D12.776.260.262 Hepatocyte Nuclear Factors 5
D12.776.260.268 Heterogeneous-Nuclear Ribonucleoprotein K
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 122
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.420.500 NF-KappaB Inhibitor alpha 3
D12.776.260.457 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.260.495 Integration Host Factors
D12.776.260.504 Interferon Regulatory Factors 11
D12.776.260.513 Interferon-Stimulated Gene Factor 3
D12.776.260.522 Kruppel-Like Transcription Factors 26
D12.776.260.525 Ku Autoantigen 5
D12.776.260.527 Leucine-Responsive Regulatory Protein
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 5
D12.776.260.532 Matrix Attachment Region Binding Proteins 9
D12.776.260.534 MDS1 and EVI1 Complex Locus Protein 2
D12.776.260.536 Methyl-CpG-Binding Protein 2 12
D12.776.260.538 Minichromosome Maintenance 1 Protein 1
D12.776.260.539 MRE11 Homologue Protein 6
D12.776.260.540 MutL Proteins
D12.776.260.556 MutS Proteins
D12.776.260.560 Myeloid-Lymphoid Leukemia Protein 39
D12.776.260.600 NF-kappa B 215
D12.776.260.605 NFI Transcription Factors 6
D12.776.260.615 Nuclear Respiratory Factors
D12.776.260.623 Nucleobindins 3
D12.776.260.630 Oncogene Protein p55(v-myc) 1
D12.776.260.640 Origin Recognition Complex 1
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.645 Paired Box Transcription Factors 21
D12.776.260.650 Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
D12.776.260.655 POU Domain Factors 4
D12.776.260.660 Proto-Oncogene Proteins c-bcl-6 3
D12.776.260.665 Proto-Oncogene Proteins c-ets 19
D12.776.260.675 Proto-Oncogene Proteins c-myb 30
D12.776.260.682 Proto-Oncogene Proteins c-rel 2
D12.776.260.690 Proto-Oncogene Proteins c-sis 3
D12.776.260.693 PTB-Associated Splicing Factor
D12.776.260.695 Rad51 Recombinase 42
D12.776.260.696 Rad52 DNA Repair and Recombination Protein 9
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.733 TEA Domain Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 24
D12.776.260.750 Toll-Like Receptor 9 16
D12.776.260.755 Trans-Activators 110
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.768 Transcription Factor MTF-1
D12.776.260.775 Transcription Factors, General 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.805 Tumor Suppressor p53-Binding Protein 1 16
D12.776.260.820 Tumor Suppressor Protein p53 755
D12.776.260.885 Tumor Protein p73 6
D12.776.260.950 Winged-Helix Transcription Factors
D12.776.260.963 X-ray Repair Cross Complementing Protein 1 9
D12.776.260.975 Xeroderma Pigmentosum Group A Protein 2
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.008 3',5'-Cyclic-AMP Phosphodiesterases 12
D12.776.476.009 3',5'-Cyclic-GMP Phosphodiesterases 2
D12.776.476.011 Activating Transcription Factor 6 3
D12.776.476.024 Adaptor Proteins, Signal Transducing 176
D12.776.476.050 Adenylyl Cyclases 160
D12.776.476.075 Apoptosis Regulatory Proteins 78
D12.776.476.081 Axin Signaling Complex 1
D12.776.476.156 Circadian Rhythm Signaling Peptides and Proteins 11
D12.776.476.175 Cold Shock Proteins and Peptides 3
D12.776.476.225 Cyclin-Dependent Kinase Inhibitor Proteins 42
D12.776.476.262 Cyclins 112
D12.776.476.265 Disks Large Homolog 4 Protein 1
D12.776.476.325 GTP-Binding Protein Regulators 16
D12.776.476.338 GTP-Binding Proteins 117
D12.776.476.350 Guanylate Cyclase 29
D12.776.476.381 I-kappa B Proteins 5
D12.776.476.381.500 NF-KappaB Inhibitor alpha 3
D12.776.476.383 Inhibitor of Growth Protein 1
D12.776.476.387 Intracellular Calcium-Sensing Proteins 2
D12.776.476.410 Mesothelin 2
D12.776.476.420 Methyl-Accepting Chemotaxis Proteins
D12.776.476.445 Mitogen-Activated Protein Kinase Phosphatases 1
D12.776.476.534 Mucin-4 5
D12.776.476.539 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.476.543 Olfactory Marker Protein
D12.776.476.555 Phosphatidylethanolamine Binding Protein
D12.776.476.556 Phosphatidylinositol 3-Kinases 120
D12.776.476.557 Phosphoinositide Phospholipase C 2
D12.776.476.559 Phosphoprotein Phosphatases 23
D12.776.476.561 Protein Phosphatase Inhibitory Proteins
D12.776.476.563 Protein Serine-Threonine Kinases 271
D12.776.476.564 Protein Tyrosine Phosphatases 27
D12.776.476.568 Protein-Tyrosine Kinases 620
D12.776.476.590 PTEN Phosphohydrolase 49
D12.776.476.650 RNA-Binding Protein EWS 15
D12.776.476.700 SAP90-PSD95 Associated Proteins
D12.776.476.800 Secreted Frizzled-Related Proteins
D12.776.476.900 Sirtuins 20
D12.776.476.932 Tuberous Sclerosis Complex 1 Protein 7
D12.776.476.935 Tuberous Sclerosis Complex 2 Protein 9
D12.776.476.938 Tumor Necrosis Factor alpha-Induced Protein 3 1
D12.776.476.941 Tumor Protein, Translationally-Controlled 1
D12.776.930 Transcription Factors 727
D12.776.930.100 Adenovirus E1A Proteins 5
D12.776.930.110 Adenovirus E1B Proteins 3
D12.776.930.120 Antennapedia Homeodomain Protein 1
D12.776.930.123 AIRE Protein 2
D12.776.930.125 Basic Helix-Loop-Helix Transcription Factors 61
D12.776.930.127 Basic-Leucine Zipper Transcription Factors 18
D12.776.930.130 beta Catenin 97
D12.776.930.137 BRCA1 Protein 101
D12.776.930.146 CDX2 Transcription Factor 3
D12.776.930.155 Core Binding Factors 3
D12.776.930.160 COUP Transcription Factors
D12.776.930.165 Cyclic AMP Receptor Protein 2
D12.776.930.211 E2F Transcription Factors 16
D12.776.930.213 Early Growth Response Transcription Factors 1
D12.776.930.215 Elongin
D12.776.930.216 Erythroid-Specific DNA-Binding Factors 1
D12.776.930.312 Fushi Tarazu Transcription Factors
D12.776.930.313 G-Box Binding Factors
D12.776.930.314 GATA Transcription Factors 2
D12.776.930.315 Goosecoid Protein 2
D12.776.930.317 Heat Shock Transcription Factors 1
D12.776.930.318 Hepatocyte Nuclear Factors 5
D12.776.930.320 Homeobox Protein PITX2
D12.776.930.321 Homeobox Protein Nkx-2.2
D12.776.930.324 Homeobox Protein Nkx-2.5 1
D12.776.930.325 Host Cell Factor C1 2
D12.776.930.326 I-kappa B Proteins 5
D12.776.930.326.500 NF-KappaB Inhibitor alpha 3
D12.776.930.327 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.930.329 Inhibitor of Differentiation Proteins 2
D12.776.930.332 Interferon Regulatory Factors 11
D12.776.930.354 Interferon-Stimulated Gene Factor 3
D12.776.930.375 Kruppel-Like Transcription Factors 26
D12.776.930.386 Leucine-Responsive Regulatory Protein
D12.776.930.397 MADS Domain Proteins 3
D12.776.930.419 MDS1 and EVI1 Complex Locus Protein 2
D12.776.930.440 MSX1 Transcription Factor 8
D12.776.930.462 Myeloid Ecotropic Viral Integration Site 1 Protein 1
D12.776.930.483 Myeloid-Lymphoid Leukemia Protein 39
D12.776.930.542 Nanog Homeobox Protein 3
D12.776.930.600 NF-kappa B 215
D12.776.930.608 NFATC Transcription Factors 13
D12.776.930.612 NFI Transcription Factors 6
D12.776.930.616 Nuclear Factor 90 Proteins
D12.776.930.617 Nuclear Receptor Coactivators 6
D12.776.930.618 Nuclear Respiratory Factors
D12.776.930.640 Onecut Transcription Factors
D12.776.930.645 Orphan Nuclear Receptors 2
D12.776.930.650 Otx Transcription Factors 4
D12.776.930.680 p300-CBP Transcription Factors 5
D12.776.930.700 Paired Box Transcription Factors 21
D12.776.930.705 Peroxisome Proliferator-Activated Receptors 54
D12.776.930.710 POU Domain Factors 4
D12.776.930.712 Pre-B-Cell Leukemia Transcription Factor 1 2
D12.776.930.713 Promyelocytic Leukemia Protein 4
D12.776.930.714 B-Cell Lymphoma 3 Protein
D12.776.930.715 Proto-Oncogene Proteins c-bcl-6 3
D12.776.930.720 Proto-Oncogene Proteins c-ets 19
D12.776.930.725 Proto-Oncogene Proteins c-myb 30
D12.776.930.730 Proto-Oncogene Proteins c-rel 2
D12.776.930.760 Receptors, Aryl Hydrocarbon 133
D12.776.930.770 Receptors, Notch 20
D12.776.930.775 Receptors, Retinoic Acid 42
D12.776.930.778 Receptors, Steroid 143
D12.776.930.780 Repressor Proteins 189
D12.776.930.785 Rho Factor 12
D12.776.930.800 Sigma Factor 55
D12.776.930.806 Smad Proteins 14
D12.776.930.809 SMARCB1 Protein 15
D12.776.930.815 Snail Family Transcription Factors 4
D12.776.930.823 SOX Transcription Factors 1
D12.776.930.840 STAT Transcription Factors 23
D12.776.930.850 T-Box Domain Proteins 14
D12.776.930.875 TCF Transcription Factors 3
D12.776.930.882 TEA Domain Transcription Factors 3
D12.776.930.888 Thyroid Nuclear Factor 1
D12.776.930.900 Trans-Activators 110
D12.776.930.907 Transcription Factor AP-2 1
D12.776.930.908 Transcription Factor DP1 10
D12.776.930.919 Transcription Factor MTF-1
D12.776.930.930 Transcription Factors, General 1
D12.776.930.955 Transcriptional Elongation Factors 8
D12.776.930.960 Tristetraprolin 2
D12.776.930.969 Tumor Protein p73 6
D12.776.930.977 Winged-Helix Transcription Factors

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