Mediator Complex [mediátorový komplex]

topical
5
Terms

komplexy podobné mediátoru
proteinový komplex asociovaný s receptory thyreoidálních hormonů
transkripční mediátor
TRAP (protein asociovaný s receptory thyreoidálních hormonů)

 

Mediator Transcription Complex
Mediator-Like Complex
Mediator-Like Complexes
Thyroid Hormone-Associated Protein Complex
TR-Associated Protein (TRAP) Complex
TRAP (Thyroid Hormone Associated Protein) Complex

Persistent link   https://www.medvik.cz/link/D056892
Definition

A large protein complex which acts as a signaling adaptor protein that allows communication between the various regulatory and functional components of GENETIC TRANSCRIPTION including DNA POLYMERASE II; GENERAL TRANSCRIPTION FACTORS; and TRANSCRIPTION FACTORS that are bound to upstream ENHANCER ELEMENTS. The mediator complex was originally studied in YEAST where at least 21 subunits were identified. Many of the yeast subunits are homologs to proteins in higher organisms that are found associated with specific nuclear receptors such as THYROID HORMONE RECEPTORS and VITAMIN D RECEPTORS.

DUI
D056892 MeSH Browser
CUI
M0533184
Previous indexing
RNA Polymerase II (1994-2009); Transcription Factors (1994-2009)
History note
2010; for TRAP (THYROID HORMONE ASSOCIATED PROTEIN) COMPLEX, TR-ASSOCIATED PROTEIN (TRAP) COMPLEX and THYROID HORMONE-ASSOCIATED PROTEIN COMPLEX use MEDIATOR COMPLEX SUBUNIT 1 2003-2009
Public note
2010; TRAP (THYROID HORMONE ASSOCIATED PROTEIN) COMPLEX, TR-ASSOCIATED PROTEIN (TRAP) COMPLEX and THYROID HORMONE-ASSOCIATED PROTEIN COMPLEX were indexed under TRANSCRIPTION FACTORS 2003-2009

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 3
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 3
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D05 Macromolecular Substances 103
D05.500 Multiprotein Complexes 65
D05.500.049 Amyloid 166
D05.500.099 Apoptosomes 2
D05.500.117 Axin Signaling Complex 1
D05.500.135 Calcifying Nanoparticles 1
D05.500.139 COP9 Signalosome Complex
D05.500.142 Dynactin Complex 1
D05.500.149 Dystrophin-Associated Protein Complex 1
D05.500.199 Endosomal Sorting Complexes Required for Transport 8
D05.500.224 Inflammasomes 25
D05.500.299 Lactose Synthase
D05.500.337 Mechanistic Target of Rapamycin Complex 1 18
D05.500.356 Mechanistic Target of Rapamycin Complex 2 3
D05.500.374 Mediator Complex 5
D05.500.374.249 Cyclin C 1
D05.500.374.500 Cyclin-Dependent Kinase 8 1
D05.500.374.750 Mediator Complex Subunit 1 1
D05.500.437 Mitochondrial Permeability Transition Pore 8
D05.500.469 Mitochondrial Precursor Protein Import Complex Proteins
D05.500.500 Molecular Motor Proteins 11
D05.500.562 Multienzyme Complexes 40
D05.500.672 NF-kappa B 218
D05.500.781 Polycomb-Group Proteins 7
D05.500.890 Protein Translocation Systems
D05.500.918 Shelterin Complex 2
D05.500.945 Troponin 264
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 382
D12.644.360 Intracellular Signaling Peptides and Proteins 174
D12.644.360.024 Adaptor Proteins, Signal Transducing 176
D12.644.360.024.050 14-3-3 Proteins 75
D12.644.360.024.065 A Kinase Anchor Proteins 1
D12.644.360.024.082 Angiomotins 1
D12.644.360.024.098 Arrestins 6
D12.644.360.024.131 CARD Signaling Adaptor Proteins 7
D12.644.360.024.264 Caveolin 1 14
D12.644.360.024.272 Caveolin 2 1
D12.644.360.024.280 Cortactin 1
D12.644.360.024.282 Crk-Associated Substrate Protein 7
D12.644.360.024.285 Death Domain Receptor Signaling Adaptor Proteins 5
D12.644.360.024.287 Discs Large Homolog 1 Protein
D12.644.360.024.288 Dishevelled Proteins 18
D12.644.360.024.290 GRB2 Adaptor Protein 3
D12.644.360.024.299 GRB7 Adaptor Protein
D12.644.360.024.300 GRB10 Adaptor Protein
D12.644.360.024.301 Insulin Receptor Substrate Proteins 6
D12.644.360.024.302 Interferon Regulatory Factors 11
D12.644.360.024.303 Interferon-Stimulated Gene Factor 3
D12.644.360.024.306 Kelch-Like ECH-Associated Protein 1 9
D12.644.360.024.309 Mediator Complex 5
D12.644.360.024.309.249 Cyclin C 1
D12.644.360.024.309.750 Mediator Complex Subunit 1 1
D12.644.360.024.310 mTOR Associated Protein, LST8 Homolog
D12.644.360.024.311 Myeloid Differentiation Factor 88 16
D12.644.360.024.313 Nod Signaling Adaptor Proteins 1
D12.644.360.024.314 Nuclear Receptor Coactivators 6
D12.644.360.024.315 Nuclear Receptor Interacting Protein 1 3
D12.644.360.024.316 Paxillin 5
D12.644.360.024.318 PII Nitrogen Regulatory Proteins
D12.644.360.024.319 Protein Inhibitors of Activated STAT 3
D12.644.360.024.320 Proto-Oncogene Proteins c-crk 1
D12.644.360.024.321 Proto-Oncogene Proteins c-vav 4
D12.644.360.024.322 Rabphilin-3A
D12.644.360.024.323 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.644.360.024.324 Regulatory-Associated Protein of mTOR
D12.644.360.024.328 Retinoblastoma Binding Proteins 3
D12.644.360.024.329 Sequestosome-1 Protein 3
D12.644.360.024.330 Shc Signaling Adaptor Proteins
D12.644.360.024.332 Signaling Lymphocytic Activation Molecule Associated Protein
D12.644.360.024.334 Smad Proteins 14
D12.644.360.024.342 STAT Transcription Factors 23
D12.644.360.024.374 Suppressor of Cytokine Signaling Proteins 11
D12.644.360.024.437 Syntenins 2
D12.644.360.024.469 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.644.360.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.644.360.024.750 YAP-Signaling Proteins 5
D12.776 Proteins 2 577
D12.776.157 Carrier Proteins 546
D12.776.157.057 Adaptor Proteins, Signal Transducing 176
D12.776.157.057.001 5-Lipoxygenase-Activating Proteins 1
D12.776.157.057.002 14-3-3 Proteins 75
D12.776.157.057.003 A Kinase Anchor Proteins 1
D12.776.157.057.005 Arrestins 6
D12.776.157.057.006 CARD Signaling Adaptor Proteins 7
D12.776.157.057.010 Caveolin 1 14
D12.776.157.057.012 Caveolin 2 1
D12.776.157.057.014 Cortactin 1
D12.776.157.057.016 Crk-Associated Substrate Protein 7
D12.776.157.057.018 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.157.057.023 Discs Large Homolog 1 Protein
D12.776.157.057.028 Dishevelled Proteins 18
D12.776.157.057.039 GRB10 Adaptor Protein
D12.776.157.057.041 GRB2 Adaptor Protein 3
D12.776.157.057.043 GRB7 Adaptor Protein
D12.776.157.057.045 Insulin Receptor Substrate Proteins 6
D12.776.157.057.050 Interferon Regulatory Factors 11
D12.776.157.057.061 Interferon-Stimulated Gene Factor 3
D12.776.157.057.067 Kelch-Like ECH-Associated Protein 1 9
D12.776.157.057.072 Mediator Complex 5
D12.776.157.057.072.249 Cyclin C 1
D12.776.157.057.072.500 Cyclin-Dependent Kinase 8 1
D12.776.157.057.072.750 Mediator Complex Subunit 1 1
D12.776.157.057.073 mTOR Associated Protein, LST8 Homolog
D12.776.157.057.074 Myeloid Differentiation Factor 88 16
D12.776.157.057.078 Nod Signaling Adaptor Proteins 1
D12.776.157.057.080 Nuclear Receptor Coactivators 6
D12.776.157.057.086 Nuclear Receptor Interacting Protein 1 3
D12.776.157.057.092 Paxillin 5
D12.776.157.057.110 PII Nitrogen Regulatory Proteins
D12.776.157.057.124 Protein Inhibitors of Activated STAT 3
D12.776.157.057.139 Proto-Oncogene Proteins c-crk 1
D12.776.157.057.144 Proto-Oncogene Proteins c-vav 4
D12.776.157.057.150 Rabphilin-3A
D12.776.157.057.155 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.157.057.157 Regulatory-Associated Protein of mTOR
D12.776.157.057.158 Retinoblastoma Binding Proteins 3
D12.776.157.057.160 Sequestosome-1 Protein 3
D12.776.157.057.162 Shc Signaling Adaptor Proteins
D12.776.157.057.166 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.157.057.170 Smad Proteins 14
D12.776.157.057.186 STAT Transcription Factors 23
D12.776.157.057.249 Suppressor of Cytokine Signaling Proteins 11
D12.776.157.057.374 Syntenins 2
D12.776.157.057.437 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.157.057.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.157.057.750 YAP-Signaling Proteins 5
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.024 Adaptor Proteins, Signal Transducing 176
D12.776.476.024.034 5-Lipoxygenase-Activating Proteins 1
D12.776.476.024.050 14-3-3 Proteins 75
D12.776.476.024.069 A Kinase Anchor Proteins 1
D12.776.476.024.087 Angiomotins 1
D12.776.476.024.104 Arrestins 6
D12.776.476.024.139 CARD Signaling Adaptor Proteins 7
D12.776.476.024.280 Caveolin 1 14
D12.776.476.024.295 Caveolin 2 1
D12.776.476.024.311 Cortactin 1
D12.776.476.024.316 Crk-Associated Substrate Protein 7
D12.776.476.024.320 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.476.024.325 Discs Large Homolog 1 Protein
D12.776.476.024.330 Dishevelled Proteins 18
D12.776.476.024.377 GRB2 Adaptor Protein 3
D12.776.476.024.379 GRB7 Adaptor Protein
D12.776.476.024.380 GRB10 Adaptor Protein
D12.776.476.024.381 Homer Scaffolding Proteins 1
D12.776.476.024.382 Insulin Receptor Substrate Proteins 6
D12.776.476.024.385 Interferon Regulatory Factors 11
D12.776.476.024.386 Interferon-Stimulated Gene Factor 3
D12.776.476.024.387 Kelch-Like ECH-Associated Protein 1 9
D12.776.476.024.388 Mediator Complex 5
D12.776.476.024.388.249 Cyclin C 1
D12.776.476.024.388.500 Cyclin-Dependent Kinase 8 1
D12.776.476.024.388.750 Mediator Complex Subunit 1 1
D12.776.476.024.389 mTOR Associated Protein, LST8 Homolog
D12.776.476.024.390 Myeloid Differentiation Factor 88 16
D12.776.476.024.391 Nod Signaling Adaptor Proteins 1
D12.776.476.024.394 Nuclear Receptor Coactivators 6
D12.776.476.024.396 Nuclear Receptor Interacting Protein 1 3
D12.776.476.024.397 Paxillin 5
D12.776.476.024.400 PII Nitrogen Regulatory Proteins
D12.776.476.024.402 Protein Inhibitors of Activated STAT 3
D12.776.476.024.404 Proto-Oncogene Proteins c-crk 1
D12.776.476.024.407 Proto-Oncogene Proteins c-vav 4
D12.776.476.024.409 Rabphilin-3A
D12.776.476.024.411 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.476.024.414 Receptor Activity-Modifying Proteins 1
D12.776.476.024.419 Regulatory-Associated Protein of mTOR
D12.776.476.024.420 Retinoblastoma Binding Proteins 3
D12.776.476.024.422 Sequestosome-1 Protein 3
D12.776.476.024.424 Shc Signaling Adaptor Proteins
D12.776.476.024.426 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.476.024.428 Smad Proteins 14
D12.776.476.024.430 STAT Transcription Factors 23
D12.776.476.024.437 Suppressor of Cytokine Signaling Proteins 11
D12.776.476.024.468 Syntenins 2
D12.776.476.024.484 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.476.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.476.024.750 YAP-Signaling Proteins 5
D12.776.660 Nuclear Proteins 452
D12.776.660.049 Antennapedia Homeodomain Protein 1
D12.776.660.075 Ataxins 2
D12.776.660.100 BRCA1 Protein 101
D12.776.660.105 BRCA2 Protein 95
D12.776.660.167 CCAAT-Enhancer-Binding Proteins 11
D12.776.660.201 CDX2 Transcription Factor 3
D12.776.660.235 Chromosomal Proteins, Non-Histone 93
D12.776.660.264 Fanconi Anemia Complementation Group A Protein 1
D12.776.660.285 Fanconi Anemia Complementation Group D2 Protein 4
D12.776.660.289 Fanconi Anemia Complementation Group E Protein
D12.776.660.293 Fanconi Anemia Complementation Group F Protein
D12.776.660.323 Fanconi Anemia Complementation Group N Protein 4
D12.776.660.338 GADD45 Proteins
D12.776.660.352 Hepatocyte Nuclear Factors 5
D12.776.660.415 Homeobox Protein Nkx-2.2
D12.776.660.478 Host Cell Factor C1 2
D12.776.660.486 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.660.494 Inhibitor of Growth Protein 1
D12.776.660.502 Karyopherins 9
D12.776.660.526 Mad2 Proteins 1
D12.776.660.551 Mediator Complex 5
D12.776.660.551.249 Cyclin C 1
D12.776.660.551.500 Cyclin-Dependent Kinase 8 1
D12.776.660.551.750 Mediator Complex Subunit 1 1
D12.776.660.600 NF-kappa B 218
D12.776.660.625 Antigens, Nuclear 11
D12.776.660.650 Nuclear Matrix-Associated Proteins 2
D12.776.660.675 Nuclear Receptor Coactivators 6
D12.776.660.688 Nuclear Receptor Interacting Protein 1 3
D12.776.660.691 Nucleolin
D12.776.660.694 Nucleophosmin 17
D12.776.660.700 Oncogene Protein p55(v-myc) 1
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.740 Proliferating Cell Nuclear Antigen 60
D12.776.660.745 Promyelocytic Leukemia Protein 4
D12.776.660.750 Protamines 42
D12.776.660.760 Proto-Oncogene Proteins c-fos 61
D12.776.660.763 Proto-Oncogene Proteins c-jun 17
D12.776.660.764 Proto-Oncogene Proteins c-mdm2 65
D12.776.660.765 Proto-Oncogene Proteins c-myc 66
D12.776.660.767 Proto-Oncogene Proteins c-rel 2
D12.776.660.768 ran GTP-Binding Protein 4
D12.776.660.769 Retinoblastoma Binding Proteins 3
D12.776.660.770 Retinoblastoma-Like Protein p107 4
D12.776.660.794 Retinoblastoma-Like Protein p130 5
D12.776.660.807 Retinoblastoma Protein 52
D12.776.660.820 Silent Information Regulator Proteins, Saccharomyces cerevisiae
D12.776.660.823 Thyroid Nuclear Factor 1
D12.776.660.912 Tumor Protein p73 6

AT5G12230 protein, Arabidopsis Chemical MeSH Browser

CSE2 protein, S cerevisiae Chemical MeSH Browser

DRIP, VDR interacting protein complex Chemical MeSH Browser

GAL11 protein, S cerevisiae Chemical MeSH Browser

MDT-28 protein, C elegans Chemical MeSH Browser

MED10 protein, human Chemical MeSH Browser

MED11 protein, human Chemical MeSH Browser

MED12 protein, human Chemical MeSH Browser

MED13 protein, human Chemical MeSH Browser

MED13L protein, human Chemical MeSH Browser

MED14 protein, human Chemical MeSH Browser

MED15 protein, human Chemical MeSH Browser

MED16 protein, human Chemical MeSH Browser

MED16 protein, mouse Chemical MeSH Browser

MED17 protein, Drosophila Chemical MeSH Browser

MED18 protein, Arabidopsis Chemical MeSH Browser

MED19 protein, human Chemical MeSH Browser

MED2 protein, Arabidopsis Chemical MeSH Browser

MED2 protein, S cerevisiae Chemical MeSH Browser

MED20 protein, Arabidopsis Chemical MeSH Browser

MED21 protein, human Chemical MeSH Browser

MED22 protein, human Chemical MeSH Browser

MED23 protein, human Chemical MeSH Browser

MED24 protein, human Chemical MeSH Browser

MED25 protein, human Chemical MeSH Browser

MED26 protein, human Chemical MeSH Browser

MED27 protein, human Chemical MeSH Browser

MED28 protein, Arabidopsis Chemical MeSH Browser

MED28 protein, human Chemical MeSH Browser

MED29 protein, human Chemical MeSH Browser

MED30 protein, human Chemical MeSH Browser

MED31 protein, human Chemical MeSH Browser

MED31 protein, mouse Chemical MeSH Browser

MED4 protein, human Chemical MeSH Browser

MED6 protein, S cerevisiae Chemical MeSH Browser

MED6 protein, human Chemical MeSH Browser

MED7 protein, S cerevisiae Chemical MeSH Browser

MED7 protein, human Chemical MeSH Browser

MED8 protein, Arabidopsis Chemical MeSH Browser

MED8 protein, S cerevisiae Chemical MeSH Browser

MED8 protein, human Chemical MeSH Browser

MED8 protein, rat Chemical MeSH Browser

Med11 protein, S cerevisiae Chemical MeSH Browser

Med12 protein, mouse Chemical MeSH Browser

Med12 protein, zebrafish Chemical MeSH Browser

Med13 protein, mouse Chemical MeSH Browser

Med13l protein, mouse Chemical MeSH Browser

Med14 protein, S pombe Chemical MeSH Browser

Med14 protein, zebrafish Chemical MeSH Browser

Med17 protein, human Chemical MeSH Browser

Med20 protein, mouse Chemical MeSH Browser

Med22 protein, Drosophila Chemical MeSH Browser

Med23 protein, mouse Chemical MeSH Browser

Med24 protein, mouse Chemical MeSH Browser

Med25 protein, mouse Chemical MeSH Browser

Med27 protein, zebrafish Chemical MeSH Browser

Med28 protein, mouse Chemical MeSH Browser

Med30 protein, mouse Chemical MeSH Browser

Med31 protein, Drosophila Chemical MeSH Browser

Med6 protein, Drosophila Chemical MeSH Browser

Med6 protein, S pombe Chemical MeSH Browser

NUT1 protein, S cerevisiae Chemical MeSH Browser

NUT2 protein, S cerevisiae Chemical MeSH Browser

PGD1 protein, S cerevisiae Chemical MeSH Browser

RGR1 protein, S cerevisiae Chemical MeSH Browser

ROX3 protein, S cerevisiae Chemical MeSH Browser

SIN4 protein, S cerevisiae Chemical MeSH Browser

SOH1 protein, S cerevisiae Chemical MeSH Browser

SRB2 protein, S cerevisiae Chemical MeSH Browser

SRB4 protein, S cerevisiae Chemical MeSH Browser

SRB5 protein, S cerevisiae Chemical MeSH Browser

SRB6 protein, S cerevisiae Chemical MeSH Browser

SRB7 protein, S cerevisiae Chemical MeSH Browser

SSN2 protein, S cerevisiae Chemical MeSH Browser

pmc4 protein, S pombe Chemical MeSH Browser

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