Mediator Complex [mediátorový komplex]
- Terms
-
komplexy podobné mediátoru
proteinový komplex asociovaný s receptory thyreoidálních hormonů
transkripční mediátor
TRAP (protein asociovaný s receptory thyreoidálních hormonů)
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Mediator Transcription Complex
Mediator-Like Complex
Mediator-Like Complexes
Thyroid Hormone-Associated Protein Complex
TR-Associated Protein (TRAP) Complex
TRAP (Thyroid Hormone Associated Protein) Complex
A large protein complex which acts as a signaling adaptor protein that allows communication between the various regulatory and functional components of GENETIC TRANSCRIPTION including DNA POLYMERASE II; GENERAL TRANSCRIPTION FACTORS; and TRANSCRIPTION FACTORS that are bound to upstream ENHANCER ELEMENTS. The mediator complex was originally studied in YEAST where at least 21 subunits were identified. Many of the yeast subunits are homologs to proteins in higher organisms that are found associated with specific nuclear receptors such as THYROID HORMONE RECEPTORS and VITAMIN D RECEPTORS.
- DUI
- D056892 MeSH Browser
- CUI
- M0533184
- Previous indexing
- RNA Polymerase II (1994-2009); Transcription Factors (1994-2009)
- History note
- 2010; for TRAP (THYROID HORMONE ASSOCIATED PROTEIN) COMPLEX, TR-ASSOCIATED PROTEIN (TRAP) COMPLEX and THYROID HORMONE-ASSOCIATED PROTEIN COMPLEX use MEDIATOR COMPLEX SUBUNIT 1 2003-2009
- Public note
- 2010; TRAP (THYROID HORMONE ASSOCIATED PROTEIN) COMPLEX, TR-ASSOCIATED PROTEIN (TRAP) COMPLEX and THYROID HORMONE-ASSOCIATED PROTEIN COMPLEX were indexed under TRANSCRIPTION FACTORS 2003-2009
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