This review article is giving the overview on a pplication of liposomes as carriers of compounds. The properties of liposomes are summarized and their advantages for transport are highlighted. Liposomes as drug carriers can encapsulate the substance or drug, which is then purposefully released. This is the reason why liposomes have wide range of using, because this is promising step in research, not only in medicine, but also in pharmacy, biopharmacy, biophysics and cosmetics industries. Numerous substances including various drugs, hormones and genes can be transported by liposomes. They can, due to its structure, penetrate into the deeper layers of the skin, even in some organs without damaging them (for example in the brain, which is one of the hardest transport ever). The utilization of liposomes for targeted delivery of drugs, hormones and nanoparticles is mentioned

• Klíčová slova
• enkapsulace léčiv,
• MeSH
• biologický transport MeSH
• chemie farmaceutická MeSH
• léčivé přípravky MeSH
• lidé MeSH
• liposomy * MeSH
• systémy cílené aplikace léků * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• práce podpořená grantem MeSH
• přehledy MeSH

Routine cancer treatment often causes damage to whole human organism, because cytostatic drugs, which are used during the treatment and whose function is to stop growth of cancer cells, affect also healthy cells and untargeted tissues. Due to this fact, nanocarriers and targeted drug delivery have been recently studied. Side effects and organ damage can be reduced by using nanocarriers and targeted drug delivery. The aim of this assay was to monitor and characterize apoferritin as a nanocarrier for targeted drug delivery. In this work the surface of nanocarrier composed of apoferritin with encapsulated doxorubicin was modified with gold nanoparticles or chloroauric acid, conjugated with linker (HWR peptide) because of correct binding of the antibody and labeled with specific antibody. In this assay the resulting nanocarrier was studied with gel electrophoresis and fluorescent methods.

• Klíčová slova
• nanotransportér, teranostika,
• MeSH
• apoferritiny * MeSH
• doxorubicin MeSH
• elektroforéza MeSH
• ELISA MeSH
• fluorescenční protilátková technika MeSH
• imunoglobulin G MeSH
• kovové nanočástice * MeSH
• nanomedicína MeSH
• protilátky MeSH
• systémy cílené aplikace léků * MeSH
• zlato MeSH
• Publikační typ
• práce podpořená grantem MeSH