1. elektronické vydání 1 online zdroj (240 stran)
Monografie věnovaná malignitám peritoneálního povrchu je první soubornou prací na toto téma v domácím písemnictví. Význam léčby a počet indikací stále roste.; Kniha je určena chirurgům, onkologům, internistům, gastroenterologům a gynekologům.V publikaci je zpracována epidemiologie nádorů peritoneálního povrchu, aktuální pohled na patologickou klasifikaci, skórovací systémy pro popis rozsahu peritoneální karcinomatózy, možnosti diagnostiky peritoneálního rozsevu, indikační rozvaha a kritéria pro provedení CRS a HIPEC.
- Klíčová slova
- Chirurgie, ortopedie, traumatologie, Onkologie,
- MeSH
- peritoneální nádory MeSH
- NLK Obory
- onkologie
- gastroenterologie
1. vydání xx, 212 stran : ilustrace ; 24 cm
Publikace se zaměřuje na různé aspekty nádorů peritoneálního povrchu. Určeno odborné veřejnosti.; Kniha je určena chirurgům, onkologům, internistům, gastroenterologům a gynekologům.V publikaci je zpracována epidemiologie nádorů peritoneálního povrchu, aktuální pohled na patologickou klasifikaci, skórovací systémy pro popis rozsahu peritoneální karcinomatózy, možnosti diagnostiky peritoneálního rozsevu, indikační rozvaha a kritéria pro provedení CRS a HIPEC.
- MeSH
- peritoneální nádory MeSH
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- onkologie
- gastroenterologie
- NLK Publikační typ
- kolektivní monografie
PURPOSE: Bile duct injury (BDI) remains the most serious complication following cholecystectomy. However, the actual incidence of BDI in the Czech Republic remains unknown. Hence, we aimed to identify the incidence of major BDI requiring operative reconstruction after elective cholecystectomy in our region despite the prevailing modern 4 K Ultra HD laparoscopy and Critical View of Safety (CVS) standards implemented in daily surgical practice among the Czech population. METHODS: In the absence of a specific registry for BDI, we analysed data from The Czech National Patient Register of Reimbursed Healthcare Services, where all procedures are mandatorily recorded. We investigated 76,345 patients who were enrolled for at least a year and underwent elective cholecystectomy during the period from 2018-2021. In this cohort, we examined the incidence of major BDI following the reconstruction of the biliary tract and other complications. RESULTS: A total of 76,345 elective cholecystectomies were performed during the study period, and 186 major BDIs were registered (0.24%). Most elective cholecystectomies were performed laparoscopically (84.7%), with the remaining open (15.3%). The incidence of BDI was higher in the open surgery group (150 BDI/11700 cases/1.28%) than in laparoscopic cholecystectomy (36 BDI/64645 cases/0.06%). Furthermore, the total hospital stays with BDI after reconstruction was 13.6 days. However, the majority of laparoscopic elective cholecystectomies (57,914, 89.6%) were safe and standard procedures with no complications. CONCLUSION: Our study corroborates the findings of previous nationwide studies. Therefore, though laparoscopic cholecystectomy is reliable, the risks of BDI cannot be eliminated.
- MeSH
- cholecystektomie laparoskopická * škodlivé účinky MeSH
- cholecystektomie škodlivé účinky MeSH
- iatrogenní nemoci epidemiologie MeSH
- lidé MeSH
- poranění břicha * chirurgie MeSH
- registrace MeSH
- žlučové cesty chirurgie zranění MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
Nádory appendixu a pseudomyxom peritonea (PMP) jsou vzácné. Nejčastějším zdrojem PMP jsou perforované epiteliální nádory appendixu. Toto onemocnění je charakterizováno přítomností částečně na povrchy adherujícího mucinu různého stupně konzistence. Samotné apendikální mukokély jsou taktéž velmi vzácné a zpravidla jejich léčba zahrnuje pouze prostou apendektomii. Cílem této práce bylo vytvořit aktuální přehled doporučení pro diagnostiku a léčbu těchto malignit podle aktuálních doporučení skupiny PSOGI (The Peritoneal Surface Oncology Group International) a Modré knihy České onkologické společnosti ČLS JEP.
Appendiceal tumors and pseudomyxoma peritonei (PMP) are rare tumors. Perforated epithelial tumors of the appendix are the most common source of PMP. This disease is characterized by the presence of mucin of varying degrees of consistency, partially adherent to the surfaces. Appendiceal mucoceles themselves are also very rare and usually their treatment involves only a simple appendectomy. The aim of this study was to provide an up-to-date review of the recommendations for the diagnosis and treatment of these malignancies according to the current guidelines of The Peritoneal Surface Oncology Group International (PSOGI) and the Blue Book of the Czech Society for Oncology of the Czech Medical Association of J. E. Purkyně (ČOS ČLS JEP).
OBJECTIVES: The aim of this study is to evaluate the results of treatment of diffuse malignant peritoneal mesothelioma (DMPM) by cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) at a single center. METHODS: We conducted a retrospective single-center observational cohort study of consecutive patients with DMPM treated by CRS-HIPEC at the Department of Surgery I of the University Hospital in Olomouc, Czech Republic. RESULTS: Data on a total of 16 patients were processed. The study group of 16 patients had six (37.5 %) women. The mean age was approximately 62 years. Complete cytoreduction was achieved in all patients (100 %) (CC0: 75 %, CC1: 25 %). All patients underwent a closed form of HIPEC with cisplatin and doxorubicin for 90 min. The mean hospital stay was 13.5 days, including 4.38 days in the ICU (13.5 ± 5.07 and 4.38 ± 1.49, respectively). Major postoperative complications (CD grades 3–4) occurred in four patients (25 %). In-hospital mortality was 6.25 %. In the study group, the median overall survival was 20 months, and the median disease-free survival was 10.3 months. CONCLUSIONS: Also under the conditions at our specialized center, CRS-HIPEC is considered as an effective, affordable, and safe therapy with OS, DFS, morbidity, and mortality rates comparable to those reported in the literature (Tab. 5, Fig. 2, Ref. 28).
