- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
První vydání xxi, 397 stran : ilustrace, mapy, portréty, plány ; 24 cm
Kniha se zabývá životem a působením zakladatele genetiky Johanna Gregora Mendela.
- Konspekt
- Obecná genetika. Obecná cytogenetika. Evoluce
- Biografie
- NLK Obory
- genetika, lékařská genetika
- O autorovi
- Mendel, Johann Gregor, 1822-1884 Autorita
PURPOSE: En bloc resection of bladder tumors (ERBT) may improve staging quality and perioperative morbidity and influence tumor recurrence. This study was designed to evaluate the safety, efficacy, and recurrence rates of electrical versus laser en bloc resection of bladder tumors. METHODS: This European multicenter study included 221 patients at six academic hospitals. Transurethral ERBT was performed with monopolar/bipolar current or holmium/thulium laser energy. Staging quality measured by detrusor muscle involvement, various perioperative parameters, and 12-month follow-up data was analyzed. RESULTS: Electrical and laser ERBT were used to treat 156 and 65 patients, respectively. Median tumor size was 2.1 cm; largest tumor was 5 cm. Detrusor muscle was present in 97.3 %. A switch to conventional TURBT was significantly more frequent in the electrical ERBT group (26.3 vs. 1.5 %, p < 0.001). Median operation duration (25 min), postoperative irrigation (1 day), catheterization time (2 days), and hospitalization (3 days) were similar. Overall complication rate was low (Clavien ≥ 3, n = 6 [2.7 %]). Hemoglobin was significantly lower after electrical ERBT (p = 0.0013); however, overall hemoglobin loss was not clinically relevant (0.38 g/dl). Patients (n = 148) were followed for 12 months; 33 (22.3 %) had recurrences. In total, 63.6 % recurrences occurred outside the ERBT resection field. No difference was noted between ERBT groups. CONCLUSIONS: ERBT is safe and reliable regardless of the energy source and provides high-quality resections of tumors >1 cm. Recurrence rates did not differ between groups, and the majority of recurrences occurred outside the ERBT resection field.
- MeSH
- cystektomie * MeSH
- karcinom patologie chirurgie MeSH
- kohortové studie MeSH
- laserová terapie * MeSH
- lasery pevnolátkové terapeutické užití MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory močového měchýře patologie chirurgie MeSH
- senioři MeSH
- urotel * MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- srovnávací studie MeSH
- MeSH
- geny RAG-1 fyziologie genetika imunologie MeSH
- hlavní histokompatibilní komplex genetika účinky léků MeSH
- imunitní systém fyziologie imunologie MeSH
- lymfocyty imunologie MeSH
- molekulární evoluce MeSH
- obratlovci imunologie MeSH
- thymus fyziologie imunologie růst a vývoj MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
[1st ed.] XII, 46+2 s. : il.
2nd ed. VIII, 722 s. : il. ; 28 cm
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- alergologie a imunologie
508 s. : obr., tab., přeruš.bibliogr.
xv, 775 stran : ilustrace, tabulky. ; 29 cm
- MeSH
- imunogenetika MeSH
- Publikační typ
- monografie MeSH
