The association between pyoderma gangrenosum (PG) and myeloproliferative disorders is well established. The clinical management of pyoderma gangrenosum ulcers has always been a challenging practice, the mainstay of management of PG ulcers remains to be immune suppression or immune modulation, as well as management of possible underlying associated diseases, but no clear treatment protocol has been suggested. In this paper we are reporting a unique case of PG associated with myeloproliferative disorder and our treatment result based on treatment of underlying disease.
Karcinoidy sú zriedkavé nádory, ktoré sa správajú menej agresívne ako bežnejšie sa vyskytujúce črevné adenokarcinómy. Majú endokrinné vlastnosti. Niektorí autori obmedzujú pojem karcinoid na označenie črevných nádorov, iní sem začleňujú veľmi rôznorodú skupinu neuroendokrinných nádorov. Karcinoidy sú buď benígne nádory, alebo nádory s priaznivejšou prognózou ako karcinómy. Sú charakteristické afinitou k striebru a pozitívnymi reakciami s neurón - špecifickými markermi. Karcinoidy môžu produkovať biologicky aktívne hormóny.
Carcinoids are rare tumors that behave less aggressively than more common intestinal adenocarcinomas. They are of endocrine nature. Some authors restrict the term carcinoids to intestinal tumors and others include a large variety of neuroendocrine tumors. Carcinoids are either benign tumors or neoplasms with more favorable prognosis than carcinomas. They are characterized by silver affinity and positive reactions with neuron-specific markers. Carcinoids can product different biologically active hormones.
