The levels of prealbumin (PAB, transthyretin) were determined and evaluated in the cerebrospinal fluid (CSF) and serum in various subgroups of the multiple sclerosis (MS) patients. In severely disabled patients, serum PAB was elevated more frequently. CSF and serum PAB concentrations were higher in treated than in nontreated patients; the values above the upper reference limits were also more frequently found in treated patients. PAB index showed a tendency to decrease during the course of the disease. The routine determination of PAB in CSF and serum is, therefore, recommended to be recognized in MS patients as a substantial clinical value and, thus, be comprised, including also immunoglobulins and other parameters, into the spectrum of characteristics in Protein Panel.
- MeSH
- eozinofily imunologie MeSH
- glukosa MeSH
- krevní proteiny MeSH
- kyselina mléčná MeSH
- lidé MeSH
- meningitida diagnóza imunologie MeSH
- počet leukocytů MeSH
- T-lymfocyty pomocné-indukující imunologie MeSH
- T-lymfocyty imunologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- kazuistiky MeSH
A routine diagnostic procedure of cryptococcal meningitis using Alcian Blue and Nuclear Fast Red staining is described in a group of 16 patients. Cerebrospinal fluid findings, including clinical cytology, routine biochemistry and protein fractions, are presented.
- MeSH
- apolipoproteiny izolace a purifikace škodlivé účinky MeSH
- imunoglobulin M imunologie účinky léků MeSH
- lidé MeSH
- mozkomíšní mok imunologie MeSH
- nefelometrie a turbidimetrie metody využití MeSH
- nemoci nervového systému prevence a kontrola terapie MeSH
- proteiny v mozkomíšním moku izolace a purifikace škodlivé účinky MeSH
- Check Tag
- lidé MeSH
