Cíl: Naše předchozí randomizovaná studie trvající šest měsíců ukázala, že vegetariánská strava (V) má příznivý vliv na rizikové faktory kardiovaskulárních onemocnění (KVO). Ve srovnání se standardně doporučovanou diabetickou dietou (K) vede účinněji ke snížení inzulinové rezistence, snížení hmotnosti a objemu subkutánního i viscerálního tuku, poklesu LDL cholesterolu a ke zlepšení markerů oxidačního stresu a vybraných adipokinů. Naším cílem bylo sledovat pacienty jeden rok od ukončení studie, kdy pacienti v původní dietní intervenci nepokračovali a rok konzumovali srovnatelnou dietu. Metody: Šedesát dva diabetiků 2. typu, kteří dokončili studii, bylo pozváno na kontrolu jeden rok od ukončení studie. Měřili jsme jejich tělesnou hmotnost, obvod pasu, HbA1C a krevní lipidy. Výsledky: Čtyřicet čtyři pacientů (71 %) podstoupilo kontrolu. Antidiabetická medikace byla během jednoho roku od ukončení studie navýšena u 14 % pacientů ve V a u 26 % v K; terapie inzulinem byla zahájena u 5 % ve V a u 13 % v K. Hmotnost ani obvod pasu se ani v jedné skupině významně nezměnily. HbA1C stoupl (p ≤ 0,05) srovnatelně v obou skupinách (+0,49 ± 1,04 % ve V vs. +0,42 ± 0,8 % v K). Krevní lipidy se významně nezměnily ani v jedné skupině. Závěr: Naše výsledky ukazují částečné přetrvání pozitivních účinků vegetariánské stravy na rizikové faktory KVO oproti konvenční redukční diabetické dietě jeden rok od ukončení intervence.
Objective: Our previous 6-month, randomized study demonstrated the beneficial effect of a vegetarian (V) compared to a conventional diet (C) with similar caloric restriction on cardiovascular risk factors for patients with type 2 diabetes (T2D), namely increased insulin sensitivity, reduced body weight, reduced volume of visceral and subcutaneous fat, decreased LDL-cholesterol and improved oxidative stress markers and chosen adipokines. We conducted post-trial monitoring to determine whether the improved outcomes persisted 1 year after the end of the study. Methods: 62 subjects with T2D who completed the study were asked to come for a 1-year follow-up to measure weight, waist circumference, HbA1c and blood lipids. No attempts were made to maintain their previously assigned diets. Results: 44 patients (71%) attended the post-trial monitoring. Hypoglycemic agents were increased by 14% in V and by 26% in C; insulin therapy was introduced in 5% in V and in 13% in C one year after the end of the intervention. Neither weight nor waist circumference changed significantly in either group. HbA1c increased (p ≤ 0.05) similarly in both groups (+0.49 ± 1.04% in V vs. +0.42 ± 0.8% in C). Blood lipids did not change in either group. Conclusion: 1 year after the end of the intervention, the positive effects of a vegetarian diet on cardiovascular risk factors compared to a conventional diet were partially maintained.
- MeSH
- Diabetes Mellitus, Type 2 * diet therapy etiology MeSH
- Diet, Vegetarian * MeSH
- Glycated Hemoglobin diagnostic use MeSH
- Hypoglycemic Agents therapeutic use MeSH
- Cardiovascular Diseases prevention & control MeSH
- Humans MeSH
- Lipids blood MeSH
- Follow-Up Studies MeSH
- Nutrition Therapy methods statistics & numerical data MeSH
- Risk Factors MeSH
- Body Weights and Measures statistics & numerical data MeSH
- Check Tag
- Humans MeSH
- Publication type
- Evaluation Study MeSH
- Research Support, Non-U.S. Gov't MeSH
Background: The United Nations' Global Population Pyramid is undertaking a shift from pyramid to cube. The concomitant decline in fertility and mortality rates produces a higher portion of older people, and, thus, an increased number of deaths due to cancer and cardiovascular disease (CVD). Limited studies have investigated the effect of health care services on longevity. In this work, findings from studies throughout the world are presented and re-analysed in order to evaluate the effect of health care services on population's health status. Methods: Studies that have assessed the associations of nutritional and other health care services (i.e., physicians supply, technical support, inter-collaboration) on longevity and health status were retrieved (searches in PubMed, EMBASE, Scopus, up to January 2010), and summarized here. Results: Few studies, mostly located in the US and the UK, have evaluated the role of health care services on population's health status. The majority of the studies reported a beneficial association between the frequency of physicians and mortality, while some other studies reported weak or no associations between physician's supply and longevity. Also nutritional services (screening) seem to promote better clinical outcome. Conclusion: Although very few data are available, it seems that there is a positive correlation between the quality and quantity of health care services and longevity. Strong primary health care seems to be effective on the population's health outcome. Active health policy and enhance-ment of health and nutritional services within the health care system may contribute to improved population's health and their overall quality of life.
- MeSH
- Longevity MeSH
- Quality of Life MeSH
- Humans MeSH
- Nutrition Therapy statistics & numerical data MeSH
- Primary Health Care statistics & numerical data utilization MeSH
- Developed Countries statistics & numerical data MeSH
- Health Status MeSH
- Health Services statistics & numerical data utilization MeSH
- Check Tag
- Humans MeSH
