Dlhodobé podávanie antipsychotík patrí medzi štandardné postupy pri liečbe schizofrénie. Jej úspešnosť je ovplyvnená mnohými faktormi – prevládajúcou symptomatikou a typom schizofrénie, adherenciou pacienta, prirodzeným priebehom ochorenia. Tieto faktory komplikujú aj vyhodnocovanie úspešnosti liečby hlavne vtedy, ak je toto vyhodnocovanie založené na požiadavkách medicíny založenej na dôkazoch. V článku upozorňujeme na niektoré oblasti v dlhodobej liečbe psychofarmakami, ktoré môžu pomôcť pri porozumení a prenose poznatkov z publikovaných štúdií do klinickej praxe.
Long-term treatment with antipsychotics is a standard recommendation in the treatment of schizophrenia. The effectiveness of treatment depends on many factors like prevailing symptomatology and type of schizophrenia, patient's adherence to treatment and natural course of schizophrenia. These factors interfere with an evaluation of treatment effect mainly if the principles of Evidence Based Medicine are applied. The main goal of the article is to mention some aspects of long-term antipsychotic treatment that could help in understanding of results in published clinical studies and transforming these data to clinical practice.
- MeSH
- Antipsychotic Agents administration & dosage pharmacokinetics pharmacology MeSH
- Disease Attributes MeSH
- Humans MeSH
- Evidence-Based Medicine MeSH
- Progressive Patient Care standards statistics & numerical data MeSH
- Recurrence MeSH
- Schizophrenia diagnosis drug therapy MeSH
- Secondary Prevention MeSH
- Dose-Response Relationship, Drug MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
