- MeSH
- General Practice * economics organization & administration MeSH
- Publication type
- Newspaper Article MeSH
- Interview MeSH
elektronický časopis
Based on studies of the cell cycle in tissue cultures of cancer cell lines and cells from normal tissue interference in the regulatory network of pRB/cdk4/cyclin D1/p16 in combination with the tumour suppressor gene p53 was investigated. It was shown that overexpression of p53 and p16, but not p53 on its own, induced apoptotic cell death only in tumour cells. Gene transfer of the same two genes to tumours transplanted subcutaneously in mice also caused fast regression of some of the tumours.
- MeSH
- Apoptosis * MeSH
- Genetic Therapy * MeSH
- Genetic Vectors MeSH
- Genes, p16 * MeSH
- Genes, p53 * MeSH
- Humans MeSH
- Adenoviruses, Human * genetics MeSH
- Mice MeSH
- Tumor Cells, Cultured MeSH
- Gene Transfer Techniques * MeSH
- Neoplasm Transplantation MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Mice MeSH
- Animals MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
^^^sv.
- MeSH
- Drug Industry MeSH
- Statistics as Topic MeSH
- Geographicals
- Denmark MeSH
- Conspectus
- Farmacie. Farmakologie
Acta neurologica scandinavica ; Supplementum Vol. 87. 143
20 s. : obr. ; 28 cm
- MeSH
- Hippocampus physiopathology MeSH
- Signal Transduction MeSH
- Ischemic Attack, Transient physiopathology MeSH
- Conspectus
- Lékařské vědy. Lékařství
- NML Fields
- neurologie
- patologie
- fyziologie
- MeSH
- Economics, Nursing * MeSH
- Salaries and Fringe Benefits MeSH
- Nursing trends MeSH
- Life Style MeSH
- Publication type
- Interview MeSH
- Geographicals
- Czechoslovakia MeSH
- MeSH
- Hemodialysis Units, Hospital organization & administration MeSH
- Humans MeSH
- International Cooperation MeSH
- Nursing, Supervisory * MeSH
- Nursing trends MeSH
- Societies, Nursing organization & administration MeSH
- Check Tag
- Humans MeSH
- Publication type
- Interview MeSH
- Geographicals
- Czechoslovakia MeSH
- Denmark MeSH
Acta ophthalmologica ; Supplement Vol. 70. 203
40 s. : grafy, tab. ; 25 cm
- MeSH
- Diabetic Retinopathy MeSH
- Conspectus
- Lékařské vědy. Lékařství
- NML Fields
- vnitřní lékařství
- oftalmologie
