Effectiveness of SmartGuard Technology in the Prevention of Nocturnal Hypoglycemia After Prolonged Physical Activity
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu srovnávací studie, časopisecké články, pozorovací studie, práce podpořená grantem
PubMed
28520532
DOI
10.1089/dia.2016.0459
Knihovny.cz E-zdroje
- Klíčová slova
- Hypoglycemia, Physical activity, Predictive algorithm., Sensor-augmented pump therapy,
- MeSH
- algoritmy MeSH
- ambulantní monitorování * škodlivé účinky MeSH
- chování dětí * MeSH
- činnosti denního života MeSH
- cvičení * MeSH
- diabetes mellitus 1. typu krev dietoterapie farmakoterapie metabolismus MeSH
- diabetická dieta škodlivé účinky MeSH
- dietní sacharidy škodlivé účinky metabolismus MeSH
- dítě MeSH
- hyperglykemie prevence a kontrola MeSH
- hypoglykemie epidemiologie etiologie prevence a kontrola MeSH
- incidence MeSH
- inzulinové infuzní systémy * škodlivé účinky MeSH
- kombinovaná terapie škodlivé účinky MeSH
- krevní glukóza analýza MeSH
- lidé MeSH
- mladiství MeSH
- sporty * MeSH
- testování materiálů MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
- Názvy látek
- dietní sacharidy MeSH
- krevní glukóza MeSH
BACKGROUND: The prevention of postexercise nocturnal hypoglycemia after prolonged physical activity using sensor-augmented pump (SAP) therapy with predictive low-glucose management (PLGM) has not been well studied. We conducted a study at a pediatric diabetes camp to determine whether a SAP with PLGM reduces the frequency of nocturnal hypoglycemia after prolonged physical activity more effectively than a SAP with a carbohydrate intake algorithm. METHODS: During a 1-week sport camp, 20 children (aged 10-13 years) with type 1 diabetes (T1D) managed by SAP therapy either with (n = 7) or without PLGM (n = 13) were studied. The hypoglycemia management strategy and the continuous glucose monitoring (CGM)/PLGM settings were standardized. The incidence, severity, and duration of hypoglycemia and carbohydrate intake were documented and compared. RESULTS: The PLGM system was activated on 78% of all nights (once per night on average). No difference was found between the SAP and PLGM groups in the mean overnight glucose curve or mean morning glucose (7.8 ± 2 mmol/L vs. 7.4 ± 3 mmol/L). There was no difference in the frequency and severity of hypoglycemia. However, the SAP group consumed significantly more carbohydrates to prevent and treat hypoglycemia than those in the PLGM group; the values were 10 ± 2 and 1 ± 2 gS (P < 0.0001) in the SAP and PLGM groups, respectively. Moreover, the SAP group spent a significantly longer time in hypoglycemia (64 ± 2 min vs. 38 ± 2 min, P < 0.05). We observed a difference in the time distribution of nocturnal hypoglycemia (10 to 12 p.m. in the PLGM group and 3 to 7 a.m. in the SAP group, P < 0.05). CONCLUSION: With PLGM system, euglycemia after prolonged physical activity was largely maintained with a minimal carbohydrate intake.
3rd Department of Internal Medicine 1st Faculty of Medicine Charles University Prague Czech Republic
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