Kardiovize Brno 2030, a prospective cardiovascular health study in Central Europe: Methods, baseline findings and future directions
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
- Keywords
- Central and Eastern Europe, Prospective cohort study, cardiovascular risk factors, urban population,
- MeSH
- Time Factors MeSH
- Adult MeSH
- Cardiovascular Diseases diagnosis epidemiology MeSH
- Comorbidity MeSH
- Middle Aged MeSH
- Humans MeSH
- Prevalence MeSH
- Prospective Studies MeSH
- Risk Factors MeSH
- Sex Distribution MeSH
- Socioeconomic Factors MeSH
- Age Distribution MeSH
- Research Design MeSH
- Urban Health * MeSH
- Health Surveys MeSH
- Life Style MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic epidemiology MeSH
Background Atherosclerotic cardiovascular disease is highly prevalent in Eastern and Central Europe, where the incidence is the highest in the world. The Kardiovize Brno 2030 study was designed as a prospective cohort study to investigate the complex relationships of cardiovascular disease and outcomes with a range of biological, psychosocial, environmental, behavioral, and economic factors in an urban population of the Czech Republic. Methods We randomly selected a 1% sample of the city of Brno residents aged 25-64 years stratified by sex and age. The study assessed traditional and novel cardiovascular disease risk factors, including sociodemographic and smoking status, physical activity, diet, depression, stress, body fat, cardio-ankle vascular index, and intima media thickness, complemented by blood tests; biological samples were stored for future analyses. Results The study enrolled 2160 participants (54.8% women), with a mean age of 47 ± 11.3 years. They were mostly full-time employed (75.6%) and married (62.1%). Hyperlipidemia was highly prevalent (70.7% in men, and 67.1% in women, NS). Hypertension and diabetes mellitus were more prevalent in men than in women (54.3% vs. 38.7% and 7.1% vs. 3.5%, respectively, P < 0.001 for both). A total of 25.3% of men and 21.9% of women smoked, whereas 20.0% and 43.0% of men and 18.1% and 26.6% of women were obese and overweight, respectively. Conclusions Cardiovascular risk factors are highly prevalent in the city of Brno, an urban population from Central Europe. The Kardiovize Brno 2030 study will provide unique multidimensional and longitudinal cardiovascular health data from a region where epidemiological studies are scarce.
Department of Cardiovascular Medicine Mayo Clinic USA
Department of Public Health Masaryk University Czech Republic
International Clinical Research Center St Anne's University Hospital Czech Republic
References provided by Crossref.org
Social and environmental stressors of cardiometabolic health
The long-term effects of consecutive COVID-19 waves on mental health
Pharmacogenomic profile of a central European urban random population-Czech population
Association of Self-Reported Depression Symptoms with Physical Activity Levels in Czechia
Investigating cognition in midlife
Lipidomic Profiling Identifies Signatures of Poor Cardiovascular Health
Risk Factors Underlying COVID-19 Lockdown-Induced Mental Distress
Circulating histone signature of human lean metabolic-associated fatty liver disease (MAFLD)
