Advances in Surface Plasmon Resonance Imaging and Microscopy and Their Biological Applications
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- Keywords
- biomolecular interaction analysis, detection of biomolecules, imaging, microscopy, optical biosensor, surface plasmon, surface plasmon resonance,
- MeSH
- Bacteria isolation & purification ultrastructure MeSH
- Equipment Design MeSH
- Humans MeSH
- Protein Interaction Mapping instrumentation methods MeSH
- Microscopy instrumentation methods MeSH
- Nucleic Acids analysis MeSH
- Surface Plasmon Resonance instrumentation methods MeSH
- Proteins analysis MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Nucleic Acids MeSH
- Proteins MeSH
Surface plasmon resonance microscopy and imaging are optical methods that enable observation and quantification of interactions of nano- and microscale objects near a metal surface in a temporally and spatially resolved manner. This review describes the principles of surface plasmon resonance microscopy and imaging and discusses recent advances in these methods, in particular, in optical platforms and functional coatings. In addition, the biological applications of these methods are reviewed. These include the detection of a broad variety of analytes (nucleic acids, proteins, bacteria), the investigation of biological systems (bacteria and cells), and biomolecular interactions (drug-receptor, protein-protein, protein-DNA, protein-cell).
References provided by Crossref.org
