Tumor Suppressor Protein p53 [nádorový supresorový protein p53]

topical
754
Terms

buněčný nádorový antigen p53
fosfoprotein pp53
onkoprotein p53
protein TP53
protein TRP53

 

Cellular Tumor Antigen p53
Oncoprotein p53
p53 Antigen
p53 Tumor Suppressor Protein
pp53 Phosphoprotein
TP53 Protein
TRP53 Protein

Persistent link   https://www.medvik.cz/link/D016159
Definition

Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.

DUI
D016159 MeSH Browser
CUI
M0024670
Previous indexing
Neoplasm Proteins (1981-1989); Oncogene Products (1990); Phosphoproteins (1981-1990)
History note
2005(1991);
Public note
2005; see TP53 PROTEIN 1991-2005; TP53 PROTEIN was indexed under NERVE TISSUE PROTEINS & NEOPLASM PROTEINS 1992-1993

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 5
AG
agonists 1
AN
analysis 85
AI
antagonists & inhibitors 9
BI
biosynthesis 16
BL
blood 11
CF
cerebrospinal fluid 0
CS
chemical synthesis 1
CH
chemistry 56
CL
classification 0
DF
deficiency 11
DE
drug effects 16
EC
economics 0
GE
genetics 318
HI
history 1
IM
immunology 27
IP
isolation & purification 12
ME
metabolism 278
PK
pharmacokinetics 1
PD
pharmacology 1
PH
physiology 51
PO
poisoning 0
RE
radiation effects 3
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 0
TO
toxicity 0
UL
ultrastructure 4
UR
urine 0

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 575
D12.776.157 Carrier Proteins 546
D12.776.157.687 Poly-ADP-Ribose Binding Proteins 5
D12.776.157.687.063 Apoptosis Inducing Factor 9
D12.776.157.687.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.157.687.157 CCCTC-Binding Factor 2
D12.776.157.687.173 Centromere Protein A 2
D12.776.157.687.188 Centromere Protein B
D12.776.157.687.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.157.687.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.157.687.375 DNA Topoisomerases, Type I 24
D12.776.157.687.438 DNA-Activated Protein Kinase 14
D12.776.157.687.450 Heat Shock Transcription Factors 1
D12.776.157.687.462 Heterogeneous Nuclear Ribonucleoprotein A1
D12.776.157.687.485 Histones 366
D12.776.157.687.493 Ku Autoantigen 5
D12.776.157.687.495 MRE11 Homologue Protein 6
D12.776.157.687.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.157.687.497 NF-kappa B p52 Subunit 2
D12.776.157.687.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.157.687.575 Nitric Oxide Synthase Type II 75
D12.776.157.687.613 Telomerase 189
D12.776.157.687.650 Tumor Suppressor Protein p53 754
D12.776.157.687.750 Werner Syndrome Helicase 2
D12.776.157.687.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.157.687.875 Xeroderma Pigmentosum Group A Protein 2
D12.776.260 DNA-Binding Proteins 553
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.103 Basic Helix-Loop-Helix Transcription Factors 61
D12.776.260.108 Basic-Leucine Zipper Transcription Factors 18
D12.776.260.114 Butyrate Response Factor 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.158 Early Growth Response Transcription Factors 1
D12.776.260.197 Elongin
D12.776.260.235 Erythroid-Specific DNA-Binding Factors 1
D12.776.260.246 Factor For Inversion Stimulation Protein
D12.776.260.254 G-Box Binding Factors
D12.776.260.257 GATA Transcription Factors 2
D12.776.260.260 Heat Shock Transcription Factors 1
D12.776.260.262 Hepatocyte Nuclear Factors 5
D12.776.260.268 Heterogeneous-Nuclear Ribonucleoprotein K
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 122
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.457 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.260.495 Integration Host Factors
D12.776.260.504 Interferon Regulatory Factors 11
D12.776.260.513 Interferon-Stimulated Gene Factor 3
D12.776.260.522 Kruppel-Like Transcription Factors 26
D12.776.260.525 Ku Autoantigen 5
D12.776.260.527 Leucine-Responsive Regulatory Protein
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 5
D12.776.260.532 Matrix Attachment Region Binding Proteins 9
D12.776.260.534 MDS1 and EVI1 Complex Locus Protein 2
D12.776.260.536 Methyl-CpG-Binding Protein 2 12
D12.776.260.538 Minichromosome Maintenance 1 Protein 1
D12.776.260.539 MRE11 Homologue Protein 6
D12.776.260.540 MutL Proteins
D12.776.260.556 MutS Proteins
D12.776.260.560 Myeloid-Lymphoid Leukemia Protein 39
D12.776.260.600 NF-kappa B 209
D12.776.260.605 NFI Transcription Factors 6
D12.776.260.615 Nuclear Respiratory Factors
D12.776.260.623 Nucleobindins 2
D12.776.260.630 Oncogene Protein p55(v-myc) 1
D12.776.260.640 Origin Recognition Complex 1
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.645 Paired Box Transcription Factors 21
D12.776.260.650 Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
D12.776.260.655 POU Domain Factors 4
D12.776.260.660 Proto-Oncogene Proteins c-bcl-6 3
D12.776.260.665 Proto-Oncogene Proteins c-ets 19
D12.776.260.675 Proto-Oncogene Proteins c-myb 30
D12.776.260.682 Proto-Oncogene Proteins c-rel 2
D12.776.260.690 Proto-Oncogene Proteins c-sis 3
D12.776.260.693 PTB-Associated Splicing Factor
D12.776.260.695 Rad51 Recombinase 42
D12.776.260.696 Rad52 DNA Repair and Recombination Protein 9
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.733 TEA Domain Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 24
D12.776.260.750 Toll-Like Receptor 9 15
D12.776.260.755 Trans-Activators 110
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.768 Transcription Factor MTF-1
D12.776.260.775 Transcription Factors, General 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.805 Tumor Suppressor p53-Binding Protein 1 16
D12.776.260.820 Tumor Suppressor Protein p53 754
D12.776.260.885 Tumor Protein p73 6
D12.776.260.950 Winged-Helix Transcription Factors
D12.776.260.963 X-ray Repair Cross Complementing Protein 1 9
D12.776.260.975 Xeroderma Pigmentosum Group A Protein 2
D12.776.624 Neoplasm Proteins 411
D12.776.624.776 Tumor Suppressor Proteins 265
D12.776.624.776.010 Adenomatous Polyposis Coli Protein 13
D12.776.624.776.021 DCC Receptor
D12.776.624.776.051 Fanconi Anemia Complementation Group N Protein 4
D12.776.624.776.100 BRCA1 Protein 101
D12.776.624.776.101 BRCA2 Protein 95
D12.776.624.776.355 Cyclin-Dependent Kinase Inhibitor Proteins 42
D12.776.624.776.418 Cystatin M
D12.776.624.776.482 Deubiquitinating Enzyme CYLD 1
D12.776.624.776.503 Inhibitor of Growth Protein 1
D12.776.624.776.523 Kangai-1 Protein 1
D12.776.624.776.546 Kisspeptins 6
D12.776.624.776.610 Neurofibromin 1 14
D12.776.624.776.612 Neurofibromin 2 3
D12.776.624.776.633 Patched Receptors
D12.776.624.776.654 Promyelocytic Leukemia Protein 4
D12.776.624.776.695 PTEN Phosphohydrolase 49
D12.776.624.776.717 Retinoblastoma-Like Protein p107 4
D12.776.624.776.735 Retinoblastoma-Like Protein p130 5
D12.776.624.776.745 Retinoblastoma Protein 52
D12.776.624.776.760 Smad4 Protein 7
D12.776.624.776.766 Tuberous Sclerosis Complex 1 Protein 7
D12.776.624.776.769 Tuberous Sclerosis Complex 2 Protein 9
D12.776.624.776.772 Tumor Suppressor Protein p14ARF 4
D12.776.624.776.775 Tumor Suppressor Protein p53 754
D12.776.624.776.820 Tumor Protein p73 6
D12.776.624.776.865 Von Hippel-Lindau Tumor Suppressor Protein 30
D12.776.624.776.960 WT1 Proteins 29
D12.776.624.776.980 WW Domain-Containing Oxidoreductase 1
D12.776.660 Nuclear Proteins 451
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.720.063 Apoptosis Inducing Factor 9
D12.776.660.720.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.660.720.157 CCCTC-Binding Factor 2
D12.776.660.720.173 Centromere Protein A 2
D12.776.660.720.188 Centromere Protein B
D12.776.660.720.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.660.720.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.660.720.375 DNA Topoisomerases, Type I 24
D12.776.660.720.438 DNA-Activated Protein Kinase 14
D12.776.660.720.462 Heat Shock Transcription Factors 1
D12.776.660.720.485 Histones 366
D12.776.660.720.493 Ku Autoantigen 5
D12.776.660.720.495 MRE11 Homologue Protein 6
D12.776.660.720.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.660.720.497 NF-kappa B p52 Subunit 2
D12.776.660.720.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.660.720.575 Nitric Oxide Synthase Type II 75
D12.776.660.720.613 Telomerase 189
D12.776.660.720.650 Tumor Suppressor Protein p53 754
D12.776.660.720.750 Werner Syndrome Helicase 2
D12.776.660.720.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.660.720.875 Xeroderma Pigmentosum Group A Protein 2
D12.776.744 Phosphoproteins 187
D12.776.744.049 bcl-Associated Death Protein 2
D12.776.744.100 BRCA1 Protein 101
D12.776.744.150 Caseins 80
D12.776.744.287 Caveolin 1 14
D12.776.744.356 Caveolin 2 1
D12.776.744.360 CDC2 Protein Kinase 36
D12.776.744.390 Cortactin 1
D12.776.744.425 Crk-Associated Substrate Protein 7
D12.776.744.459 Dopamine and cAMP-Regulated Phosphoprotein 32 3
D12.776.744.476 Fanconi Anemia Complementation Group A Protein 1
D12.776.744.484 Fanconi Anemia Complementation Group D2 Protein 4
D12.776.744.488 Fanconi Anemia Complementation Group G Protein 2
D12.776.744.493 Focal Adhesion Kinase 1 3
D12.776.744.527 Integrin-Binding Sialoprotein 1
D12.776.744.562 Interferon Regulatory Factor-3 3
D12.776.744.631 Interferon Regulatory Factor-7 3
D12.776.744.665 Paxillin 5
D12.776.744.700 Phosvitin
D12.776.744.736 Plectin 8
D12.776.744.741 Smad Proteins, Receptor-Regulated 1
D12.776.744.747 Retinoblastoma-Like Protein p107 4
D12.776.744.755 Retinoblastoma-Like Protein p130 5
D12.776.744.770 Retinoblastoma Protein 52
D12.776.744.772 Stathmin 4
D12.776.744.840 Synapsins 2
D12.776.744.845 Tumor Suppressor Protein p53 754
D12.776.744.925 Vitellogenins 20
D12.776.744.962 Zyxin

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