Proto-Oncogene Proteins c-kit [protoonkogenní proteiny c-kit]
- Terms
-
antigeny CD117
c-kit protein
c-kit receptor
kit proto-onkogenní proteiny
p145(c-kit)
p145c-kit
receptor SCF
-
Antigens, CD117
c-kit Protein
c-kit Receptor
CD117 Antigen
CD117 Antigens
kit Proto-Oncogene Protein
p145 c-kit
p145(c-kit)
p145c-kit
Proto-Oncogene Protein c-kit
Proto-Oncogene Protein kit
Receptor, Stem Cell Factor
SCF Receptor
Stem Cell Factor Receptor
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.
- DUI
- D019009 MeSH Browser
- CUI
- M0028387
- Previous indexing
- Proto-Oncogene Proteins (1989-1995); Receptor Protein-Tyrosine Kinase (1994-1995); Receptors, Colony-Stimulating Factor (1991-1995)
- History note
- 2000(1996); use PROTO-ONCOGENE PROTEIN c-KIT (NM) 1989-1995
- Public note
- 2000; see PROTO-ONCOGENE PROTEINS C-KIT 1999-1996; PROTO-ONCOGENE PROTEIN KIT (now PROTO-ONCOGENE PROTEIN C-KIT) was indexed under RECEPTOR PROTEIN-TYROSINE KINASE 1994-1995; RECEPTORS, COLONY-STIMULATING FACTOR 1991-1995; & PROTO-ONCOGENE PROTEINS 1989-1995
Allowable subheadings
- AD
- administration & dosage 4
- AE
- adverse effects 3
- AG
- agonists 0
- AN
- analysis 7
- AI
- antagonists & inhibitors 10
- BI
- biosynthesis 2
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 5
- EC
- economics 0
- GE
- genetics 33
- HI
- history 0
- IM
- immunology 2
- IP
- isolation & purification 3
- ME
- metabolism 10
- PK
- pharmacokinetics 3
- PD
- pharmacology 1
- PH
- physiology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 4
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0