Proto-Oncogene Proteins c-mdm2 [protoonkogenní proteiny c-mdm2]

topical
65
Terms

protein Mdm2
protoonkogenní protein c-mdm2

 

c-mdm2 Proto-Oncogene Protein
Double Minute 2 Protein
Mdm-2 Protein
Mdm2 Protein
MDMX Protein
Murine Double Minute 2 Protein

Persistent link   https://www.medvik.cz/link/D051736
Definition

An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.

DUI
D051736 MeSH Browser
CUI
M0187954
History note
2006(1991)
Public note
2006; PROTO-ONCOGENE PROTEINS C-MDM2 was indexed under PROTO-ONCOGENE PROTEINS 2005, & under NUCLEAR PROTEINS 1991-2005, & under NEOPLASM PROTEINS 1991-2004

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis 2
AI
antagonists & inhibitors 4
BI
biosynthesis 4
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 5
CL
classification
DF
deficiency 1
DE
drug effects
EC
economics
GE
genetics 35
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 37
PK
pharmacokinetics
PD
pharmacology
PH
physiology 3
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 1
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 551
D08.811.464 Ligases 33
D08.811.464.938 Ubiquitin-Protein Ligase Complexes 25
D08.811.464.938.750 Ubiquitin-Protein Ligases 81
D08.811.464.938.750.092 Anaphase-Promoting Complex-Cyclosome 12
D08.811.464.938.750.186 Fanconi Anemia Complementation Group L Protein 2
D08.811.464.938.750.210 Inhibitor of Apoptosis Proteins 29
D08.811.464.938.750.233 Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein 1
D08.811.464.938.750.257 Nedd4 Ubiquitin Protein Ligases
D08.811.464.938.750.280 Polycomb Repressive Complex 1 6
D08.811.464.938.750.374 Proto-Oncogene Proteins c-cbl 6
D08.811.464.938.750.562 Proto-Oncogene Proteins c-mdm2 65
D08.811.464.938.750.656 Receptors, Autocrine Motility Factor 1
D08.811.464.938.750.703 Seven in Absentia Proteins
D08.811.464.938.750.750 SKP Cullin F-Box Protein Ligases 14
D08.811.464.938.750.782 Tripartite Motif-Containing Protein 28
D08.811.464.938.750.813 Tumor Necrosis Factor alpha-Induced Protein 3 2
D08.811.464.938.750.875 Von Hippel-Lindau Tumor Suppressor Protein 31
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.624 Neoplasm Proteins 413
D12.776.624.664 Oncogene Proteins 125
D12.776.624.664.700 Proto-Oncogene Proteins 264
D12.776.624.664.700.013 Axl Receptor Tyrosine Kinase
D12.776.624.664.700.025 Bcl-2-Like Protein 11 5
D12.776.624.664.700.037 c-Mer Tyrosine Kinase 2
D12.776.624.664.700.049 Chemokine CXCL1 7
D12.776.624.664.700.100 Cyclin D1 86
D12.776.624.664.700.110 Fibroblast Growth Factor 4 2
D12.776.624.664.700.112 Fibroblast Growth Factor 6
D12.776.624.664.700.114 fms-Like Tyrosine Kinase 3 53
D12.776.624.664.700.117 Janus Kinase 2 80
D12.776.624.664.700.119 KRIT1 Protein
D12.776.624.664.700.120 Kruppel-Like Factor 6 1
D12.776.624.664.700.123 Lipocalin-2 21
D12.776.624.664.700.128 Lymphocyte Specific Protein Tyrosine Kinase p56(lck) 10
D12.776.624.664.700.129 MDS1 and EVI1 Complex Locus Protein 2
D12.776.624.664.700.130 MutS Homolog 2 Protein 17
D12.776.624.664.700.148 Myeloid-Lymphoid Leukemia Protein 39
D12.776.624.664.700.158 N-Myc Proto-Oncogene Protein 9
D12.776.624.664.700.163 Pre-B-Cell Leukemia Transcription Factor 1 2
D12.776.624.664.700.165 B-Cell Lymphoma 3 Protein
D12.776.624.664.700.166 Proto-Oncogene Mas 3
D12.776.624.664.700.167 Proto-Oncogene Proteins c-abl 7
D12.776.624.664.700.168 Proto-Oncogene Proteins c-akt 120
D12.776.624.664.700.169 Proto-Oncogene Proteins c-bcl-2 148
D12.776.624.664.700.170 Proto-Oncogene Proteins c-bcl-6 3
D12.776.624.664.700.171 Proto-Oncogene Proteins c-bcr 19
D12.776.624.664.700.172 Proto-Oncogene Proteins c-cbl 6
D12.776.624.664.700.174 Proto-Oncogene Proteins c-crk 1
D12.776.624.664.700.175 Proto-Oncogene Proteins c-ets 19
D12.776.624.664.700.177 Proto-Oncogene Proteins c-fes
D12.776.624.664.700.179 Proto-Oncogene Proteins c-fos 62
D12.776.624.664.700.180 Proto-Oncogene Proteins c-fyn 4
D12.776.624.664.700.181 Proto-Oncogene Proteins c-hck 1
D12.776.624.664.700.182 Proto-Oncogene Proteins c-jun 18
D12.776.624.664.700.183 Proto-Oncogene Proteins c-kit 77
D12.776.624.664.700.184 Proto-Oncogene Proteins c-maf 1
D12.776.624.664.700.185 Proto-Oncogene Proteins c-mdm2 65
D12.776.624.664.700.186 Proto-Oncogene Proteins c-met 30
D12.776.624.664.700.187 Proto-Oncogene Proteins c-mos 2
D12.776.624.664.700.188 Proto-Oncogene Proteins c-myb 30
D12.776.624.664.700.189 Proto-Oncogene Proteins c-myc 67
D12.776.624.664.700.191 Proto-Oncogene Proteins c-pim-1 1
D12.776.624.664.700.192 Proto-Oncogene Proteins c-rel 2
D12.776.624.664.700.194 Proto-Oncogene Proteins c-ret 42
D12.776.624.664.700.195 Proto-Oncogene Proteins c-sis 3
D12.776.624.664.700.198 Proto-Oncogene Proteins c-vav 4
D12.776.624.664.700.199 Proto-Oncogene Proteins c-yes 1
D12.776.624.664.700.200 Proto-Oncogene Proteins p21(ras) 73
D12.776.624.664.700.202 Proto-Oncogene Proteins pp60(c-src) 7
D12.776.624.664.700.204 raf Kinases 70
D12.776.624.664.700.642 Receptor, ErbB-2 595
D12.776.624.664.700.790 Receptor, ErbB-3 9
D12.776.624.664.700.791 Receptor, ErbB-4
D12.776.624.664.700.792 Receptor, Fibroblast Growth Factor, Type 3 28
D12.776.624.664.700.800 Receptor, Macrophage Colony-Stimulating Factor 1
D12.776.624.664.700.815 Receptor, Notch4
D12.776.624.664.700.830 Receptors, Thyroid Hormone 40
D12.776.624.664.700.913 RNA-Binding Protein EWS 15
D12.776.624.664.700.915 RNA-Binding Protein FUS 6
D12.776.624.664.700.936 RUNX1 Translocation Partner 1 Protein
D12.776.624.664.700.957 Stathmin 4
D12.776.624.664.700.960 T-Cell Acute Lymphocytic Leukemia Protein 1
D12.776.624.664.700.962 Wnt-5a Protein 5
D12.776.624.664.700.967 Wnt1 Protein 4
D12.776.624.664.700.978 Wnt2 Protein
D12.776.624.664.700.989 Zinc Finger Protein GLI1 7
D12.776.660 Nuclear Proteins 455
D12.776.660.049 Antennapedia Homeodomain Protein 1
D12.776.660.075 Ataxins 2
D12.776.660.100 BRCA1 Protein 103
D12.776.660.105 BRCA2 Protein 97
D12.776.660.167 CCAAT-Enhancer-Binding Proteins 11
D12.776.660.201 CDX2 Transcription Factor 3
D12.776.660.235 Chromosomal Proteins, Non-Histone 93
D12.776.660.264 Fanconi Anemia Complementation Group A Protein 1
D12.776.660.285 Fanconi Anemia Complementation Group D2 Protein 4
D12.776.660.289 Fanconi Anemia Complementation Group E Protein
D12.776.660.293 Fanconi Anemia Complementation Group F Protein
D12.776.660.323 Fanconi Anemia Complementation Group N Protein 4
D12.776.660.338 GADD45 Proteins
D12.776.660.352 Hepatocyte Nuclear Factors 5
D12.776.660.415 Homeobox Protein Nkx-2.2
D12.776.660.478 Host Cell Factor C1 2
D12.776.660.486 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.660.494 Inhibitor of Growth Protein 1
D12.776.660.502 Karyopherins 9
D12.776.660.526 Mad2 Proteins 1
D12.776.660.551 Mediator Complex 5
D12.776.660.600 NF-kappa B 220
D12.776.660.625 Antigens, Nuclear 11
D12.776.660.650 Nuclear Matrix-Associated Proteins 2
D12.776.660.675 Nuclear Receptor Coactivators 6
D12.776.660.688 Nuclear Receptor Interacting Protein 1 3
D12.776.660.691 Nucleolin
D12.776.660.694 Nucleophosmin 19
D12.776.660.700 Oncogene Protein p55(v-myc) 1
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.740 Proliferating Cell Nuclear Antigen 60
D12.776.660.745 Promyelocytic Leukemia Protein 4
D12.776.660.750 Protamines 43
D12.776.660.760 Proto-Oncogene Proteins c-fos 62
D12.776.660.763 Proto-Oncogene Proteins c-jun 18
D12.776.660.764 Proto-Oncogene Proteins c-mdm2 65
D12.776.660.765 Proto-Oncogene Proteins c-myc 67
D12.776.660.767 Proto-Oncogene Proteins c-rel 2
D12.776.660.768 ran GTP-Binding Protein 4
D12.776.660.769 Retinoblastoma Binding Proteins 3
D12.776.660.770 Retinoblastoma-Like Protein p107 4
D12.776.660.794 Retinoblastoma-Like Protein p130 5
D12.776.660.807 Retinoblastoma Protein 52
D12.776.660.820 Silent Information Regulator Proteins, Saccharomyces cerevisiae
D12.776.660.823 Thyroid Nuclear Factor 1
D12.776.660.912 Tumor Protein p73 6

MDM2 protein, Xenopus Chemical MeSH Browser

MDM2 protein, human Chemical MeSH Browser

Mdm2 protein, mouse Chemical MeSH Browser

Mdm2 protein, rat Chemical MeSH Browser

mdm2 protein, zebrafish Chemical MeSH Browser

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