Cytochrome P-450 CYP2C8 [cytochrom P450 CYP2C8]
- Terms
-
CYP2C8
CYPIIC8
cytochrom P-450 CYP2C8
-
CYP2C8
CYPIIC8
Cytochrome P450 MP-20
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8
S-Mephenytoin 4-Hydroxylase
A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE
- DUI
- D065727 MeSH Browser
- CUI
- M0590595
- Previous indexing
- Aryl Hydrocarbon Hydroxylases (2002-2014)
- History note
- 2015
- Public note
- 2015
Combination
- antagonists & inhibitors
- Cytochrome P-450 CYP2C8 Inhibitors
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- BI
- biosynthesis 2
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 3
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0