The aim of this research was to evaluate mutual interchangeability of four principally different biometric instrumental techniques designed for objective measurement of changes in the physical, mechanical, and topographical properties of the skin surface treated with commercial antiaging cosmetic products with hyaluronic acid. The following instrumental devices were used: Visioscope PC 35, Corneometer Multiprobe Adapter MPA 6, Reviscometer RVM 600, and 3D scanner Talysurf CLI 500. The comparison of the individual methods was performed using cluster analysis. The study involved 25 female volunteers aged 40-65. Measurements were taken before and after 30 daily in vivo applications of an antiaging preparation to the skin surface in the periorbital area. A slight reduction in skin surface roughness was recorded in 55% of the volunteers. On the contrary, a worsening from their initial states was detected in 25% of the subjects, while for 20%, no significant change was reported. Cluster analysis confirmed that the mentioned methodologies can be divided into two basic clusters, namely, a cluster of methods recording the changes in skin relief by means of optical techniques, and a cluster of methods investigating changes in hydration and anisotropy. In practice, the techniques in different clusters are not interchangeable and should be assessed separately.
- MeSH
- biometrie metody MeSH
- chemické jevy * MeSH
- dospělí MeSH
- kosmetické přípravky aplikace a dávkování MeSH
- kůže účinky léků MeSH
- kyselina hyaluronová aplikace a dávkování MeSH
- lidé středního věku MeSH
- lidé MeSH
- povrchové vlastnosti * MeSH
- viskosuplementy aplikace a dávkování MeSH
- zdraví dobrovolníci pro lékařské studie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
One of the complications of "diabetes mellitus" is termed diabetic foot syndrome, the first symptoms of which include changes in the skin's condition and properties. The skin becomes dehydrated, dry, and prone to excessive formation of the horny layer, its barrier function becoming weakened. This function can be restored by applying suitable cosmetic excipients containing active substances. The aim of this study was to evaluate and compare the effects of commercially available cosmetic products (CPs) designed for the care of diabetic foot, through a group of selected volunteers using noninvasive bioengineering methods. Statistical surveys (p < 0.05) evaluated these CPs as regards to their hydration effect and barrier properties. Special attention was devoted to CPs with the declared content of 10% urea, and that the influence of this preparation's ability to hydrate and maintain epidermal water in the epidermis was confirmed.
- MeSH
- aplikace kožní MeSH
- diabetická noha patologie MeSH
- dospělí MeSH
- epidermis účinky léků metabolismus patologie MeSH
- glycerol aplikace a dávkování chemie MeSH
- kosmetické přípravky aplikace a dávkování chemie MeSH
- kožní absorpce MeSH
- lidé středního věku MeSH
- lidé MeSH
- močovina aplikace a dávkování chemie MeSH
- permeabilita MeSH
- pomocné látky aplikace a dávkování chemie MeSH
- voda metabolismus MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
