OBJECTIVE: The prevalence of hyperostosis frontalis interna (HFI) was examined in different periods of the Carpathian Basin from 4900 BCE to 17th century AD. The study seeks to evaluate temporal changes in HFI and the possible impact of lifestyle on it. MATERIALS: The studied material consisted of 4668 crania from Hungary and Serbia. METHODS: The crania were analyzed employing macroscopic and endoscopic examination. RESULTS: In historic periods, sex and age played a pivotal role in HFI development. Among predominantly pastoralist populations of the 5th-8th and 10th centuries, prevalence of HFI was considerably higher than in the medieval populations of the 9th-17th centuries. CONCLUSIONS: In addition to age and sex, other factors could be implicated in HFI development. The physiological effects of the pastoralist lifestyle and diet on insulin regulation could explain the increased risk of developing HFI in the 5th-8th and 10th-century populations. SIGNIFICANCE: The study provides the first comprehensive dataset of HFI from different archaeological periods from the Carpathian Basin. It has implications for lifestyle and risk of HFI development in past populations. LIMITATIONS: The archaeological periods are not equally represented. SUGGESTIONS FOR FURTHER RESEARCH: In order to better understand the etiology of HFI, lifestyle factors can be used to elucidate the risk of developing HFI in ancient populations.
- MeSH
- archeologie dějiny metody MeSH
- čelní kost patologie MeSH
- dějiny 16. století MeSH
- dějiny 17. století MeSH
- hyperostosis frontalis interna dějiny MeSH
- lidé MeSH
- paleopatologie metody MeSH
- prevalence MeSH
- riziko MeSH
- životní styl * MeSH
- zkameněliny dějiny MeSH
- Check Tag
- dějiny 16. století MeSH
- dějiny 17. století MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- historické články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Maďarsko MeSH
- Srbsko MeSH
- MeSH
- časové faktory MeSH
- diabetes mellitus 1. typu * komplikace MeSH
- histologické techniky metody využití MeSH
- hyperostosis frontalis interna etiologie komplikace MeSH
- hyperostóza etiologie komplikace MeSH
- komplikace diabetu * diagnóza MeSH
- lidé MeSH
- metabolické nemoci prevence a kontrola MeSH
- osteoartróza * etiologie komplikace MeSH
- osteoporóza etiologie komplikace MeSH
- poruchy metabolismu glukózy komplikace MeSH
- radiografie metody využití MeSH
- remodelace kosti MeSH
- růstový hormon izolace a purifikace MeSH
- věkové faktory MeSH
- Check Tag
- lidé MeSH
