The paper studies clinical signs of hearing disorders caused by mutation in gene Cx26 in order to determine approaches to treatment and rehabilitation. The problem of primary prevention of such pathology as NSHL among children of Uzbek population is important thing in our region because of the high level of birth rate where we can see the marriages between two relatives who have blood relationship with each other (inbreeding). Factor of inbreeding comes out as additional precondition to investigate influence of the different genetic factors to NSHL in children. Determining mutation in gene Cx26 should lead to recommendation on testing this gene in all family members. In each specific case, during the obligatory medical and genetic consultation, we need to discuss on prevention of repeated cases in this family and in the following generations.
