As phospholipases of Salmonella species may play a role in the pathogenesis of gastrointestinal tract diseases. Salmonella newport, the causative agent of infantile diarrhoea was examined for the production of phospholipase. The enzyme was purified by gel filtration chromatography and was found to be a protein of molar mass ranging from 43 to 67 kDa. The purified enzyme alone or in combination with organisms, produced both structural and functional changes in rabbit ileum, contributing towards pathogenesis of diarrhoea due to this organism.
- MeSH
- fosfolipasy A izolace a purifikace farmakologie MeSH
- ileum účinky léků metabolismus patologie MeSH
- králíci MeSH
- průjem etiologie MeSH
- Salmonella enzymologie patogenita MeSH
- salmonelová infekce u zvířat etiologie MeSH
- tělesné tekutiny účinky léků metabolismus MeSH
- virulence MeSH
- vodní a elektrolytová rovnováha účinky léků MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH