Multiresidual analytical methods
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The multiresidue method using multisolvent extraction, SPE cleanup of the extract, HPLC with the use of OPA post-column reaction and fluorescence detection for the determination of N-methylcarbamate pesticides in food products was used. A matrix solid phase dispersion method of the isolation and extraction of carbamates was alternatively applied. In the introductory study 44 items of the food basket for the Czech Republic were analysed. In the major part of the studied samples, the considerable part of which was culinary treated, the concentration of the target carbamates was below the limit of the used detection method. In the concentration range of 10–100 μg/kg in the analysed samples of the studied analytes, aldicarb and its metabolites, e.g. methomyl and methiocarb were being found most frequently.
To follow the twelve "green analytical chemistry" (GAC) principles, it is necessary to continuously develop analytical extraction and determination methodologies to assess the presence of micropollutants, such as pharmaceuticals, in environmental samples. A reduction in the analysis time and solvent quantity, which is one of the GAC principles, has been achieved through a simplified solid-phase extraction (SPE) procedure combined with high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the determination of twenty-three pharmaceuticals in liquid environmental samples using N-vinylpyrrolidone-divinylbenzene copolymer (OASIS HLB) cartridges. The optimal SPE conditions were studied. In these optimized conditions, 82.6% of the data have a median recovery above 70% for all compounds in each sample. The relative standard deviations (RSDs) were below 14.4% and 22.0% for intra- and inter-day repeatability, respectively. Method detection limits (MDLs) and method quantification limits (MQLs) ranged from 0.011 to 188ngL(-1) and from 0.033 to 628ngL(-1), respectively. The applicability of the method was evaluated in real samples from natural and conventional wastewater treatment plants (WWTPs), and results were obtained in concentration ranges from 0.013 to 91.5μgL(-1) and from 0.004 to 49.1μgL(-1), respectively.
- MeSH
- chemické látky znečišťující vodu analýza izolace a purifikace MeSH
- chromatografie kapalinová MeSH
- extrakce na pevné fázi * MeSH
- léčivé přípravky analýza izolace a purifikace MeSH
- limita detekce MeSH
- monitorování životního prostředí metody MeSH
- odpadní voda chemie MeSH
- sladká voda chemie MeSH
- tandemová hmotnostní spektrometrie * MeSH
- Publikační typ
- časopisecké články MeSH
