• MeSH
• biologické modely MeSH
• dolní končetina patologie   MeSH
• klasifikace MeSH
• lidé MeSH
• nemoci cév klasifikace   MeSH
• příznaky a symptomy MeSH
• žilní trombóza diagnóza   patologie   MeSH
• Check Tag
• lidé MeSH

In this report the authors evaluate epidemiological evidence of thyroid cancer cases in a highly radiated territory in Poland--i.e. in the province of Opole after 1986. The analysis - based on logistic regression modelling of registered thyroid cancer and an ecological covariate (137Cs concentration)--shows differences in incidence in six distinguished radiation zones and two equal periods. The results of this study indicate a significant increase in incidence of thyroid cancer in 1995-2002 in males and in females comparing to the years 1987-1994. Moreover, a considerable rise of incidences has been noticed in the elevated isotope's concentration zones in females across the province in the analyzed periods. The data comprises all the thyroid cancer cases registered in Opole province in the years 1987-2002. The data originated from the Provincial Cancer Registry in Opole. The information on 137Cs concentrations was derived from the Polish Geological Institute in Warsaw. The computation was performed using WinBUGS software.

• MeSH
• černobylská havárie MeSH
• charakteristiky bydlení MeSH
• incidence MeSH
• lidé MeSH
• logistické modely MeSH
• nádory štítné žlázy epidemiologie   MeSH
• rizikové faktory MeSH
• rozložení podle pohlaví MeSH
• vztah dávky záření a odpovědi MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• multicentrická studie MeSH
• srovnávací studie MeSH
• Geografické názvy
• Polsko MeSH

In this geostatistical analysis we present the results of interrelation between unemployment rate and lung cancer incidence ratios in the Province of Opole, Poland. In the study, unemployment statistics and population data were analyzed together with the registered (histopathologically confirmed) lung cancer cases (C34, ICD10) in sex-stratified working age population (18-65 years). The data were collected in the years 2006-2008 in the Statistical Office in Opole and Opole Cancer Registry, Poland. The statistically significant positive correlation/interrelation between unemployment rate and lung cancer incidence ratios in male population was established; in females, this effect was statistically insignificant. The obtained results are consistent with the most up-to-date reports supporting the thesis that a higher burden of disease is observed in more deprived areas. The statistics may have practical relevance in terms of improving health status of the local population following economic reforms.

• MeSH
• dospělí MeSH
• incidence MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• nádory plic epidemiologie   MeSH
• nezaměstnanost statistika a číselné údaje   MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Polsko MeSH

In the study the results of the relation between infant (neonatal + post-neonatal) mortality and the gynaecological and unemployment factors are presented. The fi ndings are based on Bayesian modelling and indicate the possible infl uence of the unemployment situation on mortality, whereas no correlation was found as regards access to the availability of gynaecological health care. The main conclusion is that elevated unemployment which could be referred to a poor socioeconomic situation (amongst other factors) may force pregnant women to pay more attention to improving their life conditions, than to suffi cient medical controlling.

• MeSH
• gynekologie metody   statistika a číselné údaje   trendy   MeSH
• interpretace statistických dat MeSH
• kojenecká mortalita trendy   MeSH
• komplikace těhotenství epidemiologie   mortalita   prevence a kontrola   MeSH
• lékaři ekonomika   statistika a číselné údaje   MeSH
• lidé MeSH
• nezaměstnanost statistika a číselné údaje   trendy   MeSH
• sociální podmínky ekonomika   statistika a číselné údaje   trendy   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• srovnávací studie MeSH
• Geografické názvy
• Polsko MeSH

PURPOSE: Non-muscle-invasive bladder cancers (NMIBC) constitute 3-quarters of all primary diagnosed bladder tumors. For risk-adapted management of patients with NMIBC, different risk group systems and predictive models have been developed. This study aimed to externally validate EORTC2016, CUETO and novel EAU2021 risk scoring models in a multi-institutional retrospective cohort of patients with high-grade NMIBC who were treated with an adequate BCG immunotherapy. METHODS: The Kaplan-Meier estimates for recurrence-free survival and progression-free survival were performed, predictive abilities were assessed using the concordance index (C-index) and area under the curve (AUC). RESULTS: A total of 1690 patients were included and the median follow-up was 51 months. For the overall cohort, the estimates recurrence-free survival and progression-free survival rates at 5-years were 57.1% and 82.3%, respectively. The CUETO scoring model had poor discrimination for disease recurrence (C-index/AUC for G2 and G3 grade tumors: 0.570/0.493 and 0.559/0.492) and both CUETO (C-index/AUC for G2 and G3 grade tumors: 0.634/0.521 and 0.622/0.525) EAU2021 (c-index/AUC: 0.644/0.522) had poor discrimination for disease progression. CONCLUSION: Both the CUETO and EAU2021 scoring systems were able to successfully stratify risks in our population, but presented poor discriminative value in predicting clinical events. Due to the lack of data, model validation was not possible for EORTC2016. The CUETO and EAU2021 systems overestimated the risk, especially in highest-risk patients. The risk of progression according to EORTC2016 was slightly lower when compared with our population analysis.

• MeSH
• BCG vakcína terapeutické užití   MeSH
• hodnocení rizik MeSH
• invazivní růst nádoru MeSH
• karcinom z přechodných buněk * patologie   MeSH
• lidé MeSH
• lokální recidiva nádoru patologie   MeSH
• nádory močového měchýře * patologie   MeSH
• progrese nemoci MeSH
• retrospektivní studie MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH