OBJECTIVES: Most people gain weight on stopping smoking but the extent of weight gain varies greatly. Interventions aimed at all quitters to prevent weight gain on cessation have proven unpopular but targeting people who have gained excess weight immediately after quitting may improve uptake and cost-effectiveness. We examined whether early large postcessation weight gain predicts overall large weight gain. DESIGN: Retrospective cohort study. SETTING: Primary care setting-smoking cessation centre in Prague, Czech Republic. PARTICIPANTS: Out of 3537 patients treated between 2005 and 2013, 1050 were continuous abstainers (verified by carbon monoxide measurement) at 1-year follow-up and formed the cohort of the current report. 48.7% were women (n=511) with the mean age of 46 (±14.4) years. METHODS: In this retrospective cohort study, all patients underwent usual tobacco dependence treatment using evidence-based methods. Weight was measured prior to smoking cessation and at each visit after quitting. RESULTS: The mean weight gain in the first month (n=763) was 0.79% (±2.03%), in the second month (n=646) was 1.49% (±2.58%), for the third month (n=566) 2.33% (±3.44%) and 4.1% (±5.31%) after 1-year follow-up (n=1050). The regression coefficient per 1% rise in the first 3 months was +0.13% (95% CI -0.04% to 0.30%). A receiver operating curve analysis showed that patients gaining more than 0.98% of their baseline weight during first 3 months had a sensitivity of 66% and specificity of 44% for gaining 7% or more weight by 12 months. In addition, lower body mass index and an increase in appetite at 3 months after quitting were associated with greater weight gain, while using nicotine replacement therapy was associated with less weight gain at 1-year follow-up. CONCLUSIONS: People who stop smoking and gain a larger amount of weight early after quitting are not more likely to gain excessively at 1 year.

• MeSH
• chuť k jídlu účinky léků   MeSH
• dospělí MeSH
• hmotnostní přírůstek účinky léků   MeSH
• index tělesné hmotnosti MeSH
• kouření * epidemiologie   patofyziologie   terapie   MeSH
• látky pro odvykání kouření farmakologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nadváha * diagnóza   epidemiologie   etiologie   patofyziologie   MeSH
• nikotin farmakologie   MeSH
• odvykání kouření * psychologie   statistika a číselné údaje   MeSH
• prognóza MeSH
• retrospektivní studie MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Česká republika MeSH

• MeSH
• diabetes mellitus etiologie   patofyziologie   prevence a kontrola   MeSH
• dietoterapie metody   využití   MeSH
• genetická predispozice k nemoci genetika   prevence a kontrola   MeSH
• kardiovaskulární nemoci * prevence a kontrola   MeSH
• lidé MeSH
• metabolické nemoci etiologie   patofyziologie   prevence a kontrola   MeSH
• metabolický syndrom etiologie   patofyziologie   patologie   MeSH
• nadváha patofyziologie   prevence a kontrola   terapie   MeSH
• obezita * patofyziologie   prevence a kontrola   terapie   MeSH
• paradox obezity MeSH
• pohybová aktivita fyziologie   MeSH
• preventivní lékařství metody   MeSH
• rizikové faktory * MeSH
• statistika jako téma MeSH
• stravovací zvyklosti fyziologie   klasifikace   psychologie   MeSH
• tuková tkáň fyziologie   patofyziologie   patologie   MeSH
• zdravý životní styl fyziologie   klasifikace   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• přehledy MeSH

BACKGROUND: Low level of cardiorespiratory fitness has been recognized as an important independent and modifiable risk factor of increased morbidity and mortality. However, in standard outpatient settings, patients are not routinely screened for fitness and advantages of such testing for the management of type 2 diabetes have not been defined.AimTo describe the toleration of a fast, simple and practicable fitness test (2-min step-in-place test) by overweight/obese type 2 diabetics and their performance indicated by 2-min step-in-place test score (STS). To study short-term anthropometric, functional and metabolic changes following the implementation of the test in the selected population. METHODS: A total of 33 overweight/obese type 2 diabetics underwent, besides routine examination at the outpatient clinic, the fitness test (group A). Patients were asked to increase their regular physical activity with focus on walking without change in diet and chronic medication. Three to four months later, the subjects were tested again. An identical number of age- and sex-matched obese diabetics followed in our outpatient clinic (without fitness testing), was randomly selected from the Hospital Information System (control group B).FindingsAll patients subjected to fitness testing completed the protocol successfully. STS score was found to have a considerable range with differences between males and females at the borderline of statistical significance. The data are compliant with lower aerobic endurance of obese diabetics compared with healthy population. Within study period, the tested group presented with improvements in STS (referring especially to the males) as well as in several laboratory parameters of glucose and lipid homeostasis, glomerular function and subclinical inflammation with no reflection in anthropometry. Group B demonstrated no significant change. In conclusion, 2-min step-in-place test is fast, undemanding and well-tolerated by patients and personnel. Following its validation based on cardiopulmonary exercise testing, the test may prove recommendable for screening or self-monitoring purposes.

• MeSH
• diabetes mellitus 2. typu komplikace   patofyziologie   MeSH
• dospělí MeSH
• kardiorespirační zdatnost fyziologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nadváha komplikace   patofyziologie   MeSH
• obezita komplikace   patofyziologie   MeSH
• pilotní projekty MeSH
• rizikové faktory MeSH
• senioři MeSH
• zátěžový test metody   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH

Arterial stiffness is a marker of vascular damage. Although adiposity increases cardiovascular risk, the relationship between paediatric overweight and arterial stiffness is unclear. The study aimed to evaluate the simultaneous effect of hypertension and overweight on arterial stiffness using cardio-ankle vascular index (CAVI) and related novel, theoretically blood pressure (BP)-independent, index CAVI0. CAVI and CAVI0 were measured in 140 adolescent boys (16.0 ± 1.9 years) divided into age-matched groups: normal-weight normotensives, overweight normotensives, overweight white-coat hypertensives, and overweight essential hypertensives. Overweight normotensives had significantly lower CAVI and CAVI0 compared to normal-weight normotensives (4.81 ± 0.64 vs. 5.33 ± 0.66, p < .01; 7.10 ± 0.99 vs. 7.81 ± 1.00, p < .01, respectively). CAVI and CAVI0 in overweight essential hypertensives showed no significant difference compared to normal-weight normotensives and were significantly higher compared to overweight normotensives (5.32 ± 0.77 vs. 4.81 ± 0.64, p < .01; 7.77 ± 1.19 vs. 7.10 ± 0.99, p < .01, respectively). CAVI, but not CAVI0, was associated positively with diastolic pressure (0.022 mmHg-1, p = .002) and negatively with pulse pressure (-0.022 mmHg-1, p = .001), and it was significantly higher in overweight white-coat hypertensives compared to overweight normotensives (5.20 ± 0.63 vs. 4.81 ± 0.64, p < .05). The lowering effect of overweight on arterial stiffness indexed by CAVI and CAVI0 in hypertensive adolescents seems to counterbalance the early arteriosclerotic effect of essential hypertension. The increase in CAVI, but not CAVI0, in overweight white-coat hypertensives could be attributable to residual BP dependence of CAVI, which is not present in CAVI0. Under certain conditions, CAVI0 may offer a clinically relevant improved assessment of arterial stiffness superior to CAVI.

• MeSH
• analýza pulzové vlny MeSH
• arterioskleróza diagnóza   MeSH
• hypertenze diagnóza   MeSH
• kotník krevní zásobení   MeSH
• krevní tlak MeSH
• lidé MeSH
• mladiství MeSH
• nadváha patologie   patofyziologie   MeSH
• rizikové faktory MeSH
• tuhost cévní stěny MeSH
• zlepšení kvality MeSH
• Check Tag
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

BACKGROUND: Excessive body weight seems to be a risk factor for foot loading. We sought to investigate the effect of different body mass index (BMI) levels on plantar pressure distribution during walking. METHODS: In total, 163 women aged 45 to 65 years (mean ± SD: age, 57.4 ± 5.3 years; BMI, 27.0 ± 5.3) participated in the study. The women were divided, on the basis of BMI, into a normal-weight, overweight, or obese group. The study used the four following plantar pressure parameters (PPPs): contact percentage, absolute pressure impulse, relative pressure impulse, and absolute peak pressure, which were recorded in ten foot regions using a pressure measurement system. RESULTS: The normal-weight group, compared with the overweight and obese groups, had significantly lower absolute PPP values. In the hallux, second through fifth metatarsals, midfoot, and heel regions, we observed significant between-group differences in the two absolute PPPs (peak pressure and pressure impulse) (P < .001). Between-group differences in the relative PPPs were found in the fourth metatarsal, midfoot, and medial heel (relative impulse) and in the second metatarsal (contact percentage) (P < .001). CONCLUSIONS: Higher BMI values correspond to a higher load on the foot during walking in women. The relative foot load in obese women is characterized by a pressure increase in the lateral forefoot and midfoot and by a pressure decrease in the medial heel.

• MeSH
• biomechanika MeSH
• chůze (způsob) fyziologie   MeSH
• chůze fyziologie   MeSH
• index tělesné hmotnosti * MeSH
• lidé středního věku MeSH
• lidé MeSH
• nadváha patofyziologie   MeSH
• noha (od hlezna dolů) fyziologie   MeSH
• obezita patofyziologie   MeSH
• senioři MeSH
• tlak MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

• MeSH
• dospělí MeSH
• hydrokortison * krev   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mentální anorexie * krev   patofyziologie   MeSH
• mladiství MeSH
• mladý dospělý MeSH
• nadváha krev   patofyziologie   MeSH
• obezita * krev   patofyziologie   MeSH
• průřezové studie MeSH
• systém hypofýza - nadledviny * patofyziologie   MeSH
• systém hypotalamus-hypofýza * patofyziologie   MeSH
• tělesná hmotnost fyziologie   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• ženské pohlaví MeSH
• Publikační typ
• komentáře MeSH
• souhrny MeSH

AIM: To assess the relationship of children's physical activity and sedentary screen time with overweight and obesity in children living in different environments (town and city) in Lithuania. METHODS: An analysis of anthropometric data from 532 children living in town and city areas was performed. A youth physical activity questionnaire (YPAQ) was conducted to evaluate physical activity and sedentary screen time. RESULTS: The prevalence of overweight and obesity among the children was 25.5% in the town and 18.6% in the city. Children living in the town on average engaged 9.3 min/day less in moderate to vigorous physical activity (p=0.050) and had 33.2 MET-min/day lower energy expenditure than children living in the city. Sedentary screen time was extremely high on weekends in both town and city children. CONCLUSIONS: A higher prevalence of overweight and obesity and a lower amount of moderate-to-vigorous physical activity was found in children living in the town compared to children living in the city.

• MeSH
• antropometrie MeSH
• dítě MeSH
• energetický metabolismus MeSH
• lidé MeSH
• městské obyvatelstvo MeSH
• mladiství MeSH
• nadváha epidemiologie   patofyziologie   MeSH
• obezita dětí a dospívajících epidemiologie   patofyziologie   MeSH
• počítače využití   MeSH
• pohybová aktivita fyziologie   MeSH
• předměstské obyvatelstvo MeSH
• prevalence MeSH
• průřezové studie MeSH
• průzkumy a dotazníky MeSH
• sedavý životní styl * MeSH
• televize využití   MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• multicentrická studie MeSH
• Geografické názvy
• Litva MeSH

• Klíčová slova
• autonomní dysfunkce, baroreflexní citlivost, srdeční interval,
• MeSH
• autonomní nervový systém fyziologie   patofyziologie   MeSH
• baroreflex * fyziologie   MeSH
• diastola MeSH
• fotopletysmografie MeSH
• hypertenze etiologie   patofyziologie   MeSH
• index tělesné hmotnosti MeSH
• kohortové studie MeSH
• krevní tlak * fyziologie   MeSH
• lidé MeSH
• mladý dospělý MeSH
• nadváha * patofyziologie   MeSH
• pilotní projekty MeSH
• systola MeSH
• Check Tag
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• práce podpořená grantem MeSH

Dairy products have previously been reported to be associated with beneficial effects on body weight and metabolic risk markers. Moreover, primary data from the Diet, Obesity and Genes (DiOGenes) study indicate a weight-maintaining effect of a high-protein-low-glycaemic index diet. The objective of the present study was to examine putative associations between consumption of dairy proteins and changes in body weight and metabolic risk markers after weight loss in obese and overweight adults. Results were based on secondary analyses of data obtained from overweight and obese adults who completed the DiOGenes study. The study consisted of an 8-week weight-loss phase and a 6-month weight-maintenance (WM) phase, where the subjects were given five different diets varying in protein content and glycaemic index. In the present study, data obtained from all the subjects were pooled. Dairy protein intake was estimated from 3 d dietary records at two time points (week 4 and week 26) during the WM phase. Body weight and metabolic risk markers were determined at baseline (week -9 to -11) and before and at the end of the WM phase (week 0 and week 26). Overall, no significant associations were found between consumption of dairy proteins and changes in body weight and metabolic risk markers. However, dairy protein intake tended to be negatively associated with body weight gain (P=0·08; β=-0·17), but this was not persistent when controlled for total protein intake, which indicates that dairy protein adds no additional effect to the effect of total protein. Therefore, the present study does not report that dairy proteins are more favourable than other proteins for body weight regulation.

• MeSH
• biologické markery MeSH
• diabetes mellitus 1. typu epidemiologie   etiologie   prevence a kontrola   MeSH
• dietní proteiny aplikace a dávkování   škodlivé účinky   MeSH
• glykemický index MeSH
• hmotnostní úbytek MeSH
• index tělesné hmotnosti MeSH
• kardiovaskulární nemoci epidemiologie   etiologie   prevence a kontrola   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mléčné bílkoviny aplikace a dávkování   škodlivé účinky   MeSH
• nadváha dietoterapie   patofyziologie   prevence a kontrola   MeSH
• nízkoproteinová dieta MeSH
• obezita dietoterapie   patofyziologie   prevence a kontrola   MeSH
• podpora zdraví * MeSH
• recidiva MeSH
• redukční dieta MeSH
• riziko MeSH
• sekundární prevence MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• multicentrická studie MeSH
• práce podpořená grantem MeSH
• randomizované kontrolované studie MeSH
• srovnávací studie MeSH
• Geografické názvy
• Evropa MeSH

UNLABELLED: This study uncovered the patterns of moderate-to-vigorous physical activity (MVPA) in normal-weight and overweight/obese children before, during, and after school lessons. ActiTrainer-based MVPA was assessed over 2 school days (with and without a physical education lesson [PEL] in a sample of three hundred thirty-eight 9- to 11-year-old children (50.3 % female; 29.6 % overweight/obese), in the Czech Republic, during spring 2012. MVPA was quantified based on the step count (number), MVPA duration, and MVPA heart-rate response (minutes). No differences in the MVPA based on the time during the school day were confirmed in normal-weight versus overweight/obese girls, whereas normal-weight boys significantly exceed their overweight/obese peers in step count and after-school and daylong MVPA. Active participation in PEL contributes to a significantly higher step count, exercise duration, and MVPA heart-rate response in normal-weight and overweight/obese boys (p < 0.001) and normal-weight (p < 0.001) and overweight/obese (p < 0.04) girls during school time. Moreover, active participation in PEL significantly (p < 0.04) increases the overall daily step count, duration, and MVPA heart-rate response in normal-weight boys and overweight/obese girls. Active exercise during PEL accounted for 16.7 % of the total number of steps, 25.1 % of overall MVPA duration, and 24.1 % of the MVPA heart-rate response in 9- to 11-year-old children. During days with a PEL, a significantly (p < 0.02) higher number of overweight/obese girls and a higher number of normal-weight boys achieved the duration of 60 min/day of MVPA compared with days without a PEL. CONCLUSION: Adding one PEL or an equivalent amount of MVPA to the daily school routine appears to be a promising strategy to effectively increase daily MVPA, particularly among overweight/obese girls.

• MeSH
• cvičení fyziologie   MeSH
• dítě MeSH
• lidé MeSH
• nadváha patofyziologie   MeSH
• obezita patofyziologie   MeSH
• pohybová aktivita fyziologie   MeSH
• školy MeSH
• srdeční frekvence fyziologie   MeSH
• tělesná hmotnost MeSH
• tělesná výchova metody   MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Česká republika MeSH